Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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5-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48CYM50260
CAS:<p>CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R</p>Formula:C14H11Cl3FNO2Purezza:99.88%Colore e forma:SolidPeso molecolare:350.6GLP-1 receptor agonist 3
CAS:<p>GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.</p>Formula:C31H30FN5O4Purezza:98%Colore e forma:SolidPeso molecolare:555.6R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formula:C22H30ClNO3Colore e forma:SolidPeso molecolare:391.93AJ-76 hydrochloride
CAS:<p>AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.</p>Formula:C15H24ClNOColore e forma:SolidPeso molecolare:269.81SDZ-NVI-085
CAS:<p>SDZ-NVI-085 is an α1 adrenergic receptor agonist and a competitive antagonist of 5-hydroxytryptamine.</p>Formula:C15H21NO2SColore e forma:SolidPeso molecolare:279.4Dansyl-NECA
CAS:<p>Dansyl-NECA is a selective agonist of fluorescent adenosine A1 receptor.</p>Formula:C30H40N8O6SColore e forma:SolidPeso molecolare:640.7517-Phenyl trinor prostaglandin A2
CAS:<p>17-Phenyl trinor prostaglandin A2 is a synthetic analog of prostaglandin [1].</p>Formula:C23H28O4Colore e forma:SolidPeso molecolare:368.473Xanthine amine congener
CAS:<p>Xanthine amine congener is an Adenosine receptor antagonist.</p>Formula:C21H28N6O4Purezza:99.7%Colore e forma:SolidPeso molecolare:428.48URB447
CAS:<p>URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].</p>Formula:C25H21ClN2OColore e forma:SolidPeso molecolare:400.9Gestonorone Capronate
CAS:<p>Gestonorone Capronate is a progesterone used in benign prostatic hyperplasia and endometrial cancer studies.</p>Formula:C26H38O4Purezza:99.19%Colore e forma:SolidPeso molecolare:414.58BMS-639623
CAS:<p>BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.</p>Formula:C25H32FN7O2Colore e forma:SolidPeso molecolare:481.57GSK1842799
CAS:<p>GSK1842799 is a selective S1P1 receptor agonist with good oral bioavailability.</p>Formula:C24H30F9N3O6SColore e forma:SolidPeso molecolare:659.56Isopropyl dodec-11-enylfluorophosphonate
CAS:<p>Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits</p>Formula:C15H30FO2PPurezza:98%Colore e forma:SolidPeso molecolare:292.372-Thio-UTP tetrasodium
CAS:<p>2-Thio-UTP tetrasodium, a potent agonist for P2Y2, P2Y4, and P2Y6 receptors, serves as a crucial compound in cancer research [1].</p>Formula:C9H11N2Na4O14P3SColore e forma:SolidPeso molecolare:588.13Prostaglandin F2α serinol amide
CAS:<p>Prostaglandin F2α serinol amide, a serinolamide G protein-coupled receptor, elevates calcium levels in human non-small cell lung cancer cells. Additionally, Prostaglandin F2α functions as a luteinizing hormone in sheep and potentially serves as a nociceptive mediator in the spinal cord [1] [2] [3].</p>Formula:C23H41NO6Colore e forma:SolidPeso molecolare:427.582Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Formula:C17H12N6NaO3Purezza:98%Colore e forma:SolidPeso molecolare:371.312Foropafant
CAS:<p>Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).</p>Formula:C28H40N4SPurezza:99.67%Colore e forma:SolidPeso molecolare:464.712-O-Ethyl PAF C-16
CAS:<p>2-O-Ethyl PAF C-16, a homolog of Platelet-activating Factor (PAF) and competitive ligand for the Platelet-activating Factor Receptor (PAFR), inhibits the binding of PAF antagonist WEB 2086 to PAFR with an IC50 of 21 nM [1].</p>Formula:C26H56NO6PColore e forma:SolidPeso molecolare:509.709SKF 81297 hydrobromide
CAS:<p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.</p>Formula:C16H17BrClNO2Purezza:99.52%Colore e forma:SolidPeso molecolare:370.6711(Z),14(Z)-Eicosadienoic acid
CAS:<p>11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).</p>Formula:C20H36O2Purezza:99.94%Colore e forma:SolidPeso molecolare:308.5Carbidine dihydrochloride
CAS:<p>Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.</p>Formula:C13H20Cl2N2Purezza:98.59%Colore e forma:SolidPeso molecolare:275.217Robotnikinin
CAS:<p>Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.</p>Formula:C25H27ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:454.95N-5984
CAS:<p>N-5984, a β3-adrenergic receptor agonist, is used potentially for the treatment of obesity, overactive bladder and type 2 diabetes.</p>Formula:C20H22ClNO5Purezza:98%Colore e forma:SolidPeso molecolare:391.854-hydroxy Nebivolol hydrochloride
CAS:<p>4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.</p>Formula:C22H25F2NO5HClColore e forma:SolidPeso molecolare:457.915(S)-Fluprostenol
CAS:<p>15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.</p>Formula:C23H29F3O6Colore e forma:SolidPeso molecolare:458.5Prostaglandin E2 serinol amide
CAS:<p>Prostaglandin E2 Serinol Amide acts as a weak inhibitor against the hydrolysis of [3H]2-oleoylglycerol, but it is non-hydrolyzable and cannot produce PGE2. Consequently, it is unable to inhibit leukotriene B4 biosynthesis, superoxide production, migration, and the release of antimicrobial peptides [1].</p>Formula:C23H39NO6Colore e forma:SolidPeso molecolare:425.566MB-28767
CAS:<p>MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.</p>Formula:C22H30O5Colore e forma:SolidPeso molecolare:374.47SCH 206272
CAS:<p>SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.</p>Formula:C33H41Cl4N5O4Colore e forma:SolidPeso molecolare:713.52O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Formula:C23H36O3Colore e forma:SolidPeso molecolare:360.53MK-1421
CAS:<p>MK-1421 is a potent and selective sstr3 antagonist.</p>Formula:C27H24FN9O2Colore e forma:SolidPeso molecolare:525.54(-)-Isoproterenol hydrochloride
CAS:<p>(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.</p>Formula:C11H17NO3·CIHColore e forma:SolidPeso molecolare:247.72TGR5 agonist 3
CAS:<p>Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].</p>Formula:C28H48O5Colore e forma:SolidPeso molecolare:464.68MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Formula:C25H26Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:538.85Glucagon receptor antagonists-3
CAS:<p>Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.</p>Formula:C22H30FNO2Purezza:98%Colore e forma:SolidPeso molecolare:359.48KP496
CAS:<p>KP496 is a selective, dual antagonist for Thromboxane A2 receptor and Leukotriene D4 receptor.</p>Formula:C31H34ClN3O7S3Purezza:98%Colore e forma:SolidPeso molecolare:692.27Amtolmetin guacil
CAS:<p>Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。</p>Formula:C24H24N2O5Purezza:99.85%Colore e forma:White Needle-Shaped CrystalPeso molecolare:420.46BI-167107
CAS:<p>BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).</p>Formula:C21H26N2O4Colore e forma:SolidPeso molecolare:370.44Sulmazole
CAS:<p>Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.</p>Formula:C14H13N3O2SPurezza:99.94%Colore e forma:SolidPeso molecolare:287.34CV1808
CAS:<p>CV-1808 is a coronary vasodilator, antihypertensive, and antipsychotic following systemic administration in vivo. CV-1808 is an adenosine A2 receptor agonist.</p>Formula:C16H18N6O4Colore e forma:Off-White To Pale Yellow SolidPeso molecolare:358.35Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Formula:C18H23FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:318.39JTE-952
CAS:<p>JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.</p>Formula:C30H34N2O6Purezza:98%Colore e forma:SolidPeso molecolare:518.6RP-001
CAS:<p>RP-001 is a selective agonist of picomolar short-acting S1P1 (EDG1)(EC50 of 9 pM), has little activity on S1P2-S1P4 and only moderate affinity for S1P5.</p>Formula:C24H24N4O4Purezza:98%Colore e forma:SolidPeso molecolare:432.4715(R)-Prostaglandin D2
CAS:<p>15(R)-Prostaglandin D2 functions as a DP(2) receptor (Prostaglandin Receptor) agonist with potential roles in prostatic hormone signaling and exhibits anti-inflammatory properties. It enhances actin polymerization in human eosinophils and elevates cAMP levels in platelets [1].</p>Formula:C20H32O5Colore e forma:SolidPeso molecolare:352.471PSB-1114 tetrasodium
CAS:<p>PSB-1114 tetrasodium, a stable P2Y2 agonist (EC50: 134 nM), is >50x more selective over P2Y4 and P2Y6.</p>Formula:C10H15F2N2Na4O13P3SPurezza:98%Colore e forma:SolidPeso molecolare:626.17AGN 192836
CAS:<p>AGN 192836 is a potent and selective α2 adrenergic agonist (EC50s: 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor).</p>Formula:C12H13N3O2Colore e forma:SolidPeso molecolare:231.25BAY-784
CAS:<p>BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R).</p>Formula:C29H26ClF4N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:672.11MRS2693 trisodium
CAS:<p>MRS2693 trisodium, a selective P2Y6 agonist with an EC50 of 0.015 μM, demonstrates cytoprotective effects in a mouse hindlimb skeletal muscle ischemia-reperfusion injury model by reducing NF-kappaB activation and stimulating the ERK1/2 pathway [1] [2].</p>Formula:C9H10IN2Na3O12P2Colore e forma:SolidPeso molecolare:596Hh-Ag1.5
CAS:<p>Hh-Ag1.5 is a dual Hedgehog/Smo agonist (EC50/Ki: 0.5-2.3 nM), reprograms hepatic stem cells, and differentiates hiPSCs into neural/skin cells.</p>Formula:C28H26ClF2N3OSPurezza:99.8%Colore e forma:SolidPeso molecolare:526.04LX-1031
CAS:<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Formula:C28H25F3N4O4Purezza:97.123% - 98.97%Colore e forma:SolidPeso molecolare:538.52trans-J-113863
CAS:<p>Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].</p>Formula:C30H37Cl2IN2O2Colore e forma:SolidPeso molecolare:655.44BAY-298
CAS:<p>BAY-298: oral LH-R antagonist; IC50: 96nM (hLH), 23nM (rLH), 78nM (cLH); first to lower sex hormones in vivo.</p>Formula:C27H21ClFN3O2Purezza:98%Colore e forma:SolidPeso molecolare:473.93β3-AR agonist 2
CAS:<p>β3-AR agonist 2 is a potent and selective agonist of β3-adrenergic receptor (β3-AR with an EC50 of 8 nM).</p>Formula:C27H38N4O7SPurezza:98%Colore e forma:SolidPeso molecolare:562.68CCR2 antagonist 4
CAS:<p>CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM</p>Formula:C21H21ClF3N3O2Purezza:99.86%Colore e forma:SolidPeso molecolare:439.86RXFP1 receptor agonist-5
CAS:<p>RXFP1 receptor agonist-5 (Example 98) is an agonist that targets the RXFP1 receptor and demonstrates its bioactivity by inhibiting cAMP production in HEK293</p>Formula:C30H23F6N3O7Colore e forma:SolidPeso molecolare:651.51CAY10508
CAS:<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Formula:C21H14Br2N2O2Colore e forma:SolidPeso molecolare:486.2L-644,698
CAS:<p>L-644,698 is a selective agonist of human prostanoid DP receptor.</p>Formula:C21H31NO4SPurezza:98%Colore e forma:SolidPeso molecolare:393.54SB-649701
CAS:<p>SB-649701 is a potent antagonist of the human CCR8 receptor, exhibiting a pIC50 value of 7.7, and is utilized in asthma research [1].</p>Formula:C27H28N4O3Purezza:98%Colore e forma:SolidPeso molecolare:456.54IPG7236
CAS:<p>IPG7236, a selective CCR8 antagonist, demonstrates notable tumor suppression in a mouse xenograft model of human breast cancer and is applicable in cancer</p>Formula:C23H31N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:429.58NNC 26-9100
CAS:<p>Somatostatin sst4 receptor agonist</p>Formula:C22H25BrCl2N6SPurezza:98%Colore e forma:SolidPeso molecolare:556.35Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Formula:C16H24ClNO2Colore e forma:SolidPeso molecolare:297.82CMPD167
CAS:<p>CMPD167 (MRK-1) is a potent, orally active inhibitor of CCR5 with significant in vitro antiviral efficacy [1].</p>Formula:C35H47FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:574.77Cenerimod
CAS:<p>Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma.</p>Formula:C25H31N3O5Purezza:97.43% - 99.97%Colore e forma:SolidPeso molecolare:453.53LMD-009
CAS:<p>LMD-009 is a non-peptide, selective CCR8 agonist that mediates chemotaxis, inositol phosphate accumulation, and calcium release, with an EC50 of 11–87 nM.</p>Formula:C29H33N3O3Purezza:98%Colore e forma:SolidPeso molecolare:471.59PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Formula:C24H31N3O3Purezza:98%Colore e forma:SolidPeso molecolare:409.52EP4 receptor agonist 2
CAS:<p>EP4 receptor agonist 2 (compound 31) is a potent EP4 receptor agonist, demonstrating an EC50 value of 0.8 nM and K_i values of >100,000, 38,000, and 3.1 nM for the EP2, EP3, and EP4 receptors, respectively [1].</p>Formula:C27H32ClNO4Colore e forma:SolidPeso molecolare:470.01Fiboflapon
CAS:<p>Fiboflapon (GSK2190915), an oral 5-lipoxygenase inhibitor, binds FLAP at 2.9 nM, inhibits LTB4 with 76 nM IC50.</p>Formula:C38H43N3O4SPurezza:97.01%Colore e forma:SolidPeso molecolare:637.83O-2050
CAS:<p>O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.</p>Formula:C23H31NO4SPurezza:98%Colore e forma:SolidPeso molecolare:417.56Abediterol
CAS:<p>Abediterol (LAS100977): potent, long-acting beta-2 agonist for asthma and COPD treatment.</p>Formula:C25H30F2N2O4Colore e forma:SolidPeso molecolare:460.51L 163255
CAS:<p>L 163255 is a type of growth hormone secretagogue (GHS).</p>Formula:C28H38N4O4SColore e forma:SolidPeso molecolare:526.69PF-184563
CAS:<p>PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.</p>Formula:C21H23ClN6Purezza:99.67%Colore e forma:SolidPeso molecolare:394.9Prostaglandin E1 ethanolamide
CAS:<p>Prostaglandin E1 ethanolamide, an analog of Prostaglandin E1 (PGE1), can potentially inhibit the GLI2-induced expression of target genes such as Gli1 and Ptch1, thereby reducing tumor growth [1].</p>Formula:C22H39NO5Colore e forma:SolidPeso molecolare:397.55Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Formula:C16H21N3O2C4H4O4Colore e forma:SolidPeso molecolare:345.4E1R
CAS:<p>E1R is a positive sigma-1 receptor (Sig1R PAM) allosteric modulator. It has a cognition-enhancing activity.</p>Formula:C13H16N2O2Colore e forma:SolidPeso molecolare:232.2811-deoxy-16,16-dimethyl Prostaglandin E2
CAS:<p>11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro.</p>Formula:C22H36O4Colore e forma:SolidPeso molecolare:364.526MSX-2
CAS:<p>MSX-2 is an A2A adenosine receptor antagonist.</p>Formula:C21H22N4O4Purezza:98%Colore e forma:SolidPeso molecolare:394.42GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Formula:C29H32ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:534.05RBC10
CAS:<p>RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-</p>Formula:C24H25ClN2O2Purezza:99.71%Colore e forma:SolidPeso molecolare:408.92CRTH2-IN-1
CAS:<p>CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.</p>Formula:C21H21FN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:416.47Sonepiprazole
CAS:<p>Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation</p>Formula:C21H27N3O3SPurezza:99.81%Colore e forma:SolidPeso molecolare:401.52ATL802
CAS:<p>ATL802 is an adenosine A2B Receptor antagonist.</p>Formula:C24H22F3N7O3Purezza:98%Colore e forma:SolidPeso molecolare:513.47BLT2 probe 1
CAS:<p>BLT2 Probe 1, based on CAY10583, is a fluorescent tool for studying BLT2 pharmacology, aiding research in diabetes and GI lesion treatment.</p>Formula:C50H45N3O11SPurezza:98%Colore e forma:SolidPeso molecolare:895.97Prostaglandin D3
CAS:<p>Prostaglandin D3 (PGD3) functions as an inhibitor of platelet aggregation and modulates autonomic neurotransmission in humans [1].</p>Formula:C20H30O5Purezza:98%Colore e forma:SolidPeso molecolare:350.45LTB4 antagonist 3
CAS:<p>Compound 24e, a leukotriene B4 (LTB4) antagonist, exhibits an inhibitory concentration 50 (IC50) of 477 nM and demonstrates anti-inflammatory activity [1].</p>Formula:C29H27NO6Purezza:98%Colore e forma:SolidPeso molecolare:485.53AM841
CAS:<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Formula:C26H39NO3SPurezza:98%Colore e forma:SolidPeso molecolare:445.66Bivamelagon hydrochloride
CAS:<p>MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction.</p>Formula:C35H54Cl2N4O4Purezza:100%Colore e forma:SolidPeso molecolare:665.73TASP 0277308
CAS:<p>NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activating protein (fap) inhibitor.</p>Formula:C23H28Cl2N6O3SColore e forma:SolidPeso molecolare:539.48Firazorexton hydrate
CAS:<p>Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM.</p>Formula:C22H25F3N2O4SH2OColore e forma:SolidPeso molecolare:497.53BLT2 antagonist-1
CAS:<p>BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not</p>Formula:C26H26FNO4Purezza:98%Colore e forma:SolidPeso molecolare:435.49A1/A3 AR antagonist 3
CAS:<p>A1/A3 AR Antagonist 3 is a dual A1R/A3R antagonist that demonstrates high affinity within the low-micromolar to nanomolar range, and is potentially useful in</p>Formula:C22H19N5O3Purezza:98%Colore e forma:SolidPeso molecolare:401.42NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Formula:C18H24ClFN2O2Purezza:98%Colore e forma:SolidPeso molecolare:354.85RP-23618
CAS:<p>RP-23618 is a non-peptidic antagonist of RANTES.</p>Formula:C30H35N5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:577.76Sigma-1 receptor antagonist 1
CAS:<p>Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.</p>Formula:C19H23Cl2N3OPurezza:99.92%Colore e forma:SolidPeso molecolare:380.31TG6-129
CAS:<p>TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM IC50.</p>Formula:C20H18FN5O3S3Purezza:99.55%Colore e forma:SolidPeso molecolare:491.58Todralazine hydrochloride
CAS:<p>Todralazine hydrochloride, a β2AR blocker with antioxidant properties, is used in hypertension studies.</p>Formula:C11H13ClN4O2Purezza:99.91%Colore e forma:SolidPeso molecolare:268.7Dersalazine sodium
CAS:<p>Dersalazine, potential ulcerative colitis drug, inhibits PAF & TNFα, reduces inflammation and MPO activity in rats.</p>Formula:C35H32N6NaO4Purezza:98%Colore e forma:SolidPeso molecolare:623.669CP-96486
CAS:<p>CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).</p>Formula:C31H23ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:502.9916-phenoxy tetranor Prostaglandin E2
CAS:<p>16-phenoxy tetranor PGE2, the free acid form of sulprostone, results from the hydrolysis of the methylsulfonamide bond. It is identified as a minor metabolite in human plasma following the parenteral administration of sulprostone.</p>Formula:C22H28O6Colore e forma:SolidPeso molecolare:388.46AZD9898
CAS:<p>AZD9898 inhibits leukotriene-C4 synthetase (IC50: 0.28 nM), aids asthma research, and reduces GABA binding, liver toxicity.</p>Formula:C20H19ClF3N3O4Purezza:99.26%Colore e forma:SolidPeso molecolare:457.83Tafluprost ethyl ester
CAS:<p>Tafluprost, an analog of prostaglandin F2α (PGF2α) that primarily targets the FP receptor, is employed in glaucoma treatment. Tafluprost (free acid) serves as a potent FP receptor agonist with a Ki value of 0.4 nM. Its derivative, tafluprost ethyl ester, potentially offers enhanced lipid solubility relative to its free acid form, possibly leading to superior tissue absorption and reduced effective concentration requirements.</p>Formula:C24H32F2O5Colore e forma:SolidPeso molecolare:438.512VCH-286
CAS:<p>VCH-286 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist.</p>Formula:C34H50F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:600.78UWA-101 hydrochloride
CAS:<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Formula:C13H18ClNO2Colore e forma:SolidPeso molecolare:255.74Facinicline hydrochloride
CAS:<p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>Formula:C15H19ClN4OPurezza:98.70%Colore e forma:SolidPeso molecolare:306.79L 743310
CAS:<p>L 743310 is an antagonist of the neurokinin-1 receptor.</p>Formula:C30H33BrF6N4O2Purezza:98%Colore e forma:SolidPeso molecolare:675.5Obestatin(rat) TFA
CAS:<p>Obestatin(rat) TFA, a 23-amino-acid peptide, modulates appetite, gut motility, and body weight; binds GPR39; has anti-inflammatory and antioxidant effects.</p>Formula:C116H175F3N34O33Colore e forma:SolidPeso molecolare:2630.83RS100329 hydrochloride
CAS:<p>RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.</p>Formula:C20H26ClF3N4O3Purezza:99.95%Colore e forma:SolidPeso molecolare:462.89LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Formula:C28H38N2O2Colore e forma:SolidPeso molecolare:434.61NBI 35965 methanesulfonate
CAS:NBI 35965 hydrochloride is a CRF1 antagonist.Formula:C22H26Cl2N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:497.44A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Formula:C28H35F3N2O5Colore e forma:SolidPeso molecolare:536.59Vatinoxan hydrochloride
CAS:<p>Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.</p>Formula:C20H27ClN4O4SPurezza:98%Colore e forma:SolidPeso molecolare:454.97BMS-194449
CAS:<p>BMS-194449 is a full beta 3 agonist.</p>Formula:C24H24F4N2O6SColore e forma:SolidPeso molecolare:544.52CP-96021 hydrochloride
CAS:CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).Formula:C29H22ClFN4OSPurezza:98%Colore e forma:SolidPeso molecolare:529.03EP2 receptor agonist 4
CAS:<p>EP2 receptor agonist 4 selectively activates the EP2 receptor with an efficacy concentration (EC50) of 43 nM [1].</p>Formula:C23H36O5Colore e forma:SolidPeso molecolare:392.53Leukotriene B4-3-aminopropylamide
CAS:<p>Leukotriene B4 (LTB4)-3-aminopropylamide is an analog of LTB4 that exhibits potent and selective binding to the BLT1 receptor with Ki values of 5.1 nM at BLT1 and 1,227 nM at BLT2, indicating its high affinity for BLT1 over BLT2. This compound's effects are mediated through interactions with two receptors, BLT1 and BLT2.</p>Formula:C23H40N2O3Colore e forma:SolidPeso molecolare:392.6SRX246
CAS:<p>SRX246: potent CNS-penetrant V1a antagonist (Ki=0.3 nM), inactive at V1b/V2, negligible binding at 64 other receptor classes.</p>Formula:C42H49N5O5Purezza:98%Colore e forma:SolidPeso molecolare:703.87GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Formula:C19H29FN4O8S2Purezza:98%Colore e forma:SolidPeso molecolare:524.58MNI-444
CAS:<p>MNI-444 is a PET radiotracer for adenosine 2A receptors.</p>Formula:C24H26FN9O2Colore e forma:SolidPeso molecolare:491.52Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Formula:C21H28N2O3Purezza:98%Colore e forma:SolidPeso molecolare:356.46Befiradol
CAS:<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Formula:C20H22ClF2N3OColore e forma:SolidPeso molecolare:393.86β3-AR agonist 1
CAS:<p>β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/</p>Formula:C22H28N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:444.55(Rac)-Modipafant
CAS:<p>(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.</p>Formula:C34H29ClN6O3Purezza:97.96% - 98.09%Colore e forma:SolidPeso molecolare:605.09GW405833 hydrochloride
CAS:<p>GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].</p>Formula:C23H25Cl3N2O3Colore e forma:SolidPeso molecolare:483.825-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Formula:C16H21ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:352.82MK-0493
CAS:<p>MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.</p>Formula:C30H38ClF2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:546.09Kisspeptin 234 TFA
CAS:<p>Kisspeptin 234 TFA is a 10-amino acid peptide analog of Kisspeptin 10 [1] that functions as an antagonist to the kisspeptin receptor (KISS1, GPR54).</p>Formula:C63H78N18O13·xC2HF3O2Colore e forma:SolidPeso molecolare:1409.43Fazamorexant
CAS:<p>Fazamorexant (YZJ-1139) is a powerful orexin receptor antagonist effective for insomnia research.</p>Formula:C25H25FN4O2Colore e forma:SolidPeso molecolare:432.49ATP-γ-S tetrasodium
CAS:<p>Collagen, Type I, from bovine achilles tendon is a type I collagen extracted from bovine achilles tendon.</p>Formula:C10H12N5Na4O12P3SColore e forma:SolidPeso molecolare:611.172-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Formula:C11H14N2OPurezza:97.18%Colore e forma:SolidPeso molecolare:190.242-Linoleoyl Glycerol
CAS:<p>2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.</p>Formula:C21H38O4Colore e forma:SolidPeso molecolare:354.531RXFP1 receptor agonist-1
CAS:<p>RXFP1 receptor agonist-1 (Example 2), an agonist of the RXFP1 receptor, suppresses cAMP production in HEK293 cells that constitutively express the human RXFP1,</p>Formula:C31H29F7N2O4Colore e forma:SolidPeso molecolare:626.56NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Formula:C21H34N2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:538.63(Rac)-PF-4136309(1341224-83-6 Free base)
CAS:<p>PF-4136309 (INCB8761, PF-04136309) is a highly effective and selective oral CCR2 antagonist with good bioavailability, with an IC50 value of 5.2 nM for human</p>Formula:C29H31F3N6O3Colore e forma:SolidPeso molecolare:568.59CY 208-243
CAS:<p>CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.</p>Formula:C19H18N2Purezza:98%Colore e forma:SolidPeso molecolare:274.36Ro-24-0238
CAS:<p>Ro-24-0238 blocks PAF, curbing thromboxane creation and inflammation caused by PAF release.</p>Formula:C27H36N2O2Purezza:98%Colore e forma:SolidPeso molecolare:420.59Bima SA
CAS:<p>Bimatoprost Serinol Amide (Bima SA), a prostaglandin analog, shows research potential for glaucoma [1].</p>Formula:C26H39NO6Colore e forma:SolidPeso molecolare:461.59Hemopressin(rat) TFA
CAS:<p>Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.</p>Formula:C55H78F3N13O14Colore e forma:SolidPeso molecolare:1202.28L-796568 dihydrochloride
CAS:<p>L-796568: potent β3 agonist (EC50 = 3.6 nM), >600-fold selectivity vs β1/β2, good oral bioavailability, long action.</p>Formula:C31H29Cl2F3N4O3S2Colore e forma:SolidPeso molecolare:697.62Alclofenac
CAS:<p>Alclofenac (W-7320) aids chronic rheumatism by affecting acute phase proteins and L-tryptophan binding.</p>Formula:C11H11ClO3Purezza:99.89%Colore e forma:SolidPeso molecolare:226.66Prostaglandin D2-1-glyceryl ester
CAS:<p>Prostaglandin D2-1-glyceryl ester (PGD2-G; PGD2 2-glyceryl ester) is a chemical compound known for its significance in various biological processes. This compound, commonly referred to by its abbreviations PGD2-G or PGD2 2-glyceryl ester, plays a crucial role in the mediation of physiological functions.</p>Formula:C23H38O7Colore e forma:SolidPeso molecolare:426.55NBI-34041
CAS:<p>NBI-34041: High-affinity CRF1 antagonist; reduces endocrine responses to CRF challenges.</p>Formula:C22H26Cl2N4Colore e forma:SolidPeso molecolare:417.37Ebopiprant
CAS:<p>Ebopiprant (OBE022) is a prostaglandin F2α (PGF2α) receptor antagonist that can be used to study obesity.</p>Formula:C30H34FN3O5S2Purezza:98.73%Colore e forma:SolidPeso molecolare:599.74UNC9994 hydrochloride
CAS:<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Formula:C21H23Cl3N2OSColore e forma:SolidPeso molecolare:457.848-iso-15(R)-Prostaglandin F2α
CAS:<p>8-iso-15(R)-Prostaglandin F2α (8-iso-15(R) PGF2α) is a chemically distinct member within a broad group of prostaglandin-like eicosanoids, produced through the free radical peroxidation of arachidonic acid contained in membrane phospholipids. It represents the C-15 epimer of 8-isoPGF2α, distinguished as the sole isoprostane isomer extensively examined across numerous biological systems.</p>Formula:C20H34O5Colore e forma:SolidPeso molecolare:354.5CR-6086
CAS:<p>CR6086: potent EP4 antagonist with DMARD effects, low Ki (16.6 nM), and specific anti-inflammatory action.</p>Formula:C26H27F3N2O3Colore e forma:SolidPeso molecolare:472.5GLP-1R agonist 17
CAS:<p>GLP-1R agonist 17 excels in stimulating GLP-1 receptors, useful for cardiovascular metabolic disease research.</p>Formula:C28H26ClFN4O4SColore e forma:SolidPeso molecolare:569.05Nemonapride
CAS:<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formula:C21H26ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.9MRS5698
CAS:<p>MRS5698, an A3 adenosine receptor agonist with Ki ~3 nM, blocks chronic pain, highly selective (>1000-fold over A1/A2A).</p>Formula:C28H23ClF2N6O3Purezza:98%Colore e forma:SolidPeso molecolare:564.97ST4206
CAS:<p>ST4206 is an antagonist of adenosine A2A. For adenosine A2A receptor and adenosine A1 receptor, the Kis values are 12 nM and 197 nM , respectively.</p>Formula:C12H14N8OPurezza:98%Colore e forma:SolidPeso molecolare:286.29(R)-JNJ-31020028
CAS:<p>(R)-JNJ-31020028: High-affinity, selective brain-penetrant Y2 receptor antagonist; pIC50: human 8.07, rat 8.22, mouse 8.21.</p>Formula:C34H36FN5O2Purezza:98%Colore e forma:SolidPeso molecolare:565.68AGN 210676
CAS:<p>AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).</p>Formula:C23H29NO5SPurezza:98%Colore e forma:SolidPeso molecolare:431.55Tradipitant
CAS:<p>Tradipitant (VLY-686) is an antagonist of neurokinin-1.</p>Formula:C28H16ClF6N5OPurezza:99.42%Colore e forma:SolidPeso molecolare:587.9(1S)-CCR2 antagonist 1
CAS:<p>(1S)-CCR2 antagonist 1, a left-handed chiral form of CCR2 antagonist 1, exhibits high affinity and a long residence time as a CCR2 antagonist, with an inhibition constant (K i) of 2.4 nM [1].</p>Formula:C28H32BrF3N2OColore e forma:SolidPeso molecolare:549.47Cipralisant
CAS:<p>Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.</p>Formula:C14H20N2Purezza:98%Colore e forma:SolidPeso molecolare:216.32Prostaglandin E2 Ethanolamide
CAS:<p>Prostaglandin E2 Ethanolamide (PGE 2 -EA), an analog of PGE2, is enzymatically synthesized through COX-2 oxygenation of endocannabinoids. It has the potential to modulate the production of the proinflammatory cytokine TNF-α in human blood and monocytic cells [1] [2].</p>Formula:C22H37NO5Colore e forma:SolidPeso molecolare:395.54Tianagliflozin
CAS:<p>Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C21H25ClO5Purezza:98%Colore e forma:SolidPeso molecolare:392.87MF266-1
CAS:<p>MF266-1, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of osteoarthritis and rheumatoid.</p>Formula:C24H17ClF3NO3SColore e forma:SolidPeso molecolare:491.91CB-25
CAS:<p>CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells</p>Formula:C25H41NO3Purezza:98%Colore e forma:SolidPeso molecolare:403.6S1R agonist 1 hydrochloride
CAS:<p>S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values of 0.93 nM for S1R and 72 nM for S2R, and has demonstrated</p>Formula:C20H26ClNOPurezza:98%Colore e forma:SolidPeso molecolare:331.88LPA1 receptor antagonist 1
CAS:<p>LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the study of idiopathic pulmonary fibrosis.</p>Formula:C28H26N4O4Purezza:99.46% - 99.56%Colore e forma:SolidPeso molecolare:482.53BMS-960
CAS:<p>BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.</p>Formula:C26H23F3N4O5Purezza:97.66% - 98.69%Colore e forma:SolidPeso molecolare:528.48RP-001 hydrochloride
CAS:<p>RP-001 hydrochloride: S1P1 agonist, EC50 9 pM; low activity on S1P2-4, moderate S1P5 affinity.</p>Formula:C24H25ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:468.93MF498
CAS:<p>MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed a strong binding affinity for the EP4 receptor (Ki: 0.7 nM).</p>Formula:C32H33N3O7SPurezza:98%Colore e forma:SolidPeso molecolare:603.69SQ 26655
CAS:<p>SQ 26655 is an antagonist of thromboxane A2/prostaglandin H2.</p>Formula:C21H34O4Purezza:98%Colore e forma:SolidPeso molecolare:350.49RXFP1 receptor agonist-2
CAS:<p>RXFP1 Receptor Agonist-2 (Example 124), an EC50 value of 1 nM [1].</p>Formula:C33H32F7N3O5Colore e forma:SolidPeso molecolare:683.61Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Formula:C15H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:247.33Setipafant
CAS:<p>Setipafant is an antagonist of the platelet-activating factor.</p>Formula:C26H23ClN6O2SPurezza:98%Colore e forma:SolidPeso molecolare:519.02Ritodrine
CAS:<p>Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].</p>Formula:C17H21NO3Colore e forma:SolidPeso molecolare:287.35Mesembrine
CAS:<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Formula:C17H23NO3Colore e forma:SolidPeso molecolare:289.37L-749329
CAS:<p>L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.</p>Formula:C28H29NO8SPurezza:98%Colore e forma:SolidPeso molecolare:539.6GSK726701A
CAS:<p>GSK726701A is a new type of prostaglandin E2 receptor 4 (EP4) partial agonist (pEC50: 7.4).</p>Formula:C24H22FNO5Purezza:98%Colore e forma:SolidPeso molecolare:423.43GYKI-46903 HCl
CAS:<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Formula:C17H21ClFNO2Colore e forma:SolidPeso molecolare:325.81S1PR1-MO-1
CAS:<p>S1PR-MO-1 is a modulator of sphingosine-1-phosphate receptor and is used to study hyperproliferative inflammatory diseases.</p>Formula:C25H29N3O3Purezza:98%Colore e forma:SolidPeso molecolare:419.52L 640035
CAS:<p>L 640035 inhibits human platelet aggregation which is induced by arachidonic acid, collagen, and the prostaglandin-endoperoxide analog of U44069.</p>Formula:C15H12O3SPurezza:98%Colore e forma:SolidPeso molecolare:272.32Emicerfont
CAS:<p>Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).</p>Formula:C22H24N6O2Purezza:98%Colore e forma:SolidPeso molecolare:404.46Binedaline
CAS:<p>Binedaline is a selective norepinephrine reuptake inhibitor with Ki value of 25 nM.</p>Formula:C19H23N3Purezza:98%Colore e forma:SolidPeso molecolare:293.41CJ-42794
CAS:<p>CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).</p>Formula:C22H17ClFNO4Purezza:99.92%Colore e forma:SolidPeso molecolare:413.83CP 122721 hydrochloride
CAS:<p>CP 122721 hydrochloride is a potent and selective non-peptide (nonpeptide) neurokinin NK1 antagonist, demonstrating a pIC50 of 9.8 against the human NK1 receptor in IM-9 cells. It exhibits anxiolytic and antidepressant-like effects, as evidenced in studies [1] [2].</p>Formula:C20H25Cl2F3N2O2Colore e forma:SolidPeso molecolare:453.33UDM-001651
CAS:<p>UDM-001651: oral PAR4 antagonist, IC50=4 nM, Kd=1.4 nM, antiplatelet IC50=25 nM in γ-thrombin assay.</p>Formula:C28H23N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:513.56SB-414796
CAS:<p>SB-414796 is a selective antagonist of the dopamine D3 receptor.</p>Formula:C29H36N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:536.6920-ethyl Prostaglandin E2
CAS:<p>20-Ethyl Prostaglandin E2 (20-ethyl PGE2) is an analog of Prostaglandin E2 (PGE2) characterized by an extended ω-chain due to two additional methylene carbon atoms. Compared to unoprostone, a clinically approved glaucoma medication and the only extensively studied prostaglandin analog sharing this structural modification, 20-ethyl PGE2 maintains the natural 15(S) allylic hydroxyl in its lower side chain, potentially enhancing its effectiveness. Unoprostone, despite being an F-series prostaglandin, exhibits reduced affinity for FP receptors because of its lower side chain modifications (13,14-dihydro-15-keto), which diminishes its medicinal potency. Notably, 20-ethyl PGE2's efficacy relative to unoprostone and its interaction with EP or other prostanoid receptors remains unconfirmed due to the lack of published ligand binding assays. E-type prostaglandins, including 20-ethyl PGE2, are broadly acknowledged for their inflammatory, cytoprotective, and diverse biological activities.</p>Formula:C22H36O5Colore e forma:SolidPeso molecolare:380.5Fiduxosin
CAS:<p>Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki</p>Formula:C30H29N5O4SPurezza:99.73%Colore e forma:SolidPeso molecolare:555.65PSB 0788
CAS:<p>adenosine A2B receptor antagonist</p>Formula:C25H27ClN6O4SPurezza:98%Colore e forma:SolidPeso molecolare:543.04L-054,522
CAS:<p>L-054,522 is potent, selective agonists of somatostatin receptor.</p>Formula:C35H47N7O5Colore e forma:SolidPeso molecolare:645.7917-phenyl trinor Prostaglandin E2
CAS:<p>17-Phenyl trinor Prostaglandin E2 (17-phenyl trinor PGE2) is a synthetic analog of PGE2, functioning as an agonist at the EP1 and EP3 receptors. It induces contraction of the guinea pig ileum at a 11 µM concentration and displays slightly less potency than PGE2 in stimulating the gerbil colon and rat uterus. Notably, with an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 exhibits 4.4 times greater antifertility efficacy in hamsters compared to PGE2.</p>Formula:C23H30O5Colore e forma:SolidPeso molecolare:386.5Z1078601926
CAS:<p>Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].</p>Formula:C14H19FN2OColore e forma:SolidPeso molecolare:250.31DORA 42
CAS:<p>DORA 42 is a dual antagonist of the orexin receptor OX1R and OX2R.</p>Formula:C22H24N8OSPurezza:98%Colore e forma:SolidPeso molecolare:448.54LAS191859
CAS:<p>LAS191859, a CRTH2 antagonist, IC50: 7.6-15.5nM across species, 21h half-life for sustained in vivo effect.</p>Formula:C24H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:459.46GRK2 Inhibitor 2
CAS:<p>GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances β-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293</p>Formula:C19H16N4O2Colore e forma:SolidPeso molecolare:332.36SC-50605
CAS:<p>SC-50605 is a second-generation LTB4 receptor antagonist.</p>Formula:C30H35NO6SColore e forma:SolidPeso molecolare:537.67Sigma-2 receptor antagonist 1
CAS:<p>Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor.</p>Formula:C24H33NO4SPurezza:98%Colore e forma:SolidPeso molecolare:431.59Tedalinab
CAS:<p>Tedalinab is an effective and selective cannabinoid receptor 2 agonist.</p>Formula:C19H21F2N3OPurezza:98%Colore e forma:SolidPeso molecolare:345.39mPGES1-IN-3
CAS:<p>mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .</p>Formula:C24H16ClF5N4O3Purezza:98%Colore e forma:SolidPeso molecolare:538.85TCS 2510
CAS:<p>TCS 2510 (CAY10598) 是一种选择性 PGE2 和 EP4 受体激动剂，可增强细胞内 cAMP 浓度和活性 β-caten 的丰度。TCS 2510 抑制TNF-α 产生，可用于研究代谢紊乱带来的疾病。</p>Formula:C21H29N5O2Purezza:98%Colore e forma:SolidPeso molecolare:383.49RS 17053 hydrochloride
CAS:<p>RS 17053 hydrochloride: selective α1A adrenoceptor antagonist, pKi 9.1, pA2 9.8.</p>Formula:C24H30Cl2N2O2Purezza:99.27%Colore e forma:SolidPeso molecolare:449.41TM-N1324
CAS:<p>TM-N1324 is a GPR39 agonist; 280 nM potency without Zn2+, 9 nM with; similar effects on murine GPR39 (EC50s: 180 nM/5 nM).</p>Formula:C18H13ClFN7OPurezza:99.88%Colore e forma:SolidPeso molecolare:397.794-Amino-PPHT Hydrobromide
CAS:<p>4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.</p>Formula:C21H28N2OPurezza:98%Colore e forma:SolidPeso molecolare:324.46CP-293019
CAS:<p>CP-293019 is a potent, selective antagonist of dopamine D4 receptor.</p>Formula:C19H22F2N4OPurezza:98%Colore e forma:SolidPeso molecolare:360.4RG 14893
CAS:<p>RG 14893 is a antagonist of high-affinity leukotriene B4 receptor.</p>Formula:C29H27NO4Purezza:98%Colore e forma:SolidPeso molecolare:453.53JNJ-19567470
CAS:<p>JNJ-19567470 is a selective, non-peptide CRF receptor 1 antagonist.</p>Formula:C22H27BrN4OColore e forma:SolidPeso molecolare:443.38
