Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.024 prodotti)
- Recettore dell'adenosina(249 prodotti)
- Recettore adrenergico(3.030 prodotti)
- Recettore della bombesina(35 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(159 prodotti)
- CaSR(34 prodotti)
- Recettore dei cannabinoidi(217 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(443 prodotti)
- Recettore dell'endotelina(86 prodotti)
- Recettore GNRH(84 prodotti)
- GPCR19(33 prodotti)
- GRK(33 prodotti)
- GTPase(22 prodotti)
- Recettore del glucagone(196 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(385 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(326 prodotti)
- PAFR(14 prodotti)
- PKA(54 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
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Trovati 5981 prodotti di "Proteina G/GPCR"
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CI-988
CAS:CCK2 (CCK-B) receptor antagonistFormula:C35H42N4O6Purezza:98%Colore e forma:SolidPeso molecolare:614.73BMS-741672
CAS:BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.Formula:C25H33F3N6O2Colore e forma:SolidPeso molecolare:506.56Revexepride
CAS:Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Formula:C21H32ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:425.95MK-8318
CAS:MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Formula:C27H26F4N2O5Purezza:98%Colore e forma:SolidPeso molecolare:534.5Henagliflozin
CAS:Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.Formula:C22H24ClFO7Colore e forma:SolidPeso molecolare:454.87GRK6-IN-5
CAS:GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.Formula:C23H21N3O2Colore e forma:SolidPeso molecolare:371.432PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Formula:C24H30N6O4Colore e forma:SolidPeso molecolare:466.53BI 703704
CAS:BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].Formula:C32H37N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:559.72AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColore e forma:SolidPeso molecolare:268.78Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Formula:C15H9NaO5SColore e forma:SolidPeso molecolare:324.28L-654284
CAS:L-654284 is an α2-adrenergic receptor antagonist characterized by its notable selectivity. It competes with 3H-clonidine and 3H-rauwolscine for binding in vitro, exhibiting Ki values of 0.8 nM and 1.1 nM, respectively. L-654284 effectively blocks the pre-ejaculatory effects of clonidine in isolated rat vas deferens, with a pA2 value of 9.1. The compound demonstrates significant selectivity for α2 over α1 adrenergic receptors, with a Ki value of 110 nM against 3H-prazosin binding. In vivo, L-654284 significantly increases the turnover of norepinephrine in the rat cerebral cortex, indicating its activity in blocking α2-adrenergic receptors within the central nervous system.Formula:C18H24N2O4SColore e forma:SolidPeso molecolare:364.46BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Formula:C25H37N3O5Colore e forma:SolidPeso molecolare:459.58Methacycline
CAS:<p>Methacycline, a tetracycline antibiotic, inhibits bacterial protein synthesis and effectively suppresses epithelial-mesenchymal transition (EMT). It blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting the TGF-β1Smad signaling pathway. As an antimicrobial agent, Methacycline holds potential for research in pulmonary fibrosis.</p>Formula:C22H22N2O8Colore e forma:SolidPeso molecolare:442.42GLP-1R agonist 8
CAS:GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formula:C33H32N4O5Colore e forma:SolidPeso molecolare:564.63LPA2 antagonist 5
CAS:LPA2 antagonist 5 (EX1) functions as an antagonist of LPA2, with an IC50 value of 4.05 nM.Formula:C17H17F3N2O5Colore e forma:SolidPeso molecolare:386.323Abarelix acetate
CAS:Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.Formula:C72H95ClN14O14·xC2H4O2Colore e forma:SolidPeso molecolare:1476.14SSTR5 antagonist 2 hydrochloride
SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.Formula:C32H36ClFN2O5Colore e forma:SolidPeso molecolare:583.09NMDAR antagonist 5
CAS:NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.Formula:C17H21N3Colore e forma:SolidPeso molecolare:267.369Pexacerfont
CAS:Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).Formula:C18H24N6OPurezza:99.77%Colore e forma:SolidPeso molecolare:340.42GPR27 agonist-1
CAS:GPR27 agonist-1 (compound I) is a selective agonist for GPR27 with a pEC50 value of 6.34.Formula:C19H14Cl2N2O3SColore e forma:SolidPeso molecolare:421.30Inupadenant HCl
CAS:Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.Formula:C25H27ClF2N8O4S2Colore e forma:SolidPeso molecolare:641.11BIIE-0246 HCl
CAS:BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.Formula:C49H59Cl2N11O6Colore e forma:SolidPeso molecolare:968.97TAK-661
CAS:TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.Formula:C13H21N5O3SColore e forma:SolidPeso molecolare:327.40DMPX
CAS:DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine-like compound capable of crossing the blood-brain barrier. It serves as an A2-selective adenosine receptor (AR) antagonist, effectively and selectively blocking the hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists, such as NECA. DMPX is utilized in research on diseases like Parkinson's disease.Formula:C10H10N4O2Colore e forma:SolidPeso molecolare:218.212Mafoprazine
CAS:Mafoprazine, a phenylpiperazine derivative, exhibits varying affinities for neuronal receptors, primarily exerting its antipsychotic effects through blocking D2 receptors and enhancing α-adrenergic activity. It also increases the activity of dopamine metabolites.Formula:C22H28FN3O3Colore e forma:SolidPeso molecolare:401.47Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Formula:C19H17NNaO7Purezza:98%Colore e forma:SolidPeso molecolare:394.335Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formula:C25H30N2O7Purezza:98%Colore e forma:SolidPeso molecolare:470.51YNT-3708
CAS:YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.Formula:C35H36N4O6SColore e forma:SolidPeso molecolare:640.749UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Formula:C40H47N11O6Colore e forma:SolidPeso molecolare:777.87AH22921
CAS:AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.Formula:C29H35NO5Colore e forma:SolidPeso molecolare:477.59Mrgx2 antagonist-3
CAS:<p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>Formula:C15H15F2N3OColore e forma:SolidPeso molecolare:291.30LP 12 hydrochloride hydrate
LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.Formula:C32H39N3O·HCl·xH2OColore e forma:SolidRocavorexant
CAS:Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.Formula:C18H19F3N8OColore e forma:SolidPeso molecolare:420.392LK 11
CAS:LK-11, an alkaloid derivative, inhibits the passive uptake of norepinephrine (NA) by synaptic vesicles in the thalamus, similarly to cocaine.Formula:C15H26N2O3Colore e forma:SolidPeso molecolare:282.38Beloxepin
CAS:Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Formula:C19H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:295.38RBM10-8
CAS:RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.Formula:C17H36NO5PColore e forma:SolidPeso molecolare:365.45SB 258741 hydrochloride
SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].Formula:C19H31ClN2O2SColore e forma:SolidPeso molecolare:386.98(Rac)-BI 703704
CAS:(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).Formula:C32H37N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:559.72YM158 free base
CAS:YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).Formula:C32H33ClN6O5S2Purezza:98%Colore e forma:SolidPeso molecolare:681.22SGLT1/2-IN-1
CAS:SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.Formula:C25H28O8Colore e forma:SolidPeso molecolare:456.48SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formula:C25H34N4O7SPurezza:99.09% - 99.91%Colore e forma:SolidPeso molecolare:534.63Ophiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Formula:C25H38O3Purezza:98%Colore e forma:SolidPeso molecolare:386.57S1PR1 agonist 2
CAS:S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).Formula:C25H25N5O4Colore e forma:SolidPeso molecolare:459.50BI-685509
CAS:BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.Formula:C34H38N4O5Colore e forma:SolidPeso molecolare:582.69Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formula:C20H26N4OColore e forma:SolidPeso molecolare:338.45CVT-5440
CAS:CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.Formula:C27H28N6O5Colore e forma:SolidPeso molecolare:516.55Disulergine
CAS:Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.Formula:C17H24N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:348.468-iso Prostaglandin F3α
CAS:8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.Formula:C20H32O5Colore e forma:SolidPeso molecolare:352.47RS 61756-007
CAS:RS 61756-007 is a selective thromboxane receptor (TP) agonist.Formula:C23H28O5Purezza:98%Colore e forma:SolidPeso molecolare:384.47Fasitibant
CAS:Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.Formula:C36H49Cl2N6O6SColore e forma:SolidPeso molecolare:764.78GLP-1 receptor agonist 16
CAS:GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Formula:C33H31ClFN3O4Colore e forma:SolidPeso molecolare:588.068MRS2279 diammonium
CAS:MRS2279 diammonium, a P2Y1 antagonist with K i 2.5 nM, IC 50 51.6 nM, blocks ADP-induced platelet aggregation, pK b 8.05.Formula:C13H24ClN7O8P2Colore e forma:SolidPeso molecolare:503.77H3R antagonist 2
Compound 23: H3R antagonist with 170 nM Ki; inhibits AChE, BChE, hMAO B; IC50s: 180, 880, 775 nM; anti-pain, memory boost; crosses BBB. [1]Formula:C24H29NO3Colore e forma:SolidPeso molecolare:379.49AL 6598
CAS:AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.Formula:C23H39ClO5Colore e forma:SolidPeso molecolare:431.01Dopamine D3 receptor antagonist-2
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.Formula:C23H27Cl2N3O3Colore e forma:SolidPeso molecolare:464.38Pareptide monohydrochloride
CAS:Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).Formula:C14H27ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:334.84(S)-Praziquantel
CAS:(S)-Praziquantel is the inactive isomer of R-praziquantel.Formula:C19H24N2O2Colore e forma:SolidPeso molecolare:312.406L-796778 acetate
CAS:L-796778 acetate is a selective sst3 receptor agonist. In CHO-K1 cells expressing hsst3 receptors, it acts as a partial agonist that inhibits Forskolin-induced cAMP production, with an IC50 value of 18 nM. Additionally, L-796778 acetate exhibits anticonvulsant properties.Formula:C31H44N6O9Colore e forma:SolidPeso molecolare:644.716BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Colore e forma:SolidPeso molecolare:633.78Rivenprost
CAS:Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formula:C24H34O6SColore e forma:SolidPeso molecolare:450.59RF9 hydrochloride
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).Formula:C26H39ClN6O3Colore e forma:SolidPeso molecolare:519.08Apafant
CAS:Apafant (WEB 2086) is a PAF antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.Formula:C22H22ClN5O2SPurezza:99.56%Colore e forma:SolidPeso molecolare:455.96Ref: TM-T14300
1mg67,00€5mg156,00€10mg243,00€25mg479,00€50mgPrezzo su richiesta1mL*10mM (DMSO)157,00€FK-3657
CAS:FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.Formula:C30H27Cl2N5O4Colore e forma:SolidPeso molecolare:592.47(R)-MrgprX2 antagonist-3
CAS:(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.Formula:C16H20FN3O2SPeso molecolare:337.41CB1/2 agonist 1
Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.Formula:C21H24BrFN2O2Colore e forma:SolidPeso molecolare:435.33NK-1 Antagonist 1
CAS:NK-1 Antagonist 1 is a NK-1 receptor antagonist.Formula:C25H23F6N5O2Purezza:98%Colore e forma:SolidPeso molecolare:539.47PAR4 antagonist 3
CAS:PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.Formula:C22H16FN3O5SPeso molecolare:453.44TAK-637
CAS:TAK-637 is a tachykinin 1 (NK1) receptor antagonist.Formula:C30H25F6N3O2Purezza:98%Colore e forma:SolidPeso molecolare:573.53U91356
CAS:U91356 is an agonist of the dopamine receptors.Formula:C13H17N3OPurezza:98%Colore e forma:SolidPeso molecolare:231.29Burapitant
CAS:<p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>Formula:C31H35Cl2F6N3O3Purezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:682.52GPBAR1-IN-3
CAS:GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].Formula:C21H23NO2Colore e forma:SolidPeso molecolare:321.41WIN 66306
CAS:WIN 66306: Cyclic heptapeptide, blocks NK1/NK2 receptors, inhibits substance P-triggered contractions in guinea pig ileum.Formula:C41H52N8O9Colore e forma:SolidPeso molecolare:800.9MRS2905 trisodium
CAS:MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. It shows no activity on UDP-activated P2Y6 receptors or other P2Y receptors.Formula:C10H13N2Na3O10P2SColore e forma:SolidPeso molecolare:484.199Becondogrel
CAS:Becondogrel (2-Oxoclopidogrel) is a metabolite of Clopidogrel. It irreversibly inhibits the P2Y12 receptor, thereby preventing platelet aggregation and thrombosis.Formula:C16H16ClNO3SColore e forma:SolidPeso molecolare:337.821Terguride
CAS:Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.Formula:C20H28N4OColore e forma:SolidPeso molecolare:340.46CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurezza:98%Colore e forma:SolidPeso molecolare:673.65Leukotriene B4 dimethyl amide
CAS:LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).Formula:C22H37NO3Colore e forma:SolidPeso molecolare:363.53Danavorexton
CAS:Danavorexton is an orexin receptor agonist.Formula:C21H32N2O5SColore e forma:SolidPeso molecolare:424.55CP-608039
CAS:CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.Formula:C23H25ClN8O5Colore e forma:SolidPeso molecolare:528.95Taprostene
CAS:Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.Formula:C24H30O5Colore e forma:SolidPeso molecolare:398.49Merigolix
CAS:Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist .Formula:C36H35F7N4O6Colore e forma:SolidPeso molecolare:752.68Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Formula:C24H28F3N3O2Colore e forma:SolidPeso molecolare:447.49BD-1047
CAS:BD-1047 is a selective functional antagonist of sigma receptors. It can alleviate climbing behavior induced by Apomorphine and head twitching caused by Phencyclidine.Formula:C13H20Cl2N2Colore e forma:SolidPeso molecolare:275.2175-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formula:C9H14N4Colore e forma:SolidPeso molecolare:178.234L-657926
CAS:L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid. The IC50 values for the (-) and (+) configurations against TxA2 are 0.27 nM and 124 nM, respectively.Formula:C21H19ClFNO2Colore e forma:SolidPeso molecolare:371.832KAG-308
CAS:KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.Formula:C24H30F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:460.52LPA2 antagonist 6
CAS:LPA2 antagonist 6 (example 2) acts as an antagonist of Lp(a). It inhibits the formation of Lp(a) with an IC50 value of 2.33 nM, making it useful for cardiovascular disease research.Formula:C26H34Cl2N2O6Colore e forma:SolidPeso molecolare:541.464Taranabant
CAS:Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.Formula:C27H25ClF3N3O2Purezza:99.06% - 99.06%Colore e forma:SolidPeso molecolare:515.96LPA receptor antagonist-1
CAS:LPA receptor antagonist-1 (example 52) serves as an antagonist for the lysophosphatidic acid (LPA) receptor and is applicable in various types of studies [1].Formula:C30H26ClNO5SPeso molecolare:548.05A1AR antagonist 1
Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).Formula:C18H14N4OColore e forma:SolidPeso molecolare:302.33GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Formula:C31H31FN6O4Peso molecolare:570.61Sigma-1 receptor antagonist 6
CAS:Sigma-1 receptor antagonist 6 (Compound 12), a σ1R antagonist, demonstrates significant antiallodynic effects by targeting the Sigma-1 receptor (σ1R). This compound is effective in animal models for neuropathic pain, particularly for reducing mechanical allodynia caused by paclitaxel.Formula:C32H34N6Colore e forma:SolidPeso molecolare:502.65CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Colore e forma:SolidMK-3207
CAS:MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.Formula:C31H29F2N5O3Colore e forma:SolidPeso molecolare:557.59CHF-6366
CAS:CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.Formula:C42H48N6O8Colore e forma:SolidPeso molecolare:764.87PD 140376
CAS:PD 140376: Selective CCK-B/gastrin receptor antagonist radioligand for guinea pig stomach & brain.Formula:C33H40N4O5Purezza:98%Colore e forma:SolidPeso molecolare:572.6912(S)-HEPE
CAS:12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.45Nedemelteon
CAS:Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).Formula:C15H18N2O2Colore e forma:SolidPeso molecolare:258.32SAR-150640
CAS:SAR-150640, a selective β3-adrenergic receptor agonist, prevents an increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis.Formula:C25H35ClN2O7SColore e forma:SolidPeso molecolare:543.07Neflumozide
CAS:Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.Formula:C22H23FN4O2Colore e forma:SolidPeso molecolare:394.44Sigma-2 Radioligand 2
CAS:Sigma-2 Radioligand 2 (compound 4) exhibits low nanomolar affinity for the σ2 receptor (Ki=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500).Formula:C23H28FN3O3Colore e forma:SolidPeso molecolare:413.49Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Formula:C20H21N3O2Colore e forma:SolidPeso molecolare:335.40CB1/2 receptor-1
CAS:CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.Formula:C33H48O2Colore e forma:SolidPeso molecolare:476.73AzoLPA ammonium
CAS:AzoLPA ammonium is a photoswitchable lipid that activates signaling of lysophosphatidic acid receptors 1-5 (LPA1-5).Formula:C23H34N3O7PColore e forma:SolidPeso molecolare:495.51hA3AR agonist 1
hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .Formula:C10H14N6OSColore e forma:SolidPeso molecolare:266.32GLP-1R agonist 32
CAS:GLP-1R agonist 32 (Compound 111) is an orally active and potent GLP-1R agonist with an EC50 value of 0.017 nM. It stimulates the production of cyclic adenosine monophosphate (cAMP) by activating GLP-1R, which enhances insulin secretion, suppresses glucagon release, and delays gastric emptying to regulate blood glucose levels. GLP-1R agonist 32 shows potential for research in type 2 diabetes, obesity, and related metabolic disorders.Formula:C32H31ClFN3O5Colore e forma:SolidPeso molecolare:592.0616(R)-Iloprost
CAS:Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49Neladenoson
CAS:Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.Formula:C29H24ClN5O2S2Colore e forma:SolidPeso molecolare:574.12AM9405
AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.Formula:C24H33BrN2O2Purezza:98%Colore e forma:SolidPeso molecolare:461.44GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formula:C30H28F4N6O5Peso molecolare:628.57SSR 146977 hydrochloride
CAS:SSR 146977 hydrochloride is a potent, selective antagonist of the tachykinin NK 3 receptor, and it can be utilized in research on psychiatric disorders and airway inflammation [1].Formula:C35H43Cl3N4O2Peso molecolare:658.1Jimscaline
CAS:Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formula:C13H19NO3Peso molecolare:237.295S1P1 agonist 4
CAS:S1P1 agonist 4 exhibits enhanced potency with an EC 50 value of less than 0.05 mg/kg and a predicted human half-life (t1/2) of approximately 5 days, indicatingFormula:C24H31NO3Colore e forma:SolidPeso molecolare:381.51AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Colore e forma:SolidPeso molecolare:395.53BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purezza:98.43% - 99.26%Colore e forma:SolidPeso molecolare:561.63Dersimelagon
CAS:Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.Formula:C36H45F4N3O5Purezza:97.35% - 98.23%Colore e forma:SolidPeso molecolare:675.75SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formula:C26H32N2O4Purezza:99.22%Colore e forma:SolidPeso molecolare:436.54Ref: TM-T12846
1mg37,00€5mg80,00€10mg119,00€25mg210,00€50mg319,00€100mg442,00€200mg605,00€1mL*10mM (DMSO)89,00€SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purezza:98.99% - 99.96%Colore e forma:SolidPeso molecolare:557.08Ref: TM-T12841
1mg42,00€5mg88,00€10mg115,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)101,00€Vofopitant
CAS:Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formula:C21H23F3N6OPurezza:97.86%Colore e forma:SolidPeso molecolare:432.44AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formula:C32H38F2N2O5S2Purezza:98.1%Colore e forma:SolidPeso molecolare:632.78Ref: TM-T30260
1mg202,00€5mg459,00€10mg643,00€25mg938,00€50mg1.311,00€100mg1.786,00€1mL*10mM (DMSO)560,00€LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Formula:C26H23Cl2N3O2Purezza:99.21%Colore e forma:SolidPeso molecolare:480.39AZD5462
CAS:AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.Formula:C30H41FN2O6Purezza:98.32% - 99.63%Colore e forma:SolidPeso molecolare:544.65Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formula:C21H25Cl2F3N6OPurezza:98.99%Colore e forma:SolidPeso molecolare:505.36Ref: TM-T13329L
1mg99,00€5mg235,00€10mg376,00€25mg712,00€50mg1.064,00€100mg1.454,00€500mg2.822,00€1mL*10mM (DMSO)261,00€PF-07258669
CAS:PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.Formula:C25H27FN6O2Purezza:99.9%Colore e forma:SolidPeso molecolare:462.52BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purezza:98.81%Colore e forma:SolidPeso molecolare:641.8Ref: TM-T10595
1mg137,00€2mg188,00€5mg329,00€10mg472,00€25mg753,00€50mg1.017,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)360,00€Treprostinil diethanolamine
CAS:Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,Formula:C27H45NO7Purezza:99.86%Colore e forma:SolidPeso molecolare:495.65Rolapitant hydrochloride
CAS:Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.Formula:C25H27ClF6N2O2Purezza:98.35% - 99.79%Colore e forma:SolidPeso molecolare:536.94Ref: TM-T3724
1mg153,00€5mg365,00€10mg520,00€25mg780,00€50mg1.054,00€100mg1.425,00€200mg1.882,00€1mL*10mM (DMSO)439,00€SR 146131
CAS:SR 146131 is a potent and selective agonist of the nonpeptide receptor.Formula:C32H36ClN3O5SPurezza:98%Colore e forma:SolidPeso molecolare:610.16JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Formula:C30H32N6O2Colore e forma:SolidPeso molecolare:508.61CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Formula:C27H31N3O3S2Colore e forma:SolidPeso molecolare:509.687-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formula:C14H15NO2Colore e forma:SolidPeso molecolare:229.27BIBP3226 TFA
CAS:BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).Formula:C29H32F3N5O5Colore e forma:SolidPeso molecolare:587.59Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Formula:C24H29NaO5Colore e forma:SolidPeso molecolare:420.481HOKU-81
CAS:HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.Formula:C12H18ClNO2Colore e forma:SolidPeso molecolare:243.73Protease-Activated Receptor-4
CAS:Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formula:C33H46N8O7Purezza:98%Colore e forma:SolidPeso molecolare:666.77ML-00253764 hydrochloride
CAS:ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).Formula:C18H19BrClFN2OColore e forma:SolidPeso molecolare:413.71SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formula:C18H22Cl3N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:482.81ML-290
CAS:ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.Formula:C24H21F3N2O5SColore e forma:SolidPeso molecolare:506.49SHA 68
CAS:SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.Formula:C26H24FN3O3Purezza:98%Colore e forma:SolidPeso molecolare:445.49Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Colore e forma:White SolidPeso molecolare:371.54Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:339.84N-methyl-2-AI (hydrochloride)
CAS:N-methyl-2-AI (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T66396 and the CAS number is 10408-85-2.Formula:C10H14ClNColore e forma:SolidPeso molecolare:183.68Amelubant
CAS:Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.Formula:C33H34N2O5Purezza:98%Colore e forma:SolidPeso molecolare:538.63Vornorexant
CAS:Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Formula:C23H22FN7O2Colore e forma:SolidPeso molecolare:447.474Picumeterol
CAS:Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.Formula:C21H29Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:426.38TAK-448
CAS:TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.Formula:C58H80N16O14Purezza:98%Colore e forma:SolidPeso molecolare:1225.36GSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Colore e forma:Odour Liquid3-Hydroxybenzylamine
CAS:3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.Formula:C7H9NOColore e forma:SolidPeso molecolare:123.155TAK-683
CAS:TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.Formula:C64H83N17O13Purezza:98%Colore e forma:SolidPeso molecolare:1298.45CRTh2 antagonist 3
CAS:CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.Formula:C19H20N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:356.446-Chloro-5-(2-chloroethyl)indolin-2-one
CAS:6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.Formula:C10H9Cl2NOColore e forma:SolidPeso molecolare:230.09Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Colore e forma:Odour LiquidPatecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purezza:98%Colore e forma:LiquidRef: TM-T81538
Prodotto fuori produzioneBX471 hydrochloride
CAS:BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Formula:C21H25Cl2FN4O3Purezza:98%Colore e forma:SolidPeso molecolare:471.35Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formula:C22H21FN2OColore e forma:SolidPeso molecolare:348.421SKF 89748
CAS:SKF 89748 is an agonists of alpha 1-adrenoceptor.Formula:C12H17NOSPurezza:98%Colore e forma:SolidPeso molecolare:223.331-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol
CAS:1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol is a useful organic compound for research related to life sciences. The catalog number is T65156 and the CAS number is 24155-42-8.Formula:C11H10Cl2N2OColore e forma:SolidPeso molecolare:257.11dapitant
CAS:Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.Formula:C37H39NO4Colore e forma:SolidPeso molecolare:561.714-Hydroxyatomoxetine
CAS:4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.Formula:C17H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:271.35Desmethyl cariprazine
CAS:Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formula:C20H30Cl2N4OPurezza:98%Colore e forma:SolidPeso molecolare:413.38(R)-(-)-α-Methylhistamine dihydrochloride
CAS:R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formula:C6H13Cl2N3Colore e forma:SolidPeso molecolare:198.09(Rac)-Zevaquenabant
CAS:(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Formula:C25H21ClF3N5O2SColore e forma:SolidPeso molecolare:547.98Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Purezza:99.77%Colore e forma:Odour Solid4-Hydroxypropranolol hydrochloride
CAS:4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).Formula:C16H22ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:311.8Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Formula:C16H25N3O·xClHPurezza:99.25%Colore e forma:Soild1-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Formula:C21H41O7PColore e forma:SolidPeso molecolare:436.52BRL 15572
CAS:BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formula:C25H27ClN2OColore e forma:SolidPeso molecolare:406.95Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Formula:C24H25FO5SPurezza:98%Colore e forma:SolidPeso molecolare:448.54Ref: TM-T10669
Prodotto fuori produzione2-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H15ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:226.7Ref: TM-T10075L2
Prodotto fuori produzioneRU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Colore e forma:SolidPeso molecolare:346.38Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Formula:C23H16O6Purezza:99.99%Colore e forma:Fine Yellow PowderPeso molecolare:388.37MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Formula:C38H40N4O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:600.75Neurokinin antagonist 1
CAS:Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Formula:C38H40N4O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:600.75SB251023
CAS:SB251023 is an agonist of β3-adrenoceptor.Formula:C28H34NO6PColore e forma:SolidPeso molecolare:511.55Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formula:C11H12F3NOPurezza:98%Colore e forma:SolidPeso molecolare:231.21Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formula:C6H12Br2N4SPurezza:98%Colore e forma:SolidPeso molecolare:332.06GR 218,231
CAS:GR 218,231 is a selective antagonist of D3 dopamine receptor.Formula:C24H33NO3SPurezza:98%Colore e forma:SolidPeso molecolare:415.59Ref: TM-T27431
Prodotto fuori produzioneS1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purezza:98%Colore e forma:SolidPeso molecolare:445.47AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purezza:99.58%Colore e forma:SolidPeso molecolare:436.632-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Formula:C8H8N2O3SColore e forma:LiquidPeso molecolare:212.23Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:470.73Ref: TM-T27176
Prodotto fuori produzione
