Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.024 prodotti)
- Recettore dell'adenosina(249 prodotti)
- Recettore adrenergico(3.030 prodotti)
- Recettore della bombesina(35 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(159 prodotti)
- CaSR(34 prodotti)
- Recettore dei cannabinoidi(217 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(443 prodotti)
- Recettore dell'endotelina(86 prodotti)
- Recettore GNRH(84 prodotti)
- GPCR19(33 prodotti)
- GRK(33 prodotti)
- GTPase(22 prodotti)
- Recettore del glucagone(196 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(385 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(326 prodotti)
- PAFR(14 prodotti)
- PKA(54 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
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Trovati 5981 prodotti di "Proteina G/GPCR"
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Mesulergine hydrochloride
CAS:5-HT2A and 2C receptor antagonistFormula:C18H27ClN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:398.95GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Colore e forma:SolidPeso molecolare:558.59CCR3 antagonist 2
CAS:CCR3 antagonist2 (example 66) is a CCR3 antagonist useful for researching inflammatory or allergic diseases, particularly those affecting the respiratory tract, such as inflammatory or obstructive airway conditions.Formula:C21H28ClN5O3Colore e forma:SolidPeso molecolare:433.93ADORA2A/PDE4D-IN-1
CAS:ADORA2A/PDE4D-IN-1 (Compound 9) is a dual inhibitor of the adenosine A2a receptor (ADORA2A) and phosphodiesterase 4D (PDE4D). This compound is applicable for research in bronchial asthma.Formula:C14H11N5Colore e forma:SolidPeso molecolare:249.271O-1269
CAS:O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.Formula:C22H22Cl3N3OColore e forma:SolidPeso molecolare:450.79S1P1 agonist 5
Selective oral S1P1 agonist 5 inhibits lymphocyte drainage, potential for MS research.Formula:C23H24ClN2NaO4Colore e forma:SolidPeso molecolare:450.89AB-FUBINACA 3-fluorobenzyl isomer
CAS:AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.Formula:C20H21FN4O2Colore e forma:SolidPeso molecolare:368.41CVN766
CAS:CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and >10 μM for OX2R. CVN766 can be used to study schizophrenia [1].Formula:C20H21F3N8OColore e forma:SolidPeso molecolare:446.43Hoe 892
CAS:Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.Formula:C20H33NO4SColore e forma:SolidPeso molecolare:383.55ATL444
CAS:ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and >1000 nM, respectively.Formula:C17H19N5OColore e forma:SolidPeso molecolare:309.375-HT1A antagonist 1
Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.Formula:C23H29ClN6O2Colore e forma:SolidPeso molecolare:456.97R-137696
CAS:R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.Formula:C17H23N3O2Colore e forma:SolidPeso molecolare:301.38Bometolol Hydrochloride
CAS:Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.Formula:C25H33ClN2O7Purezza:98%Colore e forma:SolidPeso molecolare:508.99A3AR antagonist 5
CAS:A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.Formula:C18H16N2O2SColore e forma:SolidPeso molecolare:324.40Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Formula:C22H33FN2O2Colore e forma:SolidPeso molecolare:376.51AGH-107
CAS:AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.Formula:C13H12IN3Colore e forma:SolidPeso molecolare:337.16Butopamine hydrochloride
CAS:Butopamine hydrochloride is an orally active inotropic compound that is more effective at increasing heart rate compared to Dobutamine.Formula:C18H24ClNO3Colore e forma:SolidPeso molecolare:337.84Dinoxyline
CAS:Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.Formula:C15H13NO3Colore e forma:SolidPeso molecolare:255.27Elzasonan hydrochloride
CAS:Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.Formula:C22H24Cl3N3OSColore e forma:SolidPeso molecolare:484.87Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Formula:C16H20N2O2SColore e forma:SolidPeso molecolare:304.41Sulfinalol hydrochloride
CAS:Sulfinalol hydrochloride is an orally active β-adrenoceptor (β-adrenoceptor) antagonist that exhibits direct vasodilatory activity. It is also classified as an antihypertensive agent.Formula:C20H28ClNO4SColore e forma:SolidPeso molecolare:413.96BRD50837
CAS:BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).Formula:C26H32ClN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:550.07TGR5 Receptor Agonist 3
CAS:TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.Formula:C29H27N3O6Colore e forma:SolidPeso molecolare:513.54(±)-Penbutolol
CAS:(±)-Penbutolol ((Rac)-Penbutolol) is the racemic form of Penbutolol. It acts as an orally active β-adrenergic receptor antagonist. (±)-Penbutolol mitigates the tachycardia induced by exercise, reduces the increase in peak expiratory flow rate (PEFR) caused by physical activity, and decreases plasma renin activity (PRA) at rest. The peak plasma concentration of this compound is achieved one hour after oral administration, with a half-life of 4.5 hours, and it is metabolized into active metabolites in the body. This compound is utilized in research related to cardiovascular diseases.Formula:C18H29NO2Colore e forma:SolidPeso molecolare:291.43AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formula:C14H21BrN2OColore e forma:SolidPeso molecolare:313.23APJ receptor agonist 8
CAS:<p>APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts.</p>Formula:C24H27N7O5SPurezza:98.31% - 99.60%Colore e forma:SolidPeso molecolare:525.58AAZ-A 154 hydrochloride
CAS:AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formula:C14H21ClN2OColore e forma:SolidPeso molecolare:268.78AL 6598
CAS:AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.Formula:C23H39ClO5Colore e forma:SolidPeso molecolare:431.01CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Colore e forma:SolidBRL-37344
CAS:<p>BRL-37344 is a selective β3-adrenergic receptor agonist. It significantly reduces the body weight of obese mice.</p>Formula:C19H22ClNO4Colore e forma:SolidPeso molecolare:363.84CM699
CAS:CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.Formula:C24H29N3O2Colore e forma:SolidPeso molecolare:391.51SGLT1/2-IN-8
CAS:SGLT1/2-IN-8 (compound 8) is a potent and orally active dual inhibitor of SGLT1/2, exhibiting IC50 values of 4 nM and 1 nM, respectively. It shows antihyperglycemic properties, making it suitable for related research.Formula:C22H26O6Colore e forma:SolidPeso molecolare:386.438CRHR1 antagonist 1
CAS:CRHR1 antagonist 1 (compound 10a) is a non-peptide antagonist of corticotropin-releasing hormone receptor 1 (CRHR1). It serves as a useful tool in the study of psychiatric disorders.Formula:C24H34N4OColore e forma:SolidPeso molecolare:394.553Arpromidine
CAS:Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.Formula:C21H25FN6Colore e forma:SolidPeso molecolare:380.462Org 274179-0
CAS:<p>Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI)-mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of Graves' disease (GD).</p>Formula:C28H27F3N2O2Colore e forma:SolidPeso molecolare:480.521Opipramol dihydrochloride
CAS:Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).Formula:C23H31Cl2N3OColore e forma:SolidPeso molecolare:436.418Cicaprost
CAS:Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Formula:C22H30O5Colore e forma:SolidPeso molecolare:374.47Serotonin maleate
CAS:Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.Formula:C14H16N2O5Colore e forma:SolidPeso molecolare:292.287K-8794
CAS:K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.Formula:C36H38N6O6SColore e forma:SolidPeso molecolare:682.789Cendifensine
CAS:Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).Formula:C14H17Cl2NOColore e forma:SolidPeso molecolare:286.197SphK2-IN-1
CAS:SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.Formula:C23H22ClF3N8OColore e forma:SolidPeso molecolare:518.92PD 135158
CAS:PD 135158 is a CCK2 receptor antagonist.Formula:C42H61N5O11Purezza:98%Colore e forma:SolidPeso molecolare:811.96SR 142948-C3-NHMe
CAS:<p>SR 142948-C3-NHMe is the methylated form of SR 142948.</p>Formula:C42H58N6O6Colore e forma:SolidPeso molecolare:742.946GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formula:C28H32F3N5O4Colore e forma:SolidPeso molecolare:559.58N-methyl Leukotriene C4
CAS:N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.Formula:C31H49N3O9SColore e forma:SolidPeso molecolare:639.8K-14585
CAS:K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.Formula:C51H56Cl2N8O4Colore e forma:SolidPeso molecolare:915.95L-365260 hemihydrate
L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.Formula:C24H24N4O3Colore e forma:SolidPeso molecolare:407.47CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurezza:98%Colore e forma:SolidPeso molecolare:673.65Burapitant
CAS:<p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>Formula:C31H35Cl2F6N3O3Purezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:682.52Ro-24-4736
CAS:Ro 24-4736 is an effective and selective platelet-activating factor antagonist.Formula:C31H20ClN5OSPurezza:98%Colore e forma:SolidPeso molecolare:546.0425C-NBF hydrochloride
CAS:25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.Formula:C17H20Cl2FNO2Peso molecolare:360.251Dopamine D4 receptor ligand 3
CAS:Dopamine D4 receptor ligand 3 (Compound 16) functions as a dopamine D4 receptor (D4R) antagonist with a pKi of 8.86. In HEK-293T cells, it shows pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors, respectively. This compound inhibits the activity of human glioma cell lines U87 MG, T98G, and U251 MG, and it induces ROS production and mitochondrial dysfunction in these glioma cells.Formula:C28H31N3O5Colore e forma:SolidPeso molecolare:489.565-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Formula:C21H26N6SColore e forma:SolidPeso molecolare:394.54SLF1081851 hydrochloride
CAS:SLF1081851 (hydrochloride), a Spns2 inhibitor, effectively inhibits S1P release with an IC50 value of 1.93 μM. This compound is instrumental in the development and functioning of the immune system [1].Formula:C21H34ClN3OPeso molecolare:379.97SGL5213
CAS:SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Formula:C37H55N3O8Purezza:98%Colore e forma:SolidPeso molecolare:669.85(+)-15-epi Cloprostenol
CAS:(+)-15-epi Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF2α) and functions as a potent FP receptor agonist. The compound (+)-15-epi Cloprostenol is the 15(S) or 15β-hydroxy enantiomer of (+)-(+)-15-epi Cloprostenol. Compared to the 15(R)-(+)-15-epi Cloprostenol, this epimer exhibits significantly lower activity as an FP receptor ligand. However, the specific activity of this isomer remains inadequately studied.Formula:C22H29ClO6Peso molecolare:424.92CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFormula:C26H28Cl2N6OPurezza:98%Colore e forma:SolidPeso molecolare:511.45LPA5 antagonist 3
CAS:LPA5 antagonist 3 (Example 74), a lysophosphatidic acid receptor 5 (LPA5) antagonist, exhibits potent activity with an IC50 value of 170 nM. It is primarily utilized in the research of pain disorders and atherosclerosis [1].Formula:C24H20F3NO4Peso molecolare:443.42Dopamine D3 receptor antagonist-2
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.Formula:C23H27Cl2N3O3Colore e forma:SolidPeso molecolare:464.38PSB-KK1415
CAS:PSB-KK1415 is a selective agonist for the human orphan G protein-coupled receptor GPR18, with an EC50 of 19.1 nM.Formula:C24H23ClN6O2Peso molecolare:462.93Elsovaptan
CAS:Elsovaptan is an antagonist of the vasopressin receptor and is applicable for research in Alzheimer's disease.Formula:C19H20ClN5O2Colore e forma:SolidPeso molecolare:385.847SEP-363856 mesylate
CAS:SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.Formula:C10H17NO4S2Colore e forma:SolidPeso molecolare:279.38PD-147693
CAS:PD-147693 (compound II) is an active metabolite of the presynaptic dopamine autoreceptor agonist CI-1007, and it exhibits antipsychotic activity similar to CI-1007.Formula:C24H27NOPeso molecolare:345.477(S)-YNT-3708
CAS:<p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>Formula:C35H36N4O6SColore e forma:SolidPeso molecolare:640.749SPL-IN-1
CAS:SPL-IN-1 (compound C17) acts as a dual species inhibitor of sphingosine-1-phosphate lyase [1].Formula:C31H42N2O6S2Peso molecolare:602.8AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Colore e forma:SolidPeso molecolare:395.53CTW0404
CAS:CTW0404 is an effective positive allosteric modulator (PAM) of the 5-HT receptor, with promising implications for research into neuropsychiatric disorders.Formula:C21H33N3O2Peso molecolare:359.51(E/Z)-Ozagrel sodium
CAS:(E/Z)-Ozagrel (sodium) [(E/Z)-OKY-046 (sodium)] is a mixture of the EZ isomers of Ozagrel (sodium). It acts as a thromboxane A2 (TXA2) synthase inhibitor. As an antiplatelet agent, Ozagrel (sodium) selectively inhibits human platelet aggregation, with an IC50 of 53.12 μM.Formula:C13H11N2NaO2Colore e forma:SolidPeso molecolare:250.228(1R,2S,3R)-Aprepitant
CAS:<p>(1R,2S,3R)-Aprepitant (Compound ent-4) is a competitive antagonist of the human neurokinin-1 (NK-1) receptor. It holds potential for research in the treatment of nausea and vomiting related to cancer or postoperative conditions.</p>Formula:C23H21F7N4O3Colore e forma:SolidPeso molecolare:534.427CP-865569
CAS:CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.Formula:C22H26ClFN2O5SColore e forma:SolidPeso molecolare:484.969Sulamserod hydrochloride
CAS:Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formula:C19H29Cl2N3O5SColore e forma:SolidPeso molecolare:482.42Sulprostone
CAS:EP3 and EP1 receptor agonistFormula:C23H31NO7SPurezza:98%Colore e forma:White To Off-White SolidPeso molecolare:465.56RTIOXA-43
CAS:RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.Formula:C37H37N5O5SPurezza:99.17%Colore e forma:SolidPeso molecolare:663.79Ref: TM-T87345
1mg221,00€5mg545,00€10mg879,00€25mg1.696,00€50mg2.725,00€100mg3.686,00€1mL*10mM (DMSO)795,00€5-HT2A receptor agonist-8
CAS:5-HT2A receptor agonist-8 (compound 8) is a potent 5-HT2A receptor agonist with an EC50 of 0.6784 nM. It is suitable for research related to depression and bipolar disorder.Formula:C22H27N3OPeso molecolare:349.47MDMB-FUBICA
CAS:MDMB-FUBICA is a potent agonist of the cannabinoid receptors and exhibits psychoactive properties. It can be utilized in e-cigarettes.Formula:C23H25FN2O3Colore e forma:SolidPeso molecolare:396.455SphK2-IN-2
SphK2-IN-2 (21g) is a potent and selective inhibitor of SphK2 (IC50: 0.23 μM).Formula:C21H25ClN10OColore e forma:SolidPeso molecolare:468.94A2A receptor antagonist 2
A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).Formula:C25H28FN7O3Colore e forma:SolidPeso molecolare:493.53PGDM
CAS:PGD2 is involved in allergy, asthma, sleep, temperature regulation, inhibits clotting, and relaxes blood vessels; PGDM, its metabolite, is a biomarker.Formula:C16H24O7Colore e forma:SolidPeso molecolare:328.36Cloprostenol
CAS:Cloprostenol is a synthetic prostaglandin and PGF2α analogue used in animals to terminate pregnancy and induce corpus luteum dissolution.Formula:C22H29ClO6Purezza:99.81%Colore e forma:Clear Colorless To Light Yellowish LiquidPeso molecolare:424.92Sp-UTP-α-S
CAS:Sp-UTP-α-S serves as an activator of P2Y2 and P2Y4 receptors and is applicable in cancer research.Formula:C9H15N2O14P3SPeso molecolare:500.21Cannabigerovarin
CAS:Cannabigerovarin (CBGV) is a compound categorized as a phytocannabinoid.Formula:C19H28O2Peso molecolare:288.42Jimscaline
CAS:Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formula:C13H19NO3Peso molecolare:237.295IMP-1575
CAS:IMP-1575 is a highly effective inhibitor of hedgehog acyltransferase (HHAT), with an IC50 of 0.75 μM when inhibiting purified HHAT. IMP-1575 has potential applications in cancer research.Formula:C19H25N3OSPeso molecolare:343.49SSR 146977 hydrochloride
CAS:SSR 146977 hydrochloride is a potent, selective antagonist of the tachykinin NK 3 receptor, and it can be utilized in research on psychiatric disorders and airway inflammation [1].Formula:C35H43Cl3N4O2Peso molecolare:658.1Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:Formula:C27H29N5OColore e forma:SolidPeso molecolare:439.55MRGPRX1 agonist 3
Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.Formula:C14H11FN2OSColore e forma:SolidPeso molecolare:274.31Meluadrine
CAS:Meluadrine, a potent agonist of the β2 adrenergic receptor, is one of the metabolites of Tulobuterol [1].Formula:C12H18ClNO2Peso molecolare:243.73DNA crosslinker 6
CAS:DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.Formula:C19H21N7OColore e forma:SolidPeso molecolare:363.42GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formula:C30H28F4N6O5Peso molecolare:628.57Iralukast (CGP 45715A)
CAS:Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.Formula:C38H37F3O8SColore e forma:SolidPeso molecolare:710.7616(R)-Iloprost
CAS:Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Formula:C23H32N2O4Colore e forma:SolidPeso molecolare:400.511MDA7
CAS:<p>MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.</p>Formula:C22H25NO2Colore e forma:SolidPeso molecolare:335.439Anthrotainin
CAS:Anthrotainin is a tetracyclic compound that acts as an inhibitor of the binding of P substance (substance P), with an IC50 of 3 μM.Formula:C20H17NO9Colore e forma:SolidPeso molecolare:415.35Ro4368554
CAS:Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.Formula:C19H21N3O2SColore e forma:SolidPeso molecolare:355.454TM38837
CAS:<p>CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].</p>Formula:C27H20Cl2F3N7OColore e forma:SolidPeso molecolare:586.40H1R ligand-1
CAS:H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.Formula:C19H23NOColore e forma:SolidPeso molecolare:281.39212(S)-HEPE
CAS:12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.455-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Formula:C9H11ClINColore e forma:SolidPeso molecolare:295.548SGLT inhibitor-1
CAS:SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).Formula:C24H27FO8Purezza:98%Colore e forma:SolidPeso molecolare:462.46CP-199330
CAS:CP-199330: non-toxic alternative to Zafirlukast & Pranlukast, blocks cysteyl LT1 receptors.Formula:C28H24ClF3N2O6SColore e forma:SolidPeso molecolare:609.01PD 136450
CAS:PD-136,450: partial stomach secretory agonist, full pancreas agonist in rats; potential acid-reducing drug, adjuvant for gastrin-sensitive tumors.Formula:C35H40N4O6Purezza:98%Colore e forma:SolidPeso molecolare:612.72ChemR23-IN-3
ChemR23-IN-3 is a potent thiazole-based ChemR23 inhibitor with an IC 80 value of 12 nM.Formula:C31H33N5O5S2Colore e forma:SolidPeso molecolare:619.75Histamine H3 antagonist-1
CAS:<p>Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].</p>Formula:C24H28F3N3O2Colore e forma:SolidPeso molecolare:447.49EP4 receptor antagonist 7
CAS:EP4 receptor antagonist 7 (Compound 14) is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4, with an IC50 of 1.1 nM. This compound inhibits PGE2-induced β-arrestin recruitment in HEK293 cells with an IC50 of 0.9 nM. In RAW 264.7 macrophages, it reduces the expression of PGE2-induced IL-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C motif) ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase 1 (Arg1) mRNA. In the CT26 mouse colon cancer model, EP4 receptor antagonist 7, combined with an anti-PD-1 antibody, inhibits tumor growth and enhances CD8+ T cell infiltration into the tumor.Formula:C24H18F3N3O3Colore e forma:SolidPeso molecolare:453.413GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Formula:C31H31FN6O4Peso molecolare:570.61Gemilukast
CAS:Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.Formula:C36H37F2NO5Purezza:98.27% - 99.5%Colore e forma:SolidPeso molecolare:601.68Ref: TM-T11388
1mg115,00€5mg274,00€10mg472,00€25mg914,00€50mg1.415,00€100mg2.517,00€1mL*10mM (DMSO)363,00€LPA receptor antagonist-1
CAS:LPA receptor antagonist-1 (example 52) serves as an antagonist for the lysophosphatidic acid (LPA) receptor and is applicable in various types of studies [1].Formula:C30H26ClNO5SPeso molecolare:548.055-HT2A receptor agonist-7
CAS:5-HT2A receptor agonist-7 (517) functions as a modulator of the 5-HT2A receptor, with an EC50 value of less than 100 nM.Formula:C12H11F2N3Peso molecolare:235.233BI-113823
CAS:BI-113823 is an orally active and selective bradykinin B1 receptor antagonist. It alleviates mechanical hyperalgesia induced by complete Freund's adjuvant in rats. BI-113823 is applicable for research on chronic inflammatory pain.Formula:C26H44N4O5SColore e forma:SolidPeso molecolare:524.716Zaladenant
CAS:Zaladenant is an adenosine receptor antagonist with antitumor properties.Formula:C19H15F3N6OColore e forma:SolidPeso molecolare:400.357Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Formula:C20H23Cl2F2N3OPurezza:99.1%Colore e forma:SolidPeso molecolare:430.32D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Formula:C24H29N3O2Colore e forma:SolidPeso molecolare:391.50625B-NBOH hydrochloride
CAS:25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.Formula:C17H21BrClNO3Colore e forma:SolidPeso molecolare:402.711BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purezza:98.81%Colore e forma:SolidPeso molecolare:641.8Ref: TM-T10595
1mg137,00€2mg188,00€5mg329,00€10mg472,00€25mg753,00€50mg1.017,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)360,00€Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formula:C21H25Cl2F3N6OPurezza:98.99%Colore e forma:SolidPeso molecolare:505.36Ref: TM-T13329L
1mg99,00€5mg235,00€10mg376,00€25mg712,00€50mg1.064,00€100mg1.454,00€500mg2.822,00€1mL*10mM (DMSO)261,00€BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purezza:98.43% - 99.26%Colore e forma:SolidPeso molecolare:561.63Vofopitant
CAS:Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formula:C21H23F3N6OPurezza:97.86%Colore e forma:SolidPeso molecolare:432.44AZD5462
CAS:AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.Formula:C30H41FN2O6Purezza:98.32% - 99.63%Colore e forma:SolidPeso molecolare:544.65Treprostinil diethanolamine
CAS:Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,Formula:C27H45NO7Purezza:99.86%Colore e forma:SolidPeso molecolare:495.65SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purezza:98.99% - 99.96%Colore e forma:SolidPeso molecolare:557.08Ref: TM-T12841
1mg42,00€5mg88,00€10mg115,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)101,00€Dersimelagon
CAS:Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.Formula:C36H45F4N3O5Purezza:97.35% - 98.23%Colore e forma:SolidPeso molecolare:675.75LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Formula:C26H23Cl2N3O2Purezza:99.21%Colore e forma:SolidPeso molecolare:480.39AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formula:C32H38F2N2O5S2Purezza:98.1%Colore e forma:SolidPeso molecolare:632.78Ref: TM-T30260
1mg202,00€5mg459,00€10mg643,00€25mg938,00€50mg1.311,00€100mg1.786,00€1mL*10mM (DMSO)560,00€PF-07258669
CAS:PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.Formula:C25H27FN6O2Purezza:99.9%Colore e forma:SolidPeso molecolare:462.52SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formula:C26H32N2O4Purezza:99.22%Colore e forma:SolidPeso molecolare:436.54Ref: TM-T12846
1mg37,00€5mg80,00€10mg119,00€25mg210,00€50mg319,00€100mg442,00€200mg605,00€1mL*10mM (DMSO)89,00€Rolapitant hydrochloride
CAS:Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.Formula:C25H27ClF6N2O2Purezza:98.35% - 99.79%Colore e forma:SolidPeso molecolare:536.94Ref: TM-T3724
1mg153,00€5mg365,00€10mg520,00€25mg780,00€50mg1.054,00€100mg1.425,00€200mg1.882,00€1mL*10mM (DMSO)439,00€ML-290
CAS:ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.Formula:C24H21F3N2O5SColore e forma:SolidPeso molecolare:506.49CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Formula:C27H31N3O3S2Colore e forma:SolidPeso molecolare:509.68SHA 68
CAS:SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.Formula:C26H24FN3O3Purezza:98%Colore e forma:SolidPeso molecolare:445.49Protease-Activated Receptor-4
CAS:Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formula:C33H46N8O7Purezza:98%Colore e forma:SolidPeso molecolare:666.77Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Colore e forma:White SolidPeso molecolare:371.54BIBP3226 TFA
CAS:BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).Formula:C29H32F3N5O5Colore e forma:SolidPeso molecolare:587.59Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:339.84ML-00253764 hydrochloride
CAS:ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).Formula:C18H19BrClFN2OColore e forma:SolidPeso molecolare:413.71SR 146131
CAS:SR 146131 is a potent and selective agonist of the nonpeptide receptor.Formula:C32H36ClN3O5SPurezza:98%Colore e forma:SolidPeso molecolare:610.16SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formula:C18H22Cl3N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:482.817-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formula:C14H15NO2Colore e forma:SolidPeso molecolare:229.27HOKU-81
CAS:HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.Formula:C12H18ClNO2Colore e forma:SolidPeso molecolare:243.73Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Formula:C24H29NaO5Colore e forma:SolidPeso molecolare:420.481JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Formula:C30H32N6O2Colore e forma:SolidPeso molecolare:508.61Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purezza:98%Colore e forma:LiquidRef: TM-T81538
Prodotto fuori produzione1-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Formula:C21H41O7PColore e forma:SolidPeso molecolare:436.52N-methyl-2-AI (hydrochloride)
CAS:N-methyl-2-AI (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T66396 and the CAS number is 10408-85-2.Formula:C10H14ClNColore e forma:SolidPeso molecolare:183.68BRL 15572
CAS:BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formula:C25H27ClN2OColore e forma:SolidPeso molecolare:406.95Desmethyl cariprazine
CAS:Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formula:C20H30Cl2N4OPurezza:98%Colore e forma:SolidPeso molecolare:413.384-Hydroxyatomoxetine
CAS:4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.Formula:C17H21NO2Purezza:98%Colore e forma:SolidPeso molecolare:271.35Picumeterol
CAS:Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.Formula:C21H29Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:426.386-Chloro-5-(2-chloroethyl)indolin-2-one
CAS:6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.Formula:C10H9Cl2NOColore e forma:SolidPeso molecolare:230.091-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol
CAS:1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol is a useful organic compound for research related to life sciences. The catalog number is T65156 and the CAS number is 24155-42-8.Formula:C11H10Cl2N2OColore e forma:SolidPeso molecolare:257.11(R)-(-)-α-Methylhistamine dihydrochloride
CAS:R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formula:C6H13Cl2N3Colore e forma:SolidPeso molecolare:198.09SKF 89748
CAS:SKF 89748 is an agonists of alpha 1-adrenoceptor.Formula:C12H17NOSPurezza:98%Colore e forma:SolidPeso molecolare:223.33Vornorexant
CAS:Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Formula:C23H22FN7O2Colore e forma:SolidPeso molecolare:447.474Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Colore e forma:Odour LiquidGoserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Purezza:99.77%Colore e forma:Odour Solid(Rac)-Zevaquenabant
CAS:(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Formula:C25H21ClF3N5O2SColore e forma:SolidPeso molecolare:547.98Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Formula:C16H25N3O·xClHPurezza:99.25%Colore e forma:SoildTAK-683
CAS:TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.Formula:C64H83N17O13Purezza:98%Colore e forma:SolidPeso molecolare:1298.453-Hydroxybenzylamine
CAS:3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.Formula:C7H9NOColore e forma:SolidPeso molecolare:123.1554-Hydroxypropranolol hydrochloride
CAS:4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).Formula:C16H22ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:311.8TAK-448
CAS:TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.Formula:C58H80N16O14Purezza:98%Colore e forma:SolidPeso molecolare:1225.36Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formula:C22H21FN2OColore e forma:SolidPeso molecolare:348.421Amelubant
CAS:Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.Formula:C33H34N2O5Purezza:98%Colore e forma:SolidPeso molecolare:538.63dapitant
CAS:Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.Formula:C37H39NO4Colore e forma:SolidPeso molecolare:561.71BX471 hydrochloride
CAS:BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Formula:C21H25Cl2FN4O3Purezza:98%Colore e forma:SolidPeso molecolare:471.35GSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Colore e forma:Odour LiquidCRTh2 antagonist 3
CAS:CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.Formula:C19H20N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:356.44Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Formula:C24H25FO5SPurezza:98%Colore e forma:SolidPeso molecolare:448.54Ref: TM-T10669
Prodotto fuori produzioneRU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Colore e forma:SolidPeso molecolare:346.382-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H15ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:226.7Ref: TM-T10075L2
Prodotto fuori produzionePamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Formula:C23H16O6Purezza:99.99%Colore e forma:Fine Yellow PowderPeso molecolare:388.37Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formula:C11H12F3NOPurezza:98%Colore e forma:SolidPeso molecolare:231.21GR 218,231
CAS:GR 218,231 is a selective antagonist of D3 dopamine receptor.Formula:C24H33NO3SPurezza:98%Colore e forma:SolidPeso molecolare:415.59Ref: TM-T27431
Prodotto fuori produzioneNeurokinin antagonist 1
CAS:Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Formula:C38H40N4O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:600.75Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formula:C6H12Br2N4SPurezza:98%Colore e forma:SolidPeso molecolare:332.06MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Formula:C38H40N4O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:600.75SB251023
CAS:SB251023 is an agonist of β3-adrenoceptor.Formula:C28H34NO6PColore e forma:SolidPeso molecolare:511.55S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purezza:98%Colore e forma:SolidPeso molecolare:445.47AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purezza:99.58%Colore e forma:SolidPeso molecolare:436.632-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Formula:C8H8N2O3SColore e forma:LiquidPeso molecolare:212.23Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:470.73Ref: TM-T27176
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