Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.016 prodotti)
- Recettore dell'adenosina(211 prodotti)
- Recettore adrenergico(3.154 prodotti)
- Recettore della bombesina(34 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(159 prodotti)
- CaSR(30 prodotti)
- Recettore dei cannabinoidi(220 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(444 prodotti)
- Recettore dell'endotelina(85 prodotti)
- Recettore GNRH(86 prodotti)
- GPCR19(37 prodotti)
- GRK(34 prodotti)
- GTPase(23 prodotti)
- Recettore del glucagone(197 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(389 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(330 prodotti)
- PAFR(11 prodotti)
- PKA(57 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(48 prodotti)
Mostrare 19 più sottocategorie
Trovati 5836 prodotti per "Proteina G/GPCR".
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KB-5492 FA
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8Formula:C24H32N2O8Purezza:98.12%Colore e forma:SolidPeso molecolare:476.52CAY10597
CAS:PGD2 effects via DP1/CRTH2/DP2 receptors; CAY10597 blocks CRTH2/DP2 (Ki=37nM), R enantiomer stronger (Ki=23-22nM), inhibits eosinophil migration (IC50=40nM).Formula:C20H14ClFN2O5Colore e forma:SolidPeso molecolare:416.79Vazegepant
CAS:Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.Formula:C36H46N8O3Purezza:98.61% - 99.98%Colore e forma:White SolidPeso molecolare:638.80Ref: TM-T38734
1mg90,00€5mg215,00€1mL*10mM (DMSO)289,00€10mg318,00€25mg537,00€50mg767,00€100mg1.054,00€Thiothixene
CAS:Thiothixene has a wide range of applications in life science related research.Formula:C23H29N3O2S2Colore e forma:SolidPeso molecolare:443.62Lu AA33810
CAS:Lu AA33810 is a selective neuropeptide Y5 (NPY5) receptor antagonist with an oral activity and BBB permeability, anti-anxiety and antidepressant-like effects.Formula:C19H25N3O2S3Purezza:97.92% - 99.61%Colore e forma:SolidPeso molecolare:423.62BIBP3226
CAS:BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.Formula:C27H31N5O3Colore e forma:SolidPeso molecolare:473.57tetranor-PGJM
CAS:Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.Formula:C16H22O6Colore e forma:SolidPeso molecolare:310.346Adrenotensin (human)
CAS:Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Formula:C143H224N42O43Colore e forma:SolidPeso molecolare:3219.56Cholecystokinin Octapeptide, desulfated
CAS:Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) is an octapeptide composed of 8 amino acids from cholecystokinin-8.Formula:C49H62N10O13S2Purezza:97.12%Colore e forma:White SolidPeso molecolare:1063.21Orforglipron hemicalcium hydrate
CAS:Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].Formula:C48H48F2N10O5Ca·H2OColore e forma:SolidPeso molecolare:921.02Prosaptide TX14(A)
CAS:GPR37L1/GPR37 agonist with EC50 of 5/7 nM, activates G proteins, enhances ERK, myelin synthesis, neuro/glioprotection.Formula:C69H110N16O26Purezza:98%Colore e forma:SolidPeso molecolare:1579.72TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.Formula:C37H59N2NaO9SColore e forma:SolidPeso molecolare:730.93Endothelin 1 (swine, human), Alexa Fluor 488-labeled
Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.Colore e forma:SolidPeso molecolare:2848.4Desmethyl Mirtazapine (hydrochloride)
CAS:Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.Formula:C16H18ClN3Colore e forma:SolidPeso molecolare:287.79Urocortin III (human)
CAS:Urocortin III, a human peptide, binds CRF-R2, affecting insulin via somatostatin feedback with K i values 13.5-100+ nM.Formula:C185H307N53O50S2Colore e forma:SolidPeso molecolare:4137.93APJ receptor agonist 10
CAS:APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.Formula:C26H36N7O6SColore e forma:SolidPeso molecolare:574.67O-2172
CAS:O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).Formula:C14H16Cl2O2Colore e forma:SolidPeso molecolare:287.18Amylin (8-37), human
CAS:Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.Formula:C138H216N42O45Colore e forma:SolidPeso molecolare:3183.495Angiopeptin TFA
CAS:Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.Formula:C58H73F6N11O14S2Colore e forma:SolidPeso molecolare:1326.39Amylin (8-37), rat
CAS:Amylin (8-37), rat, an analog of IAPP, blocks insulin's effects on muscle glucose uptake and glycogen storage.Formula:C140H227N43O43Purezza:98%Colore e forma:SolidPeso molecolare:3200.61Halometasone
CAS:Halometasone: synthetic corticosteroid for psoriasis and eczema treatment.Formula:C22H27ClF2O5Colore e forma:SolidPeso molecolare:444.9Apigenin 6,8-di-C-α-L-arabinopyranoside
CAS:Apigenin 6,8-di-C-alpha-L-arabinopyranoside is a useful organic compound for research related to life sciences.Formula:C25H26O13Colore e forma:SolidPeso molecolare:534.47SAE-14
CAS:GPR183, a chemotactic receptor aiding B cell maturation, binds 7α,25-OHC; studied in IBD research.Formula:C19H19F3N2O2Purezza:99.85%Colore e forma:SolidPeso molecolare:364.36Dapiglutide
CAS:Dapiglutide (ZP7570) is a long-acting GLP-1R & GLP-2R dual agonist for SBS research.Colore e forma:SolidA71378
CAS:A71378 is a high potency, selectivity CCK-A receptors agonist.Formula:C48H62N8O13SPurezza:98%Colore e forma:SolidPeso molecolare:991.12Relaxin H3 (human)
CAS:Relaxin H3 (human) is a relaxin peptide that exhibits antifibrotic effects through activation of RXFP1 [1].Colore e forma:SolidCalcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.Formula:C165H268F3N51O52S2Colore e forma:SolidPeso molecolare:3919.33a-Helical Corticotropin Releasing Factor (9-41)
CAS:α-Helical CRF (9-41) is a CRF antagonist that lowers in vivo plasma GH levels.Formula:C166H273N45O54S2Colore e forma:SolidPeso molecolare:3827.34(D-Phe7)-α-MSH
CAS:(D-Phe7)-α-MSH is an α-MSH analogue [1] .Formula:C77H109N21O19SColore e forma:SolidPeso molecolare:1664.88BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.Formula:C59H77F3N14O13Colore e forma:SolidPeso molecolare:1247.32ELA-11(human) TFA
ELA-11(human) TFA: apelin receptor agonist, K i =14 nM, inhibits cAMP, stimulates β-arrestin, from ELA-32 fragment.Formula:C60H91F3N16O15S2Colore e forma:SolidPeso molecolare:1397.58NF157
CAS:NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.Formula:C49H28F2N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1437.1Taspoglutide
CAS:Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetesFormula:C152H232N40O45Purezza:98%Colore e forma:SolidPeso molecolare:3339.763Adenosine receptor antagonist 1
CAS:A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.Formula:C22H15ClFN7OColore e forma:SolidPeso molecolare:447.86[Tyr3]Octreotate
CAS:[Tyr3]Octreotate is a long peptide compound containing 8 amino acids and is a functional DOTA chelating agent with covalent bonds.Formula:C49H64N10O12S2Purezza:99.77%Colore e forma:SolidPeso molecolare:1049.22Picumeterol FA
picumeterol FA is a potent and selective β2-adrenergic receptor agonist.Formula:C22H31Cl2N3O4Purezza:99.97%Colore e forma:SoildPeso molecolare:472.4Jmv 179
CAS:Jmv 179 is an antagonist of the cholecystokinin receptor.Formula:C51H67N7O15SColore e forma:SolidPeso molecolare:1050.19GI-560192
CAS:GI-560192 (RL-0070933), a potent smo modulator, EC50: 0.02µM; affects smoothened in cilia via hedgehog signaling.Formula:C20H16N2O2Purezza:99.53%Colore e forma:SoildPeso molecolare:316.35Ref: TM-T64351
1mg85,00€5mg170,00€1mL*10mM (DMSO)170,00€10mg250,00€25mg371,00€50mg522,00€100mg712,00€200mg954,00€AA 497 HCl
CAS:AA 497, a beta-2 agonist, suppresses Ca spikes.Formula:C14H22ClNO3Colore e forma:SolidPeso molecolare:287.78[Ala17]-MCH acetate
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled).Formula:C99H159N29O28S4Purezza:98.92%Colore e forma:SolidPeso molecolare:2331.766α-Prostaglandin I1
CAS:6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.Formula:C20H34O5Colore e forma:SolidPeso molecolare:354.487Zicronapine fumarate
CAS:Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.Formula:C26H31ClN2O4Colore e forma:SolidPeso molecolare:470.9926Rfa, Hypothalamic Peptide, human
CAS:26RFa, a human neuropeptide, stimulates appetite and possibly regulates feeding and the gonadotropic axis, with ≈80% identity across human, rat, and frog.Formula:C127H195N37O37Purezza:98%Colore e forma:SolidPeso molecolare:2832.13A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.Formula:C23H25IN4Colore e forma:SolidPeso molecolare:484.38Substance P, Free Acid
CAS:Substance P, Free Acid is a synthetic analog of native Substance P, however, it lacks the biological activity exhibited by Substance P.Formula:C63H97N17O14SPurezza:98%Colore e forma:SolidPeso molecolare:1348.61BMS-753426
CAS:BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .Formula:C25H33F3N6O2Colore e forma:SolidPeso molecolare:506.574SFNGGP-NH2
CAS:SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor.Formula:C25H36N8O8Colore e forma:SolidPeso molecolare:576.6ORG 2766
CAS:ORG 2766 is an ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog and neurotrophic peptide.Formula:C40H55N9O11SColore e forma:SolidPeso molecolare:869.99Mitemcinal fumarate
CAS:Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.Formula:C84H142N2O28Colore e forma:SolidPeso molecolare:1628.02Tetrahydro-β-carboline
CAS:Tetrahydro-β-carboline ,with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tetrahydro-β-carboline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H12N2Purezza:96.31%Colore e forma:Tan SolidPeso molecolare:172.2264
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