Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.017 prodotti)
- Recettore dell'adenosina(211 prodotti)
- Recettore adrenergico(3.060 prodotti)
- Recettore della bombesina(34 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(159 prodotti)
- CaSR(31 prodotti)
- Recettore dei cannabinoidi(220 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(444 prodotti)
- Recettore dell'endotelina(85 prodotti)
- Recettore GNRH(86 prodotti)
- GPCR19(37 prodotti)
- GRK(34 prodotti)
- GTPase(23 prodotti)
- Recettore del glucagone(197 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(389 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(330 prodotti)
- PAFR(11 prodotti)
- PKA(58 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(48 prodotti)
Mostrare 19 più sottocategorie
Trovati 5839 prodotti per "Proteina G/GPCR".
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Prochlorperazine Maleate
CAS:Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO.Formula:C28H32ClN3O8SPurezza:99.78%Colore e forma:Off-White PowderPeso molecolare:606.09Chlorprothixene hydrochloride
CAS:Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.Formula:C18H18ClNS·HClPurezza:99.76% - 99.97%Colore e forma:White SolidPeso molecolare:352.32CP-809101 hydrochloride
CAS:CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).Formula:C15H18Cl2N4OPurezza:99.5%Colore e forma:Yellow SolidPeso molecolare:341.24Nylidrin hydrochloride
CAS:Nylidrin HCl inhibits IgG1-induced histamine release in guinea pigs and IgE-induced release in rat mast cells & human basophils.Formula:C19H26ClNO2Purezza:99.35%Colore e forma:White SolidPeso molecolare:335.87Cyproheptadine hydrochloride sesquihydrate
CAS:Cyproheptadine hydrochloride sesquihydrate (Peritol), an antihistamine, is an antagonist of serotonin and histamine2.Formula:C21H24ClNOPurezza:99.77% - 99.99%Colore e forma:White SolidPeso molecolare:341.88Prucalopride
CAS:Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.Formula:C18H26ClN3O3Purezza:99.99% - >99.99%Colore e forma:White SolidPeso molecolare:367.87Filorexant
CAS:Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).Formula:C24H25FN4O2Purezza:98.88%Colore e forma:SolidPeso molecolare:420.48Alverine citrate
CAS:Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.Formula:C26H35NO7Purezza:98.53% - 99.43%Colore e forma:SolidPeso molecolare:473.57Ondansetron hydrochloride dihydrate
CAS:Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.Formula:C18H19N3O·HCl·2H2OPurezza:99.92%Colore e forma:SolidPeso molecolare:365.86Metaproterenol hemisulfate
CAS:Metaproterenol hemisulfate (Orciprenaline sulfate) is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.Formula:C11H17NO3·5H2O4SPurezza:98.53% - 99.74%Colore e forma:White SolidPeso molecolare:260.3Silodosin
CAS:Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.Formula:C25H32F3N3O4Purezza:99.28% - 99.76%Colore e forma:White SolidPeso molecolare:495.53Ref: TM-T1504
5mg34,00€1mL*10mM (DMSO)35,00€10mg50,00€25mg73,00€50mg92,00€100mg99,00€200mg126,00€1500mg267,00€Lafutidine
CAS:Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.Formula:C22H29N3O4SPurezza:99.96%Colore e forma:Yellowish White Crystalline PowderPeso molecolare:431.55KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Formula:C26H40N4O8Purezza:98.46%Colore e forma:SolidPeso molecolare:536.62Ref: TM-T15656
1mg109,00€2mg158,00€5mg260,00€1mL*10mM (DMSO)305,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€Roxatidine Acetate hydrochloride
CAS:Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. Roxatidine inhibits gastric acid secretion.Formula:C19H29ClN2O4Purezza:99.49%Colore e forma:SolidPeso molecolare:384.9Clonidine hydrochloride
CAS:Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.Formula:C9H10Cl3N3Purezza:99.16% - 99.86%Colore e forma:SolidPeso molecolare:266.55JNJ-18038683
CAS:JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.Formula:C26H28ClN3O7Purezza:97.29%Colore e forma:SolidPeso molecolare:529.97Ref: TM-T11720
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg86,00€25mg161,00€50mg245,00€100mg363,00€200mg515,00€Talastine
CAS:Talastine is an antihistamine compound that can induce an allergic rash.Formula:C19H21N3OPurezza:99.44% - 99.84%Colore e forma:SolidPeso molecolare:307.399-Cyclopentyladenine
CAS:9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signalingFormula:C10H13N5Purezza:99.98%Colore e forma:White SolidPeso molecolare:203.24Granisetron hydrochloride
CAS:Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapyFormula:C18H25ClN4OPurezza:99.88% - 99.93%Colore e forma:White SolidPeso molecolare:348.87Venlafaxine hydrochloride
CAS:Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.Formula:C17H28ClNO2Purezza:97.32% - 99.86%Colore e forma:SolidPeso molecolare:313.86MK-0249 FA
MK-0249 FA is an H3 inverse agonist that can be used to study attention-deficit, hyperactivity disorder and cognitive disorders in adults.Formula:C24H26F3N3O4Purezza:99.98%Colore e forma:SolidPeso molecolare:477.48Upidosin
CAS:Upidosin (SB-216469), a uroselective α1 blocker: Ki α1a=0.34 nM, α1b=3.9 nM, α1d=1.5 nM, α2=33.3 nM.Formula:C31H33N3O4Purezza:99.66%Colore e forma:SolidPeso molecolare:511.61Zolmitriptan
CAS:Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.Formula:C16H21N3O2Purezza:99.69% - 99.91%Colore e forma:White SolidPeso molecolare:287.36Quetiapine
CAS:Quetiapine treats schizophrenia and bipolar I, targeting serotonin, dopamine, and adrenoreceptor subtypes, plus H1 histamine receptor.Formula:C21H25N3O2SPurezza:99.14% - 99.96%Colore e forma:Transparent SolidPeso molecolare:383.51Ziprasidone hydrochloride
CAS:Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychoticFormula:C21H22CL2N4OSPurezza:97.97% - 99.82%Colore e forma:White SolidPeso molecolare:449.4Promazine hydrochloride
CAS:Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.Formula:C17H21ClN2SPurezza:99.90%Colore e forma:SolidPeso molecolare:320.88Astressin acetate
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the clonedFormula:C163H273N49O44Purezza:98.09%Colore e forma:SolidPeso molecolare:3623.21Salmeterol
CAS:Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.Formula:C25H37NO4Purezza:99.2% - 99.9%Colore e forma:SolidPeso molecolare:415.57Levosulpiride
CAS:Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.Formula:C15H23N3O4SPurezza:98.20% - 99.88%Colore e forma:White SolidPeso molecolare:341.43Rimonabant
CAS:Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.Formula:C22H21Cl3N4OPurezza:98% - 99.91%Colore e forma:White SolidPeso molecolare:463.79Olinciguat
CAS:Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.Formula:C21H16F5N7O3Purezza:99.33% - 99.71%Colore e forma:SolidPeso molecolare:509.39Ref: TM-T16383
1mg170,00€5mg430,00€1mL*10mM (DMSO)475,00€10mg620,00€25mg973,00€50mg1.333,00€100mg1.765,00€Alfuzosin hydrochloride
CAS:Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).Formula:C19H27N5O4·HClPurezza:99.78%Colore e forma:White To Off-White SolidPeso molecolare:425.91Fluparoxan hydrochloride
CAS:Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmentalFormula:C10H11ClFNO2Purezza:99.98%Colore e forma:SolidPeso molecolare:231.65Antazoline hydrochloride
CAS:Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenousFormula:C17H19N3·HClPurezza:98% - 99.53%Colore e forma:White SolidPeso molecolare:301.82Urocortin (rat) acetate
Urocortin (rat) acetate: CRF receptor agonist; Ki=13nM (hCRF1), 1.5nM (rCRF2α), 0.97nM (mCRF2β); neuropeptide.Purezza:97.76%Colore e forma:White SolidYNT-185
CAS:YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74Serazapine
CAS:Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.Formula:C22H23N3O2Purezza:99.29% - 99.97%Colore e forma:White SolidPeso molecolare:361.44Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Formula:C28H32N2O7Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:508.56Bambuterol hydrochloride
CAS:Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.Formula:C18H30ClN3O5Purezza:99.53% - 99.61%Colore e forma:SolidPeso molecolare:403.91ESI-05
CAS:ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.Formula:C16H18O2SPurezza:97.22%Colore e forma:SolidPeso molecolare:274.38Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purezza:99.43% - 99.62%Colore e forma:White SolidPeso molecolare:448.39LCKLSL hydrochloride
LCKLSL hydrochloride is an AnxA2 inhibitor with potential anti-angiogenic activity and inhibits the development of EAE.Formula:C30H58ClN7O8SPurezza:98.02% - 99.31%Colore e forma:White SolidPeso molecolare:712.34(3aR,9aR)-Fluparoxan
CAS:(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmentalFormula:C10H10FNO2Purezza:97.82%Colore e forma:SolidPeso molecolare:195.19Ethamsylate
CAS:Ethamsylate (Dicynene) 通常用作止血药，增加毛细血管内皮阻力和血小板粘附，抑制前列腺素的生物合成和作用。Formula:C10H17NO5SPurezza:98.55%Colore e forma:SolidPeso molecolare:263.31AH 6809
CAS:AH 6809 blocks EP1, EP2, EP3, DP receptors (Ki: 1217-1597 nM human, 350 nM mouse EP2).Formula:C17H14O5Purezza:97.59%Colore e forma:SolidPeso molecolare:298.29Ref: TM-T14148
1mg34,00€5mg63,00€1mL*10mM (DMSO)67,00€10mg92,00€25mg165,00€50mg250,00€100mg401,00€200mg580,00€Fluvoxamine maleate
CAS:Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxietyFormula:C19H25F3N2O6Purezza:99.92% - 99.94%Colore e forma:White SolidPeso molecolare:434.41Ref: TM-T1077
1mL*10mM (DMSO)35,00€10mg49,00€25mg65,00€50mg80,00€100mg109,00€200mg161,00€500mg263,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65Fexofenadine hydrochloride
CAS:Fexofenadine Hydrochloride is a carboxylated metabolic derivative of terfenadine and long-lasting selective histamine H1 receptor antagonist, withFormula:C32H40ClNO4Purezza:>99.99%Colore e forma:White SolidPeso molecolare:538.122-Bromo-6-methoxynaphthalene
CAS:2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.Formula:C11H9BrOPurezza:98.51%Colore e forma:SolidPeso molecolare:237.09Anatibant 2HCl
CAS:Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury.Formula:C34H36Cl2N6O5S·2ClHPurezza:99.17% - 99.2%Colore e forma:SolidPeso molecolare:784.58
