Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(942 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.949 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(149 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(410 prodotti)
- Recettore dell'endotelina(75 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(32 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(166 prodotti)
- Proteina Hedgehog/Smoothened(45 prodotti)
- Recettore dell'istamina(359 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(298 prodotti)
- PAFR(11 prodotti)
- PKA(49 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5378 prodotti di "Proteina G/GPCR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
β2AR/M-receptor agonist-1
CAS:<p>β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and</p>Formula:C43H56BrN3O7Colore e forma:SolidPeso molecolare:806.82[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:<p>Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.</p>Formula:C79H109N19O12Purezza:98%Colore e forma:SolidPeso molecolare:1516.85PD 144418 oxalate
CAS:<p>PD 144418 oxalate: σ1 receptor ligand, Ki=0.08 nM; 1377 nM for σ2, minimal affinity elsewhere; potential antipsychotic.</p>Formula:C20H24N2O5Purezza:98.76%Colore e forma:SolidPeso molecolare:372.424-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine
CAS:<p>4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric</p>Formula:C27H28ClFN2OSPurezza:99.02%Colore e forma:SoildPeso molecolare:483.04Neurokinin B acetate(86933-75-7 free base)
<p>Neurokinin B acetate, a tachykinin, interacts with NK1R, NK2R, & NK3R receptors to exert biological effects.</p>Formula:C57H83N13O16S2Purezza:98.53%Colore e forma:SolidPeso molecolare:1270.48Pentagastrin meglumine
CAS:<p>Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.</p>Formula:C44H66N8O14SColore e forma:SolidPeso molecolare:963.11Benzoquinamide hydrochloride
CAS:<p>Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic</p>Formula:C22H33ClN2O5Purezza:97.13% - 99.56%Colore e forma:SolidPeso molecolare:440.96Asenapine citrate
CAS:<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formula:C23H24ClNO8Colore e forma:SolidPeso molecolare:477.89Pasireotide
CAS:Pasireotide (SOM 230) is a cyclohexapeptide, mimicking somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).Formula:C58H66N10O9Purezza:98%Colore e forma:SolidPeso molecolare:1047.21Colulintide
CAS:<p>Colulintide is an analog of amylin, utilized in obesity research.</p>Colore e forma:SolidNeurokinin Receptor (393-407), rat
CAS:<p>Rat NK1R fragment (393-407) binds SP, enabling endocytosis and plasma membrane recycling; key in neurogenic inflammation research.</p>Formula:C72H113N17O26S2Colore e forma:SolidPeso molecolare:1696.9Cortistatin-8
CAS:<p>ghrelin receptor antagonist</p>Formula:C47H68N12O9S2Purezza:98%Colore e forma:SolidPeso molecolare:1009.255-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32Levitide
CAS:<p>Levitide is a neurohormone-like peptide which is from the skin of Xenopus laevis.</p>Formula:C66H119N21O19SPurezza:98%Colore e forma:SolidPeso molecolare:1542.85Cortistatin 14, human, rat
CAS:<p>Cortistatin 14: a neuropeptide similar to somatostatin; induces sleep, depresses neuronal activity; found in cortex, hippocampus.</p>Formula:C81H113N19O19S2Purezza:98%Colore e forma:SolidPeso molecolare:1721.01BAY-747
CAS:<p>BAY-747: oral, brain-penetrant sGC stimulator; improves rat memory, cognition, lowers blood pressure, aids Duchenne muscular dystrophy.</p>Formula:C22H26F2N4O2Colore e forma:SolidPeso molecolare:416.46PACAP (1-27), human, ovine, rat
CAS:PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.Formula:C142H224N40O39SPurezza:98%Colore e forma:SolidPeso molecolare:3147.66Vapitadine
CAS:<p>Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.</p>Formula:C17H20N4OPurezza:99.77% - 99.86%Colore e forma:SoildPeso molecolare:296.37Glucagon (19-29), human
CAS:Glucagon, a 29-amino-acid hormone, is produced by alpha cells in the pancreas' islets of Langerhans.Formula:C61H89N15O18SPurezza:98%Colore e forma:SolidPeso molecolare:1352.53Preclamol hydrochloride
CAS:<p>Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.</p>Formula:C14H22ClNOColore e forma:SolidPeso molecolare:255.78Δ8-THC-C8
CAS:<p>Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.</p>Formula:C24H36O2Colore e forma:SolidPeso molecolare:356.54Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Colore e forma:Odour SolidRVD-Hpα
CAS:<p>N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>Formula:C65H105N19O17Purezza:98%Colore e forma:SolidPeso molecolare:1424.66PSB 0777 ammonium salt
CAS:<p>adenosine A2A receptor full agonist</p>Formula:C18H24N6O7S2Purezza:98%Colore e forma:SolidPeso molecolare:500.55[His1,Nle27] GHRF (1-32), amide, human
CAS:<p>[His1,Nle27] GHRF (1-32), amide, human is a potent GHRH analog with high GHRHR affinity.</p>Formula:C159H265N51O46Colore e forma:SolidPeso molecolare:3627.12Denrakibart
<p>Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.</p>Colore e forma:Odour LiquidRS 18286
CAS:<p>RS 18286 is a LHRH antagonist.</p>Formula:C74H101Cl2N17O14Colore e forma:SolidPeso molecolare:1523.6Xanthine amine congener trihydrochloride
CAS:<p>Xanthine amine congener trihydrochloride: potent adenosine antagonist, reverses effects of N6-cyclohexyladenosine on urine, sodium excretion, heart rate.</p>Formula:C21H29ClN6O4Purezza:98.81%Colore e forma:SolidPeso molecolare:464.95SYD5115
<p>SYD5115 is an orally active TSH-R antagonist.</p>Formula:C22H32F2N4O3Peso molecolare:438.24425TLX agonist 2
<p>TLX agonist 2 (compound 31) is a TLX agonist with an EC50 of 0.1 μM and a Kd of 0.16 μM. This compound enhances transcriptional activity by binding to TLX, thereby boosting the expression of TLX target genes. TLX agonist 2 is utilized in research on neurodegenerative diseases.</p>Colore e forma:Odour Solidpalm11-PrRP31
<p>Palm11-PrRP31 is a lipid-modified analog of the endogenous appetite-suppressing neuropeptide (PrRP). It functions as a potent dual agonist for GPR10 (EC50 = 39 pM) and NPFF-R2. By mimicking the natural activity of PrRP, palm11-PrRP31 binds to these receptors to reduce food intake. It has potential applications as an anti-obesity agent and is useful in studying neuropeptide and receptor interactions.</p>Formula:C181H289N55O46SPeso molecolare:4001.16865ALD1613
<p>ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.</p>Colore e forma:Odour Liquid11β-Prostaglandin E2
CAS:<p>11β-PGE2 is the C-11 epimer of PGE2.</p>Formula:C20H32O5Colore e forma:SolidPeso molecolare:352.47PHM-27 (human)
CAS:<p>Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.</p>Formula:C135H214N34O40SPurezza:98%Colore e forma:SolidPeso molecolare:2985.44MRS 2365
CAS:<p>Highly potent, selective P2Y1 receptor agonist</p>Formula:C13H19N5O9P2SPurezza:98%Colore e forma:SolidPeso molecolare:483.33SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formula:C34H45N3OPurezza:99.83%Peso molecolare:511.74ACT-1016-0707
CAS:<p>ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis models</p>Formula:C19H23ClN4O4SPurezza:99.905%Colore e forma:SolidPeso molecolare:438.936-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.31Dopamine D2 receptor agonist-2
CAS:<p>Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.</p>Formula:C25H31Cl2N5OSPurezza:98.93%Colore e forma:SoildPeso molecolare:520.52LAS190792
CAS:<p>LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.</p>Formula:C39H43ClN4O9S2Colore e forma:SolidPeso molecolare:811.36Luseogliflozin hydrate
CAS:<p>Luseogliflozin hydrate: SGLT2 inhibitor, IC50 2.26 nM, oral, for type 2 diabetes research.</p>Formula:C23H32O7SColore e forma:SolidPeso molecolare:452.56Kisspeptin 234
CAS:<p>Kisspeptin receptor antagonist; blocks kisspeptin-10 effects on IP (IC50 = 7 nM) and GnRH release.</p>Formula:C63H78N18O13Purezza:98%Colore e forma:SolidPeso molecolare:1295.42Hemokinin 1, human TFA
<p>Hemokinin-1 is a human TFA and selective NK1 agonist; also activates NK2 & NK3 and induces opioid-independent analgesia.</p>Formula:C56H85F3N14O16SColore e forma:SolidPeso molecolare:1299.42CAY10509
CAS:<p>CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.</p>Formula:C23H35FO5SColore e forma:SolidPeso molecolare:442.58Atrial natriuretic factor (1-28) (rat) TFA
<p>ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.</p>Formula:C130H206N45F3O41S2Purezza:98%Colore e forma:SolidPeso molecolare:3176.43PF-03382792
CAS:<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Formula:C23H32FN3O4Purezza:99.64%Colore e forma:SolidPeso molecolare:433.52(R)-CJ 11974
CAS:<p>(R)-CJ 11974: non-peptide NK1 receptor antagonist, may relieve pain and prevent chemo-induced vomiting.</p>Formula:C31H38N2OPurezza:97.15%Colore e forma:SoildPeso molecolare:454.65ELA-11(human)
CAS:<p>Apelin receptor agonist with high affinity (Ki = 14 nM). Blocks cAMP production and promotes β-arrestin activation; derived from ELA-32.</p>Formula:C58H90N16O13S2Purezza:98%Colore e forma:SolidPeso molecolare:1283.574-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formula:C12H18BrNO2Colore e forma:SolidPeso molecolare:288.1825E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Formula:C20H28ClNO3Colore e forma:SolidPeso molecolare:365.89
![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1931.webp&w=3840&q=75)
![4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-me…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60126.webp&w=3840&q=75)
