Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BA 1 TFA
<p>BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.</p>Formula:C59H77F3N14O13Colore e forma:SolidPeso molecolare:1247.32Dapiglutide
CAS:<p>Dapiglutide (ZP7570) is a long-acting GLP-1R & GLP-2R dual agonist for SBS research.</p>Colore e forma:SolidRelaxin H3 (human)
CAS:<p>Relaxin H3 (human) is a relaxin peptide that exhibits antifibrotic effects through activation of RXFP1 [1].</p>Colore e forma:Solida-Helical Corticotropin Releasing Factor (9-41)
CAS:<p>α-Helical CRF (9-41) is a CRF antagonist that lowers in vivo plasma GH levels.</p>Formula:C166H273N45O54S2Colore e forma:SolidPeso molecolare:3827.34Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
CAS:<p>Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potent</p>Formula:C45H63N15O11S2Colore e forma:SolidPeso molecolare:1054.21MGV354
<p>MGV354 is a soluble activator of guanylate cyclase(sGC) with EC 50 s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively [1] [2].</p>Formula:C35H37N5O3Purezza:98%Colore e forma:SolidPeso molecolare:575.7Neuropeptide S(Mouse) TFA
<p>Neuropeptide S(Mouse) TFA: Endogenous NPSR agonist, EC50 3 nM, boosts Ca2+, activity, wakefulness, and lowers mouse anxiety.</p>Formula:C92H157F3N34O29Colore e forma:SolidPeso molecolare:2296.49Calcitonin Gene Related Peptide (CGRP) II, rat TFA
<p>Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.</p>Formula:C165H268F3N51O52S2Colore e forma:SolidPeso molecolare:3919.33Cortistatin 29
<p>Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.</p>Formula:C161H242N46O41S2Colore e forma:SolidPeso molecolare:3539.77a-Helical Corticotropin Releasing Factor (12-41)
CAS:<p>α-Helical CRF (12-41), a 30-aa analog, curbs CRF's ACTH-stimulating effect.</p>Formula:C152H251N43O47S2Colore e forma:SolidPeso molecolare:3497.01Adrenotensin (human)
CAS:<p>Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.</p>Formula:C143H224N42O43Colore e forma:SolidPeso molecolare:3219.56AR ligand 40
<p>AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonistic activity. It exhibits antiproliferative effects on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells, with EC50 values of 7, 10, 12, 13, 15, and 39 μM, respectively.</p>Formula:C21H25N5Colore e forma:SolidPeso molecolare:347.211PAMP-12 (unmodified)
CAS:<p>PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from</p>Formula:C77H118N24O15Colore e forma:SolidPeso molecolare:1619.91Atrial natriuretic factor (1-28) (rat) TFA
<p>ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.</p>Formula:C130H206N45F3O41S2Purezza:98%Colore e forma:SolidPeso molecolare:3176.43PF-07062119
<p>PF-07062119 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody designed to target and inhibit GUCY2C.</p>Colore e forma:Odour LiquidOrforglipron hemicalcium hydrate
CAS:<p>Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].</p>Formula:C48H48F2N10O5Ca·H2OColore e forma:SolidPeso molecolare:921.02Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Formula:C128H216F3N45O36SColore e forma:SolidPeso molecolare:3050.42Amylin (8-37), human
CAS:<p>Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.</p>Formula:C138H216N42O45Colore e forma:SolidPeso molecolare:3183.4958-iso-15-keto Prostaglandin F2α
CAS:<p>8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans.</p>Formula:C20H32O5Colore e forma:SolidPeso molecolare:352.471Angiopeptin TFA
CAS:Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.Formula:C58H73F6N11O14S2Colore e forma:SolidPeso molecolare:1326.39M871
CAS:<p>GAL2 receptor antagonist; Ki: 13.1 nM (GAL2), 420 nM (GAL1); inhibits GAL2-induced pain.</p>Formula:C108H163N27O28Purezza:98%Colore e forma:SolidPeso molecolare:2287.64Prostaglandin F1α
CAS:<p>Prostaglandin F1α (PGF1α) is a lipid mediator and an endogenous metabolite of prostacyclin, regulate smooth muscle contraction.</p>Formula:C20H36O5Colore e forma:SolidPeso molecolare:356.5LP 12 hydrochloride
CAS:<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formula:C32H40ClN3OColore e forma:SolidPeso molecolare:518.14Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.Formula:C84H130F3N25O23S2Colore e forma:SolidPeso molecolare:1979.21Urocortin III (human)
CAS:<p>Urocortin III, a human peptide, binds CRF-R2, affecting insulin via somatostatin feedback with K i values 13.5-100+ nM.</p>Formula:C185H307N53O50S2Colore e forma:SolidPeso molecolare:4137.93Chemerin-9, Mouse
CAS:<p>Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.</p>Formula:C51H68N10O12Colore e forma:SolidPeso molecolare:1013.163Cloprostenol isopropyl ester
CAS:<p>(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.</p>Formula:C25H35ClO6Colore e forma:SolidPeso molecolare:466.99Cenderitide
CAS:<p>Cenderitide fuses CNP with DNP, stimulates pGC-A/B, ups cGMP, curbs aldosterone, and aids GFR, not affecting BP—used in heart failure studies.</p>Formula:C158H263N49O50S3Colore e forma:SolidPeso molecolare:3745.27[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
CAS:<p>[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a synthetic LHRH analog and a GnRH receptor antagonist.</p>Formula:C67H84N16O13Colore e forma:SolidPeso molecolare:1321.48Kisspeptin-10, human TFA
<p>"Kisspeptin-10, human TFA: vasoconstrictor, angiogenesis inhibitor, metastasis suppressor via GPR54, key in kidney development & osteoblast differentiation."</p>Formula:C63H83N17O14·C2HF3O2Colore e forma:SolidPeso molecolare:1416.46Retrobradykinin
CAS:<p>Bradykinin analog nonapeptide. Reverse sequence of Bradykinin. Exhibits no significant kinin activity. Can be used as a negative control.</p>Formula:C50H73N15O11Colore e forma:SolidPeso molecolare:1060.228hNTS1R agonist-1
<p>Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (</p>Formula:C37H62N10O9Purezza:98%Colore e forma:SolidPeso molecolare:790.95Bay 55-9837 TFA
<p>Bay 55-9837 TFA is a VPAC2 agonist with a 0.65 nM Kd, potential for type 2 diabetes research.</p>Formula:C150H240F3ClN44O44Colore e forma:SolidPeso molecolare:3456.22PY-60
CAS:<p>PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2).Cost-effective and quality-assured.</p>Formula:C16H15N3O2SPurezza:99.5% - 99.67%Colore e forma:SolidPeso molecolare:313.37Pramlintide TFA
Pramlintide TFA, a polypeptide analogue of human amylin and an antidiabetic agent, exhibits antineoplastic properties in colorectal cancer [1].Formula:C173H268N51F3O55S2Colore e forma:SolidPeso molecolare:4063.4Neuropeptide Y (2-36) (porcine)
CAS:<p>Porcine Neuropeptide Y (2-36) is 97.14% similar to rat/human, an agonist for Y5, Y2, Y1 receptors, used in obesity research.</p>Formula:C181H278N54O55Colore e forma:SolidPeso molecolare:4090.474-Chloromethamphetamine hydrochloride
CAS:<p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>Formula:C10H15Cl2NColore e forma:SolidPeso molecolare:220.14[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
CAS:<p>'[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)' is a selective NK2R agonist with prokinetic activity for smooth muscle studies.</p>Formula:C39H64N8O10Colore e forma:SolidPeso molecolare:804.97LY83583
CAS:<p>LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.</p>Formula:C15H10N2O2Purezza:99.54% - 99.80%Colore e forma:SolidPeso molecolare:250.25WAY-639418
CAS:<p>WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.</p>Formula:C17H16ClN5Purezza:99.62%Colore e forma:SolidPeso molecolare:325.8PSB-1114 triethylamine
<p>PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50</p>Formula:C10H15F2N3O13P3S·xC6H15NPurezza:98%Colore e forma:SolidThromboxane B1
CAS:<p>Thromboxane B1 (TXB1) is a lipid eicosanoid, part of the TXB family, involved in blood clotting.</p>Formula:C20H36O6Colore e forma:SolidPeso molecolare:372.5Corynanthine
CAS:<p>Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.</p>Formula:C21H26N2O3Purezza:98%Colore e forma:SolidPeso molecolare:354.44BAM (8-22) acetate
<p>BAM (8-22) acetate, a proenkephalin A derivative, stimulates MrgprC11, hMrgprX1, and causes scratching in mice.</p>Formula:C93H131N25O25SPurezza:98.85%Colore e forma:SolidPeso molecolare:2031.25Met-RANTES,human,acetate
<p>Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.</p>Colore e forma:Odour Solid[Ala11,D-Leu15]-Orexin B acetate
<p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>Formula:C122H210N44O37SPurezza:98.18%Colore e forma:SolidPeso molecolare:2917.31PG 106 acetate
<p>PG 106 acetate: Selective hMC3 receptor antagonist, IC50=210 nM; inactive on hMC5 and hMC4, EC50=9900 nM.</p>Formula:C53H73N13O11Purezza:98.24%Colore e forma:SolidPeso molecolare:1068.23Taspoglutide
CAS:<p>Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes</p>Formula:C152H232N40O45Purezza:98%Colore e forma:SolidPeso molecolare:3339.7633-Deoxyglucosone
CAS:<p>3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein</p>Formula:C6H10O5Purezza:95%Colore e forma:SolidPeso molecolare:162.14Benzquinamide
CAS:<p>Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer</p>Formula:C22H32N2O5Purezza:94.86%Colore e forma:SolidPeso molecolare:404.5
![[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76350.webp&w=3840&q=75)
![[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76426.webp&w=3840&q=75)
![[Ala11,D-Leu15]-Orexin B acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1975L.webp&w=3840&q=75)
