Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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5-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formula:C24H26N4O2SColore e forma:SolidPeso molecolare:434.55IRL-1620
CAS:<p>IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).</p>Formula:C86H117N17O27Purezza:98%Colore e forma:SolidPeso molecolare:1820.974Methapyrilene hydrochloride
CAS:<p>Methapyrilene hydrochloride is a biochemical.</p>Formula:C14H20ClN3SColore e forma:Liquid Solution) 5 5 (Ntp 1992)Peso molecolare:297.85Antibiotic Sch 60057
CAS:<p>Antibiotic Sch 60057 is a useful organic compound for research related to life sciences. The catalog number is T125403 and the CAS number is 203061-35-2.</p>Formula:C45H84O6Colore e forma:SolidPeso molecolare:721.161β-MSH, human
CAS:<p>beta-MSH, human is an endogenous peptide hormone and neurotransmitter by POMC, an agonist of MC4-R (melanocortin 4 receptor).</p>Formula:C118H174N34O35SPurezza:98%Colore e forma:SolidPeso molecolare:2660.924-P-PDOT
CAS:<p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>Formula:C19H21NOPurezza:99.91%Colore e forma:SolidPeso molecolare:279.38CTP-amiodarone
<p>CTP-amiodarone, a cellular-penetrating conjugate of myocardial cell-targeting peptide and Amiodarone, exhibits anti-arrhythmic activity by blocking Na+, K+, and Ca2+ channels as well as β-adrenergic receptors.</p>Formula:C97H131F3I2N20O25S2Colore e forma:SolidPeso molecolare:2352.13A 77636 hydrochloride
CAS:<p>A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).</p>Formula:C20H28ClNO3Purezza:99.57%Colore e forma:SolidPeso molecolare:365.89ELA-11(human)
CAS:<p>Apelin receptor agonist with high affinity (Ki = 14 nM). Blocks cAMP production and promotes β-arrestin activation; derived from ELA-32.</p>Formula:C58H90N16O13S2Purezza:98%Colore e forma:SolidPeso molecolare:1283.57M1145
CAS:<p>Potent GAL2 agonist with EC50 = 38 nM; Ki: 6.55 nM (GAL2), 497 nM (GAL3), 587 nM (GAL1); enhances galanin signaling.</p>Formula:C128H205N37O32Purezza:98%Colore e forma:SolidPeso molecolare:2774.26Amylin (1-37), human acetate
<p>Amylin (1-37), human acetate, a peptide hormone containing 37 amino acids secreted by the pancreas in conjunction with insulin, inhibits glucagon secretion.</p>Purezza:96.21%Colore e forma:Odour SolidHuman growth hormone-releasing factor
CAS:<p>GHRH from the hypothalamus prompts the pituitary to produce/release GH by attaching to the GHRHR.</p>Formula:C215H358N72O66SPurezza:98%Colore e forma:SolidPeso molecolare:5039.65Neurokinin B
CAS:<p>NKB, a tachykinin peptide, impacts human functions like gonadotropin-releasing hormone secretion.</p>Formula:C55H79N13O14S2Purezza:98%Colore e forma:SolidPeso molecolare:1210.42Mini Gastrin I, human
CAS:<p>Mini Gastrin I, human, is a truncated form of the human gastrin peptide, encompassing amino acids 5-17 of the original sequence.</p>Formula:C74H99N15O26SPurezza:98%Colore e forma:SolidPeso molecolare:1646.73Adrenomedullin (AM) (22-52), human TFA
<p>Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.</p>Formula:C161H253N46F3O50Purezza:98%Colore e forma:SolidPeso molecolare:3690.06Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Formula:C154H244N47F3O46S4Purezza:98%Colore e forma:SolidPeso molecolare:3675.12[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Formula:C74H112N22O18SPurezza:98%Colore e forma:SolidPeso molecolare:1629.88Urocortin III, mouse
CAS:<p>Mouse UcnIII, linked to stress behaviors, mainly occurs in the brain and rises in the hypothalamus post-restraint.</p>Formula:C186H312N52O52S2Purezza:98%Colore e forma:SolidPeso molecolare:4172.97(-)-Eseroline fumarate
CAS:<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Formula:C17H22N2O5Colore e forma:SolidPeso molecolare:334.37Somatostatin-28 (1-14)
CAS:<p>Somatostatin-28 (1-14) is a truncated neuropeptide from prosomatostatin cleavage.</p>Formula:C61H105N23O21SPurezza:98%Colore e forma:SolidPeso molecolare:1528.71Apadenoson TFA
<p>Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.</p>Formula:C25H31F3N6O8Purezza:98.08%Colore e forma:SoildPeso molecolare:600.55AR ligand 40
<p>AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonistic activity. It exhibits antiproliferative effects on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells, with EC50 values of 7, 10, 12, 13, 15, and 39 μM, respectively.</p>Formula:C21H25N5Colore e forma:SolidPeso molecolare:347.211GR 94800
CAS:<p>Potent and selective tachykinin NK2 receptor antagonist</p>Formula:C49H61N9O8Purezza:98%Colore e forma:SolidPeso molecolare:904.082Tienoxolol FA
<p>Tienoxolol FA, a beta-blocker for treating heart disease, hypertension, and ischemia.</p>Formula:C22H30N2O7SPurezza:97.05% - 98.85%Colore e forma:SoildPeso molecolare:466.55Minesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Formula:C21H31ClN4O5Purezza:99.85% - 99.88%Colore e forma:SolidPeso molecolare:454.95Gemeprost
CAS:<p>Gemeprost treats obstetric bleeding and induces abortion up to 24 weeks when used with mifepristone.</p>Formula:C23H38O5Purezza:98%Colore e forma:SolidPeso molecolare:394.54Neuropeptide Y (1-24) (human)
CAS:Neuropeptide Y (1-24) inhibits rat vas deferens twitch and activates NMDA-induced neurons in rat hippocampus.Formula:C116H170N30O40SPeso molecolare:2656.8319(S)-HETE
CAS:<p>19-HETE, a CYP450 arachidonic acid metabolite from kidneys, consists of 70% (S) and 30% (R) isomers and dilates renal vessels.</p>Formula:C20H32O3Colore e forma:SolidPeso molecolare:320.473SR-31747 free base
CAS:<p>SR-31747: immunosuppressive anti-inflammatory agent, inhibits cell growth by blocking sterol isomerase.</p>Formula:C23H34ClNColore e forma:SolidPeso molecolare:359.98Amisulpride hydrochloride
CAS:<p>Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.</p>Formula:C17H28ClN3O4SColore e forma:SolidPeso molecolare:405.94ALD1613
<p>ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.</p>Colore e forma:Odour LiquidCRF, bovine
CAS:<p>CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.</p>Formula:C206H340N60O63SPurezza:98%Colore e forma:SolidPeso molecolare:4697.34T-10430
<p>T-10430 is a potent and orally active agonist of the leukotriene B4 receptor 2 (BLT2). It shows potential for use in psoriasis research.</p>Formula:C17H22N6OColore e forma:SolidPeso molecolare:326.396ACTH (11-24)
CAS:<p>ACTH (11-24) is an adrenocorticotrophin fragment, stimulates cortisol, and antagonizes ACTH (1-39)/(1-10) in adrenal cells.</p>Formula:C77H134N24O16Purezza:98%Colore e forma:SolidPeso molecolare:1652.04[D-Leu6, Val7]-LH-RH (1-9) Ethyl Amide
[D-Leu6, Val7]-LH-RH (1-9) Ethyl Amide is a LHRH peptide analogue.Formula:C58H82N16O12Peso molecolare:1195.37Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Colore e forma:SolidPeso molecolare:355.38Linaclotide acetate
CAS:<p>Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.</p>Formula:C61H83N15O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1586.79Semaglutide, FITC labeled
Semaglutide (FITC-labeled Semaglutide) is a long-acting analog of human glucagon-like peptide-1, functioning as an agonist of the GLP-1 receptor. It shows potential for research related to type 2 diabetes.Formula:C209H304N46O63SPeso molecolare:4498.17191TAK-615
CAS:<p>TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.</p>Formula:C25H22FNO4Purezza:99.73%Colore e forma:SolidPeso molecolare:419.44ABT-702
CAS:<p>ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.</p>Formula:C22H19BrN6OPurezza:99.57%Colore e forma:SoildPeso molecolare:463.33Acetyl neurotensin (8-13)
CAS:Acetyl neurotensin (8-13), the most concise analog of neurotensin, retains complete binding and pharmacological properties [1].Formula:C40H66N12O9Peso molecolare:859.03GR 64349
CAS:<p>Potent NK2 agonist, EC50=3.7 nM in rat colon; >1000x selectivity over NK1, >300x over NK3; effective in vivo.</p>Formula:C42H68N10O11SPurezza:98%Colore e forma:SolidPeso molecolare:921.12Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formula:C26H31ClN2O4Colore e forma:SolidPeso molecolare:470.99p-MPPF
CAS:<p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>Formula:C25H27FN4O2Purezza:99.92%Colore e forma:SolidPeso molecolare:434.51Cetirizine methyl ester
CAS:<p>Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.</p>Formula:C22H27ClN2O3Colore e forma:SolidPeso molecolare:402.91GLP-1R agonist 16
CAS:<p>Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].</p>Formula:C50H58FN10O6PColore e forma:SolidPeso molecolare:945.03SB-206606
CAS:<p>SB-206606 is a novel, highly specific radioactive ligand for the β3-adrenergic receptor.</p>Formula:C19H22ClNO4Colore e forma:SolidPeso molecolare:363.83Anti-GLP-1R Antibody
<p>Anti-GLP-1R Antibody is an anti-GLP-1R antibody that can be used for immunohistochemistry of paraffin sections.</p>Purezza:98.3% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.3% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:Odour LiquidSpantide acetate
<p>Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.</p>Formula:C77H112N20O15Purezza:98.9200%Colore e forma:SolidPeso molecolare:1557.84PG106
CAS:<p>Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.</p>Formula:C51H69N13O9Purezza:98%Colore e forma:SolidPeso molecolare:1008.19
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