Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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SR-140603
CAS:<p>SR-140603, the less potent enantiomer of SR 140333, is used as the negative control.</p>Formula:C37H45Cl3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:656.12K-(D-1-Nal)-FwLL-NH2 TFA
<p>K-(D-1-Nal)-FwLL-NH2 TFA: potent ghrelin inverse agonist; Ki=4.9 nM (COS7), 31 nM (HEK293T); blocks Gq/G13 signaling.</p>Formula:C53H68F3N9O8Colore e forma:SolidPeso molecolare:1016.16(R,R)-Palonosetron Hydrochloride
CAS:<p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>Formula:C19H25ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:332.87ANQ-11125 TFA
<p>ANQ-11125 TFA is a motilin antagonist with a pKd of 8.24, inhibiting motilide contractions in rabbits.</p>Formula:C88H126F3N19O23Colore e forma:SolidPeso molecolare:1875.05JNJ-39933673
CAS:<p>JNJ-39933673 is a bio-active chemical.</p>Formula:C48H54F2N2O11Colore e forma:SolidPeso molecolare:872.96Secretin (28-54), human TFA
<p>Secretin (28-54), human TFA is a 27-amino acid peptide that works on the human Secretin receptor.</p>Formula:C132H221N44F3O42Purezza:98%Colore e forma:SolidPeso molecolare:3153.487-Hydroxy-PIPAT maleate
CAS:<p>7-Hydroxy-PIPAT maleate is a D3R agonist.</p>Formula:C16H22INOColore e forma:SolidPeso molecolare:371.262LY83583
CAS:<p>LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.</p>Formula:C15H10N2O2Purezza:99.54% - 99.80%Colore e forma:SolidPeso molecolare:250.25L-779976
CAS:<p>L-779,976 is an agonist of somatostatin receptor.</p>Formula:C33H43N7O3Colore e forma:SolidPeso molecolare:585.74Xaliproden
CAS:<p>Xaliproden is a biochemical.</p>Formula:C24H22F3NColore e forma:SolidPeso molecolare:381.43Dotanoc
CAS:<p>Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.</p>Formula:C69H94N14O17S2Colore e forma:SolidPeso molecolare:1455.71Tiaspirone hydrochloride
CAS:<p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>Formula:C24H33ClN4O2SPurezza:99.87%Colore e forma:SoildPeso molecolare:477.06Isobutyryl-L-carnitine
CAS:<p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>Formula:C11H21NO4Purezza:98%Colore e forma:SolidPeso molecolare:231.295-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Formula:C15H20N2OColore e forma:SolidPeso molecolare:244.33GIP/GLP-1 dual receptor agonist-1
CAS:<p>Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.</p>Colore e forma:SolidNoladin ether
CAS:<p>Noladin ether (2-AG ether) is a cannabinoid CB1 receptor agonist.</p>Formula:C23H40O3Colore e forma:SolidPeso molecolare:364.56Sauvagine
CAS:<p>CRF receptor agonist; Ki: 9.4 nM (hCRF-R1), 9.9 nM (rCRF-R2a), 3.8 nM (mCRF-R2b) for 125I-[D-Tyr1]astressin binding inhibition.</p>Formula:C202H346N56O63SPurezza:98%Colore e forma:SolidPeso molecolare:4599.35Calcitonin (human)
CAS:<p>Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.</p>Formula:C151H226N40O45S3Purezza:98%Colore e forma:White Lyophilized PowderPeso molecolare:3417.87FR190997
CAS:<p>FR190997 is an agonist of bradykinin B2 receptor.</p>Formula:C37H33Cl2N5O5Colore e forma:SolidPeso molecolare:698.59BAM(8-22) TFA
<p>BAM(8-22) TFA activates Mrgprs, induces mouse scratching, and is a proenkephalin A derivative.</p>Formula:C93H128F3N25O25SColore e forma:SolidPeso molecolare:2085.22AC-263093
CAS:<p>AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.</p>Formula:C8H8Br2N4Purezza:99.78%Colore e forma:SoildPeso molecolare:319.98tetranor-PGDM
CAS:<p>PGD2, made by H-PGDS in mast cells and lipocalin-PGD-synthase in the brain, aids sleep, cools the body, and inhibits platelet aggregation.</p>Formula:C16H24O7Colore e forma:SolidPeso molecolare:328.361PD 142893
CAS:<p>PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.</p>Formula:C50H65N7O10Purezza:98%Colore e forma:SolidPeso molecolare:924.09Secretin (33-59), rat TFA
<p>Secretin (33-59), rat (TFA), a 27-aa peptide, stimulates the secretin receptor, increasing pancreas secretion of bicarbonate, enzymes, and K+.</p>Formula:C131H217F3N42O44Colore e forma:SolidPeso molecolare:3141.37PSMA/GRPR ligand 1
<p>PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).</p>Colore e forma:Odour SolidNeurokinin B acetate(86933-75-7 free base)
<p>Neurokinin B acetate, a tachykinin, interacts with NK1R, NK2R, & NK3R receptors to exert biological effects.</p>Formula:C57H83N13O16S2Purezza:98.53%Colore e forma:SolidPeso molecolare:1270.48Ecraprost
CAS:<p>Ecraprost is used as a prodrug of prostaglandin E1.</p>Formula:C28H48O6Colore e forma:SolidPeso molecolare:480.68Hemokinin 1, human TFA
<p>Hemokinin-1 is a human TFA and selective NK1 agonist; also activates NK2 & NK3 and induces opioid-independent analgesia.</p>Formula:C56H85F3N14O16SColore e forma:SolidPeso molecolare:1299.42[Sar9] Substance P
CAS:<p>[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.</p>Formula:C64H100N18O13SPurezza:98%Colore e forma:SolidPeso molecolare:1361.66ALEPH hydrochloride
CAS:<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Formula:C12H20ClNO2SColore e forma:SolidPeso molecolare:277.81Metaraminol
CAS:<p>Metaraminol is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.</p>Formula:C9H13NO2Colore e forma:SolidPeso molecolare:167.21LRGILS-NH2
CAS:<p>LRGILS-NH2, reverse sequence of SLIGRL-NH2, is a control peptide for PAR2, affecting gut transit.</p>Formula:C29H56N10O7Purezza:98%Colore e forma:SolidPeso molecolare:656.82GLP-1R agonist 14
CAS:<p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>Formula:C45H42F2N10O5Colore e forma:SolidPeso molecolare:840.88β-CGRP (mouse)
<p>β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.</p>Formula:C165H265N49O55S2Colore e forma:SolidPeso molecolare:3879.29L-770644 dihydrochloride
CAS:<p>L-770644 dihydrochloride is a potent and selective agonist of the human beta3 adrenergic receptor.</p>Formula:C30H38ClN7O4SColore e forma:SolidPeso molecolare:628.19Neuropeptide W-30 (human)
CAS:<p>Neuropeptide W-30 (human) serves as a crucial stress mediator within the central nervous system, influencing the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. It acts as an endogenous ligand for the two related orphan G-protein-coupled receptors (GPCRs), GPR7 and GPR8, binding and activating them at comparable effective doses [1] [2] [3].</p>Formula:C165H249N49O37SColore e forma:SolidPeso molecolare:3543.119-deoxy-9-methylene Prostaglandin E2
CAS:<p>9-deoxy-9-methylene PGE2: stable PGE2 analog with similar effects, less side effects, equal potency in rats, gerbils, primates.</p>Formula:C21H34O4Colore e forma:SolidPeso molecolare:350.499Kisspeptin-10, human
CAS:<p>Kisspeptin-10, human is an effective vasoconstrictor and inhibitor of angiogenesis.</p>Formula:C63H83N17O14Purezza:98%Colore e forma:SolidPeso molecolare:1302.462(-)-Eseroline fumarate
CAS:<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Formula:C17H22N2O5Colore e forma:SolidPeso molecolare:334.37W140 HBr
CAS:<p>[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.</p>Formula:C16H28BrN2O4PPurezza:99.85%Colore e forma:SoildPeso molecolare:423.28ONO-0300302
CAS:<p>ONO-0300302: LPA1 antagonist, treats Benign Prostatic Hyperplasia, IC50 = 0.16 nM, reduces IUP in rats and dogs for 12h.</p>Formula:C29H35NO5Purezza:98%Colore e forma:SolidPeso molecolare:477.59O-2172
CAS:<p>O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).</p>Formula:C14H16Cl2O2Colore e forma:SolidPeso molecolare:287.18APJ receptor agonist 10
CAS:<p>APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.</p>Formula:C26H36N7O6SColore e forma:SolidPeso molecolare:574.67PG-931
CAS:<p>Selective MC4 agonist with IC50: 0.58 nM (MC4), 55 nM (MC3); revives heart/lung function in shocked rats.</p>Formula:C59H85N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1180.41PACAP (1-38) free acid
CAS:<p>PACAP (1-38) free acid, an endogenous neuropeptide, potently modulates gastrointestinal and neuroendocrine functions.</p>Colore e forma:SolidTGR5 agonist 7
<p>TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.</p>Formula:C37H59N2NaO9SColore e forma:SolidPeso molecolare:730.93GRK2i
CAS:<p>GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. Corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist.</p>Formula:C153H256N50O41SPurezza:98%Colore e forma:SolidPeso molecolare:3484.08Xanthine amine congener dihydrochloride
CAS:<p>XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.</p>Formula:C21H30Cl2N6O4Colore e forma:SolidPeso molecolare:501.41RF9
CAS:<p>RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively).</p>Formula:C26H38N6O3Purezza:98%Colore e forma:SolidPeso molecolare:482.62Halometasone
CAS:<p>Halometasone: synthetic corticosteroid for psoriasis and eczema treatment.</p>Formula:C22H27ClF2O5Colore e forma:SolidPeso molecolare:444.9
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