Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Obestatin(rat)
CAS:<p>Endogenous peptide that suppresses food intake and body weight-gain</p>Formula:C114H174N34O31Purezza:98%Colore e forma:SolidPeso molecolare:2516.81Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Colore e forma:SolidPeso molecolare:355.38DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Formula:C26H32BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:502.44Preclamol hydrochloride
CAS:<p>Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.</p>Formula:C14H22ClNOColore e forma:SolidPeso molecolare:255.78BQ-123 TFA
<p>BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.</p>Formula:C33H43F3N6O9Colore e forma:SolidPeso molecolare:724.72CAY10580
CAS:<p>CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).</p>Formula:C19H35NO4Colore e forma:SolidPeso molecolare:341.49GRL018-21
<p>GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].</p>Colore e forma:Odour SolidRelaxin H3 (human) TFA
<p>Relaxin H3 (human) (TFA) is a relaxin peptide that exerts antifibrotic effects through the RXFP1 receptor.</p>Formula:C237H374N70O69S6·xC2HF3O2Lys-Bradykinin
CAS:<p>Endogenous bradykinin receptor agonist</p>Formula:C56H85N17O12Purezza:98%Colore e forma:SolidPeso molecolare:1188.38(+)-OSU 6162
CAS:<p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>Formula:C15H23NO2SPurezza:98.19%Colore e forma:SoildPeso molecolare:281.41(3R,5R,6S)-Atogepant
<p>(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.</p>Formula:C29H23F6N5O3Colore e forma:SolidPeso molecolare:603.52S 16474
CAS:<p>S 16474 is an antagonist of Neurokinin-1 Receptor.</p>Formula:C44H48N6NaO8Purezza:98%Colore e forma:SolidPeso molecolare:811.892Imelciment
CAS:<p>Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.</p>Purezza:95%Colore e forma:Soild11-deoxy Prostaglandin E2
CAS:<p>11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.</p>Formula:C20H32O4Colore e forma:SolidPeso molecolare:336.47Heterobivalent ligand-1
<p>Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.</p>Formula:C86H115FN16O21Colore e forma:SolidPeso molecolare:1727.93L-803087 TFA
CAS:<p>L-803087 TFA: potent sst4 agonist, Ki=0.7 nM, >280x selective vs other somatostatin receptors; boosts AMPA, heightens seizures.</p>Formula:C27H30F5N5O5Colore e forma:SolidPeso molecolare:599.55Ilatreotide
CAS:<p>Ilatreotide is a Amadori compound of octreotide.</p>Formula:C61H86N10O20S2Purezza:98%Colore e forma:SolidPeso molecolare:1343.53M871
CAS:<p>GAL2 receptor antagonist; Ki: 13.1 nM (GAL2), 420 nM (GAL1); inhibits GAL2-induced pain.</p>Formula:C108H163N27O28Purezza:98%Colore e forma:SolidPeso molecolare:2287.64Protease-Activated Receptor-1 antagonist 2
CAS:<p>Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.</p>Formula:C24H23F2N3O2Colore e forma:SolidPeso molecolare:423.46SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColore e forma:SolidPeso molecolare:488.0412(S)-HpEPE
CAS:<p>12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.</p>Formula:C20H30O4Colore e forma:SolidPeso molecolare:334.456PSB 0777 ammonium salt
CAS:<p>adenosine A2A receptor full agonist</p>Formula:C18H24N6O7S2Purezza:98%Colore e forma:SolidPeso molecolare:500.55Kisspeptin-54(human) TFA
<p>Endogenous kisspeptin-54(human) TFA targets KISS1/GPR54 receptors; Ki: 1.81 nM (rat), 1.45 nM (human); inhibits metastasis, boosts gonadotropin.</p>Formula:C258H401N79O78·C2HF3O2Colore e forma:SolidPeso molecolare:5971.45CB2R probe 1
CAS:<p>CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of</p>Formula:C36H42N4O4Colore e forma:SolidPeso molecolare:594.74CRF(6-33)(human)
CAS:<p>CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.</p>Formula:C141H231N41O43SPurezza:98%Colore e forma:SolidPeso molecolare:3220.68L-threo Lysosphingomyelin (d18:1)
CAS:<p>L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).</p>Formula:C23H49N2O5PColore e forma:SolidPeso molecolare:464.62D5R agonist 1
<p>D5R Agonist 1 (Compound 5j) is a selective, orally active partial agonist of the D5 receptor that can penetrate the blood-brain barrier (EC50: 269.7 nM). It has been demonstrated to enhance cognitive abilities in a scopolamine-induced amnesia model.</p>Colore e forma:Odour SolidLP 12 hydrochloride
CAS:<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formula:C32H40ClN3OColore e forma:SolidPeso molecolare:518.14Efranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Colore e forma:LiquidMrgprX2 antagonist-2
CAS:<p>MrgprX2 antagonist-2, from patent WO2021092262A1 E163, is potent for skin inflammation studies.</p>Formula:C17H16F5N3O3Colore e forma:SolidPeso molecolare:405.325Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formula:C25H19D8N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:457.61Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurezza:98%Colore e forma:SolidPeso molecolare:306.5Lys-[Hyp3]-Bradykinin
CAS:<p>Lys-[Hyp3]-Bradykinin, a human urine-derived kinin and bradykinin agonist, is used for inflammation research.</p>Formula:C56H85N17O13Colore e forma:SolidPeso molecolare:1204.38[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:<p>Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.</p>Formula:C50H75N15O10Purezza:98%Colore e forma:SolidPeso molecolare:1046.23FR 113680
CAS:<p>FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.</p>Formula:C35H39N5O6Purezza:98%Colore e forma:SolidPeso molecolare:625.726RWJ 676070
CAS:<p>RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor.</p>Formula:C30H26ClFN2O5Colore e forma:SolidPeso molecolare:548.99Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
<p>Biotin-labeled GLP-1-(7-36) amide; a gut peptide that enhances insulin release.</p>Formula:C165H252N44O48SColore e forma:SolidPeso molecolare:3652.1Cyclic SSTR agonist octreotide
<p>Cyclic SSTR agonist octreotide is a Octreotide , serving as the cyclic Somatostatin Receptor SSTR agonist [1] .</p>Formula:C53H71N11O14S2Colore e forma:SolidPeso molecolare:1150.33TAK-683 acetate
<p>TAK-683 acetate: potent KISS1R agonist (IC50=170 pM), stable, nonapeptide. Affects GnRH, FSH, LH, testosterone; potential in prostate cancer research.</p>Formula:C66H87N17O15Colore e forma:SolidPeso molecolare:1358.5OXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:1749Baloncibart
CAS:<p>Baloncibart is a human IgG4K monoclonal antibody that targets NPR1.</p>Colore e forma:LiquidBradykinin (1-3)
CAS:<p>Bradykinin (1-3) is a fragment of Bradykinin. Bradykinin is an activates pain receptors.</p>Formula:C16H28N6O4Purezza:98%Colore e forma:SolidPeso molecolare:368.43Galcanezumab
CAS:<p>Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.</p>Purezza:> 95%Colore e forma:LiquidPeso molecolare:144.08 kDaNebentan
CAS:<p>Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.</p>Formula:C24H21N5O5SColore e forma:SolidPeso molecolare:491.52[Asu1,6-Arg8]Vasopressin
CAS:<p>[Asu1,6-Arg8]Vasopressin, a vasopressin agonist, boosts cAMP and ACTH release in cultured rat pituitary cells.</p>Formula:C48H68N14O12Colore e forma:SolidPeso molecolare:1033.14Bremelanotide
CAS:<p>Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.</p>Formula:C50H68N14O10Purezza:98%Colore e forma:White PowderPeso molecolare:1025.16GLP-1R agonist 29
<p>GLP-1R agonist 29 (Compound 20) is a GLP-1R agonist that induces hGLP-1R-mediated cAMP stimulation with an EC50 of 0.018 nM. It exhibits favorable pharmacokinetic properties and shows good in vivo exposure, with an AUC0-∞,sc of 77688 ng·h/mL.</p>Colore e forma:Odour SolidSynephrine hemitartrate
CAS:<p>Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.</p>Formula:C9H13NO2C4H6O6Colore e forma:SolidPeso molecolare:242.26Sarafotoxin S6c
CAS:<p>Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).</p>Formula:C103H147N27O37S5Purezza:98%Colore e forma:SolidPeso molecolare:2516SB-408124
CAS:<p>SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.</p>Formula:C19H18F2N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:356.37
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