Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Astressin acetate
<p>Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned</p>Formula:C163H273N49O44Purezza:96.87%Colore e forma:SolidPeso molecolare:3623.21Salmeterol
CAS:<p>Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.</p>Formula:C25H37NO4Purezza:99.2% - 99.9%Colore e forma:SolidPeso molecolare:415.57Senktide acetate
<p>Senktide acetate is a tachykinin NK3 receptor agonist that promotes the consolidation or expression of ELM and can be used to study Alzheimer's disease.</p>Formula:C42H59N7O13SPurezza:98.26%Colore e forma:SolidPeso molecolare:902.02Brefonalol HCl
<p>Brefonalol HCl, ADRA blocker for neurological/cardiovascular issues, treats angina, arrhythmias, hypertension.</p>Formula:C22H29ClN2O2Purezza:99.45%Colore e forma:SolidPeso molecolare:388.93Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Formula:C17H20N4SPurezza:99.86% - ≥95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:312.43Azatadine dimaleate
CAS:<p>Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.</p>Formula:C28H30N2O8Purezza:99.7% - >99.99%Colore e forma:PowderPeso molecolare:522.55Mifentidine
CAS:<p>Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers.</p>Formula:C13H16N4Purezza:98.34% - 99.73%Colore e forma:SolidPeso molecolare:228.29Lofepramine
CAS:<p>Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine.</p>Formula:C26H27ClN2OPurezza:98.38%Colore e forma:Crystals From Methanol Or Acetone SolidPeso molecolare:418.96Antazoline hydrochloride
CAS:<p>Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous</p>Formula:C17H19N3·HClPurezza:98% - 99.53%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:301.82Trazodone hydrochloride
CAS:<p>Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent.</p>Formula:C19H23Cl2N5OPurezza:99.5% - 99.52%Colore e forma:SolidPeso molecolare:408.33KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Formula:C26H40N4O8Purezza:98.46%Colore e forma:SolidPeso molecolare:536.62Nylidrin hydrochloride
CAS:<p>Nylidrin HCl inhibits IgG1-induced histamine release in guinea pigs and IgE-induced release in rat mast cells & human basophils.</p>Formula:C19H26ClNO2Purezza:99.35%Colore e forma:SolidPeso molecolare:335.87Bambuterol hydrochloride
CAS:<p>Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.</p>Formula:C18H30ClN3O5Purezza:99.53% - 99.61%Colore e forma:White SolidPeso molecolare:403.91Olinciguat
CAS:<p>Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.</p>Formula:C21H16F5N7O3Purezza:99.33% - 99.71%Colore e forma:SolidPeso molecolare:509.39Lafutidine
CAS:<p>Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.</p>Formula:C22H29N3O4SPurezza:98.55%Colore e forma:Yellowish White Crystalline PowderPeso molecolare:431.55Prucalopride
CAS:<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.</p>Formula:C18H26ClN3O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:367.87Venlafaxine hydrochloride
CAS:<p>Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.</p>Formula:C17H28ClNO2Purezza:97.32% - 99.86%Colore e forma:White Crystalline PowderPeso molecolare:313.86(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid
CAS:<p>(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.</p>Formula:C20H29N3O8Purezza:99.72%Colore e forma:SoildPeso molecolare:439.46Talastine
CAS:<p>Talastine is an antihistamine compound that can induce an allergic rash.</p>Formula:C19H21N3OPurezza:98.50% - 99.44%Colore e forma:SolidPeso molecolare:307.39Methyldopa
CAS:<p>Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or</p>Formula:C10H13NO4Purezza:98.95% - 99.86%Colore e forma:Less Or Almost Colorless Crystals Or White To Yellowish-White FinePeso molecolare:211.21Tropanserin
CAS:<p>Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.</p>Formula:C17H23NO2Purezza:99.74%Colore e forma:SolidPeso molecolare:273.37Talipexole dihydrochloride
CAS:<p>Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and</p>Formula:C10H17Cl2N3SPurezza:99.89%Colore e forma:Light Yellow SolidPeso molecolare:282.23Levodropropizine
CAS:<p>Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.</p>Formula:C13H20N2O2Purezza:99.87% - 99.93%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:236.31Clonidine hydrochloride
CAS:<p>Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.</p>Formula:C9H10Cl3N3Purezza:99.16% - 99.86%Colore e forma:SolidPeso molecolare:266.55Ro 10-5824 dihydrochloride
CAS:<p>Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM).</p>Formula:C17H22Cl2N4Purezza:99.79%Colore e forma:SolidPeso molecolare:353.29Rimonabant
CAS:<p>Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.</p>Formula:C22H21Cl3N4OPurezza:98% - 99.91%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:463.79NF-56-EJ40 hydrochloride
CAS:<p>NF-56-EJ40 HCl is a selective human SUCNR1 antagonist, IC50 = 25 nM, Ki = 33 nM; low rat SUCNR1 activity, Ki = 17.4 nM.</p>Formula:C27H31Cl2N3O3Purezza:99.33%Colore e forma:SoildPeso molecolare:516.46MP-A08
CAS:<p>MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.</p>Formula:C27H25N3O4S2Purezza:97.44%Colore e forma:SolidPeso molecolare:519.64Phenothiazine
CAS:<p>Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.</p>Formula:C12H9NSPurezza:99.95%Colore e forma:Yellow Solid PelletsPeso molecolare:199.27YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74Fluvoxamine maleate
CAS:<p>Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety</p>Formula:C19H25F3N2O6Purezza:99.92% - 99.94%Colore e forma:White Crystalline PowderPeso molecolare:434.41Silodosin
CAS:<p>Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.</p>Formula:C25H32F3N3O4Purezza:99.282% - 99.76%Colore e forma:Colorless To Pink SolidPeso molecolare:495.53Metaproterenol hemisulfate
CAS:<p>Metaproterenol hemisulfate (Orciprenaline sulfate) is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.</p>Formula:C11H17NO3·5H2O4SPurezza:98.53% - 99.74%Colore e forma:SolidPeso molecolare:260.3Cyproheptadine hydrochloride sesquihydrate
CAS:<p>Cyproheptadine hydrochloride sesquihydrate (Peritol), an antihistamine, is an antagonist of serotonin and histamine2.</p>Formula:C21H24ClNOPurezza:99.77% - >99.99%Colore e forma:White To Slightly Yellowish Crystalline SolidPeso molecolare:341.882-Bromo-6-methoxynaphthalene
CAS:<p>2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.</p>Formula:C11H9BrOPurezza:98.51%Colore e forma:White To Off-White PowderPeso molecolare:237.09Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Formula:C16H21N3O2Purezza:99.69% - 99.91%Colore e forma:White Or Kind Of White PowderPeso molecolare:287.36Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formula:C22H22FN3O3Purezza:99.19% - 99.73%Colore e forma:SolidPeso molecolare:395.43Chlorprothixene hydrochloride
CAS:<p>Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.</p>Formula:C18H18ClNS·HClPurezza:99.76%Colore e forma:White PowderPeso molecolare:352.32Amiselimod hydrochloride
CAS:<p>Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.</p>Formula:C19H31ClF3NO3Purezza:99.55%Colore e forma:SolidPeso molecolare:413.9Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Formula:C26H35NO7Purezza:98.53% - 99.43%Colore e forma:CoaPeso molecolare:473.57CYM 50769
CAS:<p>CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).</p>Formula:C24H17ClN2O3Purezza:98% - 99.08%Colore e forma:SolidPeso molecolare:416.86Ondansetron hydrochloride dihydrate
CAS:<p>Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.</p>Formula:C18H19N3O·HCl·2H2OPurezza:99.92%Colore e forma:White Crystal PowderPeso molecolare:365.86Fluparoxan hydrochloride
CAS:<p>Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Formula:C10H11ClFNO2Purezza:99.98%Colore e forma:SoildPeso molecolare:231.65Noradrenaline bitartrate
CAS:<p>Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors.</p>Formula:C12H19NO10Purezza:99.53% - >99.99%Colore e forma:SolidPeso molecolare:337.28hGPR91 antagonist 1
CAS:<p>hGPR91 antagonist 1 is a potent and selective hGPR91 antagonist (IC50: 7 μM).</p>Formula:C31H23F4N3OPurezza:98.89%Colore e forma:SolidPeso molecolare:529.53ML-180
CAS:<p>ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .</p>Formula:C20H25ClN4O2Purezza:99.74%Colore e forma:SolidPeso molecolare:388.89Levosulpiride
CAS:<p>Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.</p>Formula:C15H23N3O4SPurezza:98.20% - 99.88%Colore e forma:White Crystalline PowderPeso molecolare:341.43Acetophenazine dimaleate
CAS:<p>Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.</p>Formula:C31H37N3O10SPurezza:99.39% - 99.48%Colore e forma:SolidPeso molecolare:643.71JNJ-18038683
CAS:<p>JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.</p>Formula:C26H28ClN3O7Purezza:97.29%Colore e forma:SolidPeso molecolare:529.97DREADD agonist 21
CAS:<p>DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).</p>Formula:C17H18N4Purezza:99.94%Colore e forma:SolidPeso molecolare:278.35
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