Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Labetalol hydrochloride
CAS:<p>Labetalol hydrochloride (Sch-15719W), a salicylamide derivative, is a non-cardioselective blocker of β-adrenergic receptors and α1-adrenergic receptors.</p>Formula:C19H25ClN2O3Purezza:99.54% - 99.85%Colore e forma:SolidPeso molecolare:364.87Naluzotan hydrochloride
CAS:<p>Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 nM, Ki: ~5.1 nM), is used in anxiety and depression studies.</p>Formula:C23H39ClN4O3SPurezza:99.96%Colore e forma:SolidPeso molecolare:487.1Crotedumab
CAS:<p>Crotedumab (REGN1193) is a humanized antibody targeting GCGR, which reduces fasting blood glucose and improves glucose tolerance, used in diabetes research.</p>Purezza:>95%Colore e forma:LiquidFamotidine
CAS:<p>Famotidine, a histamine H2-blocker, curbs gastric acid production, lowering volume and acidity.</p>Formula:C8H15N7O2S3Purezza:98.93% - 99.91%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:337.45YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74Eletriptan hydrobromide
CAS:<p>Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.</p>Formula:C22H27BrN2O2SPurezza:99.69% - 99.85%Colore e forma:Tan SolidPeso molecolare:463.43Urocortin (rat) acetate
<p>Urocortin (rat) acetate: CRF receptor agonist; Ki=13nM (hCRF1), 1.5nM (rCRF2α), 0.97nM (mCRF2β); neuropeptide.</p>Purezza:97.76%Colore e forma:SoildDiphenylpyraline hydrochloride
CAS:<p>Diphenylpyraline hydrochloride treats Parkinsonism. It's an antihistamine with anticholinergic properties and inhibits dopamine reuptake.</p>Formula:C19H23NO·HClPurezza:98.72%Colore e forma:SolidPeso molecolare:317.85Itopride hydrochloride
CAS:<p>Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.</p>Formula:C20H27ClN2O4Purezza:99.59%Colore e forma:White Or Pale Brownish CrystalPeso molecolare:394.9Orforglipron
CAS:<p>Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1</p>Formula:C48H48F2N10O5Purezza:99.47% - 99.8%Colore e forma:SolidPeso molecolare:882.96CYM 50769
CAS:<p>CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).</p>Formula:C24H17ClN2O3Purezza:98% - 99.08%Colore e forma:SolidPeso molecolare:416.86Proglumide
CAS:<p>Proglumide (Binoside), an anti-ulcer drug, is a CCKA/CCKB antagonist that lowers gastric secretion and gastrointestinal motility.</p>Formula:C18H26N2O4Purezza:99.4% - 99.45%Colore e forma:White Crystalline PowderPeso molecolare:334.41Amitriptyline hydrochloride
CAS:<p>Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive</p>Formula:C20H24ClNPurezza:97% - 99.94%Colore e forma:Crystals White To Off-White PowderPeso molecolare:313.86Carebastine
CAS:<p>Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor.</p>Formula:C32H37NO4Purezza:99.16%Colore e forma:Off-White SolidPeso molecolare:499.64Ethamsylate
CAS:<p>Ethamsylate (Dicynene) 通常用作止血药，增加毛细血管内皮阻力和血小板粘附，抑制前列腺素的生物合成和作用。</p>Formula:C10H17NO5SPurezza:98.55%Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:263.31NF-56-EJ40 hydrochloride
CAS:<p>NF-56-EJ40 HCl is a selective human SUCNR1 antagonist, IC50 = 25 nM, Ki = 33 nM; low rat SUCNR1 activity, Ki = 17.4 nM.</p>Formula:C27H31Cl2N3O3Purezza:99.33%Colore e forma:SoildPeso molecolare:516.46hGPR91 antagonist 1
CAS:<p>hGPR91 antagonist 1 is a potent and selective hGPR91 antagonist (IC50: 7 μM).</p>Formula:C31H23F4N3OPurezza:98.89%Colore e forma:SolidPeso molecolare:529.53Alosetron hydrochloride
CAS:<p>Alosetron hydrochloride (GR 68755), a selective 5-HT3 receptor antagonist, can block the actions of serotonin at 5-HT3 sites in the peripheral nervous system.</p>Formula:C17H19ClN4OPurezza:99.90%Colore e forma:Off-White PowderPeso molecolare:330.81Clorprenaline hydrochloride
CAS:<p>Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.</p>Formula:C11H17Cl2NOPurezza:99.59% - >99.99%Colore e forma:SolidPeso molecolare:250.16Quercetin-3'-o-phosphate TEA
<p>Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA) is an adenosine A receptor antagonist that can be used to prevent and treat metabolic disorders.</p>Formula:C21H26NO10PPurezza:95.63%Colore e forma:SoildPeso molecolare:483.41Indacaterol maleate
CAS:<p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>Formula:C28H32N2O7Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:508.56Fenclozine Maleate
CAS:<p>Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain.</p>Formula:C45H47ClN2O12Purezza:98.47%Colore e forma:SoildPeso molecolare:843.314Tolazoline hydrochloride
CAS:<p>Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary</p>Formula:C10H13ClN2Purezza:99.67%Colore e forma:Pale Yellow Crystalline SolidPeso molecolare:196.68Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Formula:C19H21NSPurezza:99.93%Colore e forma:SolidPeso molecolare:295.44Nylidrin hydrochloride
CAS:<p>Nylidrin HCl inhibits IgG1-induced histamine release in guinea pigs and IgE-induced release in rat mast cells & human basophils.</p>Formula:C19H26ClNO2Purezza:99.35%Colore e forma:SolidPeso molecolare:335.87Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Formula:C17H20N4SPurezza:99.86% - ≥95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:312.43Dopexamine hydrochloride
CAS:<p>Dopexamine hydrochloride (FPL60278AR) is a β2-adrenoceptor agonist that modulates inflammation and protects organs without affecting hemodynamics.</p>Formula:C22H34Cl2N2O2Purezza:98.55%Colore e forma:SolidPeso molecolare:429.42RS 15385-198
CAS:<p>RS 15385-198 is a less active isomer of Delequamine. Delequamine is a selective alpha2-adrenergic receptor antagonist.</p>Formula:C18H26N2O3SPurezza:>99.99%Colore e forma:SoildPeso molecolare:350.48Bucumolol
CAS:<p>Bucumolol (Bucumarol) is a β-adrenergic blocking agent and a local anesthetic with antihypertensive activity and can be used to study myocardial infarction.</p>Formula:C17H23NO4Purezza:99.66%Colore e forma:SoildPeso molecolare:305.37Retatrutide
CAS:<p>Retatrutide (LY3437943) is a triple agonist of GCGR, GIPR and GLP-1R that can be used to study obesity.</p>Formula:C221H342N46O68Purezza:98.31%Colore e forma:SolidPeso molecolare:4732.092-Bromo-6-methoxynaphthalene
CAS:<p>2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.</p>Formula:C11H9BrOPurezza:98.51%Colore e forma:White To Off-White PowderPeso molecolare:237.09Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formula:C22H22FN3O3Purezza:99.19% - 99.73%Colore e forma:SolidPeso molecolare:395.43Prucalopride
CAS:<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.</p>Formula:C18H26ClN3O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:367.87ML-109
CAS:<p>ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)</p>Formula:C31H29N3O5Purezza:98.63%Colore e forma:SolidPeso molecolare:523.58Triflupromazine hydrochloride
CAS:<p>Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.</p>Formula:C18H20ClF3N2SPurezza:99.76% - 99.82%Colore e forma:CrystalsPeso molecolare:388.88MRGPRX1 agonist 1
CAS:<p>MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM).</p>Formula:C23H21N3O4SPurezza:99.95%Colore e forma:SolidPeso molecolare:435.5Bromperidol
CAS:<p>Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.</p>Formula:C21H23BrFNO2Purezza:99.89%Colore e forma:Tan SolidPeso molecolare:420.32Abarelix
CAS:<p>Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.</p>Formula:C72H95ClN14O14Purezza:>99.99%Colore e forma:SolidPeso molecolare:1416.06Centanafadine hydrochloride
CAS:Centanafadine HCl is a NE/DA reuptake inhibitor, also affects serotonin (IC50: NE 6 nM, DA 38 nM, serotonin 83 nM).Formula:C15H16ClNPurezza:99.65%Colore e forma:SolidPeso molecolare:245.75Alarelin Acetate
CAS:<p>Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.</p>Formula:C56H78N16O12Purezza:99.81% - >99.99%Colore e forma:White PowderPeso molecolare:1167.34Terbutaline
CAS:<p>Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol</p>Formula:C12H19NO3Purezza:99.12%Colore e forma:SolidPeso molecolare:225.3Adrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65Indusatumab
CAS:<p>Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody that can be used to synthesize antibody-drug conjugate.</p>Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.18 kDaAniracetam
CAS:<p>Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.</p>Formula:C12H13NO3Purezza:99.88% - 99.89%Colore e forma:White Crystalline Or Crystalline PowdePeso molecolare:219.24Pheniramine maleate
CAS:<p>Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.</p>Formula:C16H20N2·C4H4O4Purezza:99.85%Colore e forma:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CPeso molecolare:356.42Tegaserod maleate
CAS:<p>Tegaserod (SDZ-HTF-919), a 5-HT4 agonist for irritable bowel syndrome, was withdrawn by FDA on March 30, 2007, due to heart risk concerns.</p>Formula:C20H27N5O5Purezza:98% - 99.06%Colore e forma:White PowderPeso molecolare:417.46Talipexole dihydrochloride
CAS:<p>Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and</p>Formula:C10H17Cl2N3SPurezza:99.89%Colore e forma:Light Yellow SolidPeso molecolare:282.23Nicergoline
CAS:<p>Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.</p>Formula:C24H26BrN3O3Purezza:98% - 99.80%Colore e forma:SolidPeso molecolare:484.39Risperidone
CAS:<p>Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.</p>Formula:C23H27FN4O2Purezza:99.73%Colore e forma:Crystalline SolidPeso molecolare:410.48Aripiprazole Lauroxil
CAS:<p>Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic.</p>Formula:C36H51Cl2N3O4Purezza:99.64%Colore e forma:SolidPeso molecolare:660.71
