Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(942 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.949 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(149 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(410 prodotti)
- Recettore dell'endotelina(75 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(32 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(166 prodotti)
- Proteina Hedgehog/Smoothened(45 prodotti)
- Recettore dell'istamina(359 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(298 prodotti)
- PAFR(11 prodotti)
- PKA(49 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5378 prodotti di "Proteina G/GPCR"
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Exenatide
CAS:<p>Exenatide (Extendin-4) is a glucagon-like protein-1 (GLP-1) receptor agonist.</p>Formula:C186H286N50O62SPurezza:99.42%Colore e forma:SolidPeso molecolare:4247Benorilate
CAS:<p>Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.</p>Formula:C17H15NO5Purezza:98.39% - 99.85%Colore e forma:SolidPeso molecolare:313.3Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Formula:C27H34ClNO4Colore e forma:SolidPeso molecolare:472.02Clemizole
CAS:<p>Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.</p>Formula:C19H20ClN3Purezza:98% - 99.65%Colore e forma:SolidPeso molecolare:325.84Taladegib
CAS:<p>Taladegib (LY2940680), an oral Smo receptor antagonist, targets Hedgehog signaling for cancer treatment.</p>Formula:C26H24F4N6OPurezza:98.75% - >99.99%Colore e forma:SolidPeso molecolare:512.5Histrelin acetate
CAS:<p>Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency.</p>Formula:C68H90N18O14Purezza:99.92%Colore e forma:SolidPeso molecolare:1383.55MRT-10
CAS:<p>MRT-10 is a Smoothened (Smo) receptor antagonist.</p>Formula:C24H23N3O5SPurezza:99.73%Colore e forma:SolidPeso molecolare:465.52CCG215022
CAS:<p>CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.</p>Formula:C26H22FN7O3Purezza:97.63% - 99.69%Colore e forma:SolidPeso molecolare:499.5Clemizole hydrochloride
CAS:Clemizole hydrochloride blocks H1 histamine receptors and inhibits HCV replication and NS4B RNA binding.Formula:C19H21Cl2N3Purezza:>99.99%Colore e forma:SolidPeso molecolare:362.3PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41Mebhydrolin
CAS:<p>Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist.</p>Formula:C19H20N2Purezza:99.3% - ≥98%Colore e forma:SolidPeso molecolare:276.38LP-211
CAS:LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.Formula:C30H34N4OPurezza:98.65%Colore e forma:SolidPeso molecolare:466.62HhAntag
CAS:<p>HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity</p>Formula:C24H23ClN4O3Purezza:95.73%Colore e forma:SolidPeso molecolare:450.92BD 1008 dihydrobromide
CAS:<p>BD 1008 dihydrobromide: selective σ1 receptor antagonist (Ki=2 nM), high σ1 and moderate σ2 affinity.</p>Formula:C15H24Br2Cl2N2Purezza:97.81%Colore e forma:SolidPeso molecolare:463.08Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Formula:C20H24N2OSColore e forma:SolidPeso molecolare:340.48Cangrelor free acid
CAS:<p>Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.</p>Formula:C17H25Cl2F3N5O12P3S2Colore e forma:SolidPeso molecolare:776.36Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Formula:C20H25FN4OPurezza:99.56%Colore e forma:SolidPeso molecolare:356.44Picotamide
CAS:<p>Picotamide has anticoagulant and fibrinolytic properties.</p>Formula:C21H20N4O3Purezza:98.90%Colore e forma:SolidPeso molecolare:376.41Alosetron (Hydrochloride(1:X))
CAS:<p>Alosetron Hydrochloride is a selective 5-HT3 antagonist for treating IBS.</p>Formula:C17H18ClN4OColore e forma:SolidPeso molecolare:329.11691Rotigotine-
CAS:<p>Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.</p>Formula:C19H25NOSPurezza:98.08% - 99.59%Colore e forma:SolidPeso molecolare:315.47CYM50358
CAS:<p>N-(4-(aminomethyl)-2,6-dimethylphenyl)-5 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4).</p>Formula:C20H18Cl2N2O2Purezza:98.05% - 99.76%Colore e forma:SolidPeso molecolare:389.28Rimcazole dihydrochloride
CAS:<p>Rimcazole dihydrochloride: a σ receptor antagonist, hydrochloride salt, blocks dopamine uptake.</p>Formula:C21H28ClN3Purezza:99.63%Colore e forma:SolidPeso molecolare:357.92Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Formula:C13H16N2O2Purezza:98% - 99.89%Colore e forma:Pale Yellow Leaflets From Benzene SolidPeso molecolare:232.28GSK2018682
CAS:<p>GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).</p>Formula:C22H21ClN4O4Purezza:99.04%Colore e forma:SolidPeso molecolare:440.88RVD-Hpα acetate(1193362-76-3 free base)
<p>RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>Formula:C67H109N19O19Purezza:99.87%Colore e forma:SolidPeso molecolare:1484.71Tavapadon
CAS:<p>Tavapadon (CVL-751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist.</p>Formula:C19H16F3N3O3Purezza:99.33% - 99.8%Colore e forma:SolidPeso molecolare:391.34Conopressin S acetate(111317-90-9 free base)
<p>Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1b</p>Formula:C43H77N17O12S2Purezza:99.79%Colore e forma:SolidPeso molecolare:1088.32Tiprenolol
CAS:<p>Tiprenolol is a beta adrenergic receptor antagonist.[1]</p>Formula:C13H21NO2SPurezza:99.43%Colore e forma:SolidPeso molecolare:255.38Cyclopiazonic acid
CAS:<p>Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.</p>Formula:C20H20N2O3Purezza:99.27% - 99.80%Colore e forma:SolidPeso molecolare:336.38Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Formula:C24H22N4O5SPurezza:98.89% - 99.15%Colore e forma:SolidPeso molecolare:478.52LRGILS-NH2 acetate
<p>LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.</p>Formula:C29H56N10O7Purezza:96.65%Colore e forma:SolidPeso molecolare:656.82A-381393
CAS:<p>A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).</p>Formula:C20H24N4Purezza:99.00%Colore e forma:SolidPeso molecolare:320.43Fertirelin
CAS:<p>Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).</p>Formula:C55H76N16O12Purezza:>99.99%Colore e forma:SolidPeso molecolare:1153.29Reboxetine mesylate
CAS:<p>Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).</p>Formula:C19H23NO3·CH4O3SPurezza:99.18% - 99.87%Colore e forma:Tan Or Off-White Cyrstalline SolidPeso molecolare:409.5BQ-788 sodium salt
CAS:BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).Formula:C34H51N5NaO7Colore e forma:SolidPeso molecolare:664.8CYM-5541
CAS:<p>CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.</p>Formula:C19H28N2O2Purezza:99.74% - 99.76%Colore e forma:SolidPeso molecolare:316.44HTMT dimaleate
CAS:<p>HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) is an H1 and H2 receptor agonist.</p>Formula:C27H33F3N4O9Purezza:99.51%Colore e forma:SolidPeso molecolare:614.57Naluzotan
CAS:<p>Naluzotan（PRX 00023） is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+</p>Formula:C23H38N4O3SPurezza:>99.99%Colore e forma:SolidPeso molecolare:450.64Neuropeptide EI, rat acetate
Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.Formula:C65H102N16O25Purezza:95.55%Colore e forma:SolidPeso molecolare:1507.6SAX-187 hydrochloride
CAS:<p>WAY-181187 is a potent, selective 5-HT6 agonist with high affinity (2.2-4.8 nM), and increases GABA in rat cortex at 3-30 mg/kg s.c.</p>Formula:C15H14Cl2N4O2S2Colore e forma:SolidPeso molecolare:417.33(E)-3,4,5-Trimethoxycinnamic acid
CAS:<p>(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.</p>Formula:C12H14O5Purezza:99.83%Colore e forma:SolidPeso molecolare:238.24BCTC
CAS:<p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>Formula:C20H25ClN4OPurezza:99.21%Colore e forma:SolidPeso molecolare:372.89Tetrahydrozoline hydrochloride
CAS:Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity.Formula:C13H16N2·HClPurezza:99.90%Colore e forma:Off-White SolidPeso molecolare:236.74[Lys5,MeLeu9,Nle10]-NKA(4-10)
CAS:<p>Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).</p>Formula:C39H65N9O9Purezza:>99.99%Colore e forma:SolidPeso molecolare:803.99Lys-[Des-Arg9]Bradykinin,TFA
<p>Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2</p>Formula:C54H75F6N13O15Purezza:97.35%Colore e forma:SolidPeso molecolare:1260.24Netupitant
CAS:<p>Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).</p>Formula:C30H32F6N4OPurezza:99.43%Colore e forma:SolidPeso molecolare:578.59Guanfacine hydrochloride
CAS:<p>Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.</p>Formula:C9H10Cl3N3OPurezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:282.55Eltoprazine hydrochloride
CAS:<p>Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM,</p>Formula:C12H17ClN2O2Purezza:99.35%Colore e forma:SolidPeso molecolare:256.73Blarcamesine
CAS:<p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>Formula:C19H23NOPurezza:99.87%Colore e forma:SolidPeso molecolare:281.39REV 5901
CAS:<p>REV 5901: oral leukotriene receptor antagonist and 5-lipoxygenase inhibitor with Ki of 0.7 μM, researched for asthma.</p>Formula:C22H25NO2Colore e forma:SolidPeso molecolare:335.44
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