Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(942 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.949 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(149 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(410 prodotti)
- Recettore dell'endotelina(75 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(32 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(166 prodotti)
- Proteina Hedgehog/Smoothened(45 prodotti)
- Recettore dell'istamina(359 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(298 prodotti)
- PAFR(11 prodotti)
- PKA(49 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5378 prodotti di "Proteina G/GPCR"
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Atrasentan
CAS:Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.Formula:C29H38N2O6Purezza:97.65% - 99.08%Colore e forma:SolidPeso molecolare:510.62Pergolide
CAS:<p>Pergolide is a long-acting and orally active dopamine receptor D1/D2 agonist and ergoline derivative, used in the study of Parkinson's disease</p>Formula:C19H26N2SPurezza:99.95%Colore e forma:SolidPeso molecolare:314.49NPS ALX Compound 4a
CAS:NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)Formula:C25H25N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:431.55Mesdopetam hemitartrate
CAS:Mesdopetam hemitartrate antagonizes dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM) and stabilizes psychomotor function.Formula:C28H42F2N2O12S2Purezza:99.98%Colore e forma:SolidPeso molecolare:700.77Neuropeptide S (Rat) acetate
<p>Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor.</p>Formula:C97H164N34O29Purezza:95.36%Colore e forma:SolidPeso molecolare:2270.59Pramlintide acetate(151126-32-8 free base)
CAS:<p>Pramlintide acetate is a polypeptide analogue of human amylin. It serves as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer.</p>Formula:C173H271N51O55S2Purezza:>99.99%Colore e forma:SolidPeso molecolare:4009GLP-1(7-36), amide
CAS:GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.Formula:C149H226N40O45Purezza:99.85%Colore e forma:White PowderPeso molecolare:3297.63Ondansetron hydrochloride
CAS:<p>Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation</p>Formula:C18H19N3O·HClPurezza:99.78%Colore e forma:White PowderPeso molecolare:329.82Carbazochrome
CAS:<p>Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.</p>Formula:C10H12N4O3Purezza:98.36%Colore e forma:Nacarat Crystalline PowderPeso molecolare:236.23ML-18
CAS:<p>ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.</p>Formula:C32H35N5O5Purezza:98.62% - >99.99%Colore e forma:SolidPeso molecolare:569.65BRL-15572 dihydrochloride
CAS:<p>BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.</p>Formula:C25H27ClN2O·2HClPurezza:99.74%Colore e forma:SolidPeso molecolare:479.87Neuropeptide SF(mouse,rat) acetate
<p>Neuropeptide SF (mouse,rat) acetate is a NPFF receptor agonist with Ki of 48.4 nM (NPFF1) & 12.1 nM (NPFF2), enhancing ASIC3 current.</p>Formula:C42H69N13O12Purezza:98.37%Colore e forma:SolidPeso molecolare:948.08Quipazine maleate
CAS:<p>Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.</p>Formula:C17H19N3O4Colore e forma:SolidPeso molecolare:329.36Grapiprant
CAS:Grapiprant (AAT-007) is a selective EP4 receptor antagonist.Formula:C26H29N5O3SPurezza:99.49% - 99.843%Colore e forma:SolidPeso molecolare:491.61Tasimelteon
CAS:<p>Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.</p>Formula:C15H19NO2Purezza:98.93% - 99.93%Colore e forma:SolidPeso molecolare:245.32Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurezza:99.99%Colore e forma:Crystalline SolidPeso molecolare:327.90Loxapine
CAS:<p>Loxapine, a dibenzoxazepine antipsychotic, treats schizophrenia by blocking D2/D4 and serotonin receptors. Related to clozapine.</p>Formula:C18H18ClN3OPurezza:99.88%Colore e forma:Pale Yellowish Crystals From Petroleum Ether SolidPeso molecolare:327.81LIXIVAPTAN
CAS:<p>Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)</p>Formula:C27H21ClFN3O2Purezza:98.36%Colore e forma:SolidPeso molecolare:473.93CJC-1295 acetate(863288-34-0 free base)
<p>CJC-1295 acetate is a synthetic GHRH analogue and GHS.</p>Formula:C154H256N44O44Purezza:97.29%Colore e forma:SolidPeso molecolare:3428.01GBR 12935 dihydrochloride
CAS:GBR 12935 dihydrochloride (GBR 12935) can induce the increase of the extracellular levels of dopamine to basal levels.Formula:C28H36Cl2N2OPurezza:99.09% - ≥95%Colore e forma:SolidPeso molecolare:487.5Tesmilifene fumarate
CAS:<p>Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。</p>Formula:C23H29NO5Purezza:99.86%Colore e forma:SolidPeso molecolare:399.48Bepotastine
CAS:<p>Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.</p>Formula:C21H25ClN2O3Purezza:99.75%Colore e forma:SolidPeso molecolare:388.89Sitaxsentan sodium
CAS:Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.Formula:C18H14ClN2O6S2·NaPurezza:98.39% - 99.01%Colore e forma:SolidPeso molecolare:476.89CP 376395
CAS:<p>CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.</p>Formula:C21H30N2OPurezza:99.86% - 99.94%Colore e forma:SolidPeso molecolare:326.48CB1 antagonist 4
CAS:<p>TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.</p>Formula:C30H25Cl2F3N4OSPurezza:98.97%Colore e forma:SolidPeso molecolare:617.51Olcegepant
CAS:<p>Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4</p>Formula:C38H47Br2N9O5Purezza:96.08% - 97.24%Colore e forma:SolidPeso molecolare:869.65Substance P 1-9 aceate
<p>Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.</p>Formula:C54H81N15O14Purezza:99.01%Colore e forma:SolidPeso molecolare:1164.31Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Formula:C27H34ClNO4Colore e forma:SolidPeso molecolare:472.022-Pyridylethylamine dihydrochloride
CAS:<p>2-Pyridylethylamine dihydrochloride is a Histamine H1 receptor agonist.</p>Formula:C7H12Cl2N2Purezza:99.42%Colore e forma:SolidPeso molecolare:195.09Lurasidone hydrochloride
CAS:Lurasidone HCl: Atypical antipsychotic, treats schizophrenia & bipolar, affects dopamine, serotonin & adrenergic receptors.Formula:C28H36N4O2S·HClPurezza:99.51%Colore e forma:SolidPeso molecolare:529.14Volinanserin
CAS:Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.Formula:C22H28FNO3Purezza:98.94% - 99.95%Colore e forma:SolidPeso molecolare:373.46Atipamezole hydrochloride
CAS:<p>Atipamezole is a synthetic α2 adrenergic receptor antagonist.</p>Formula:C14H16N2·HClPurezza:99.74%Colore e forma:SolidPeso molecolare:248.75Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Formula:C8H10N4O2Purezza:98.37%Colore e forma:SolidPeso molecolare:194.19Protease-Activated Receptor-1, PAR-1 Agonist acetate
PAR-1 Agonist acetate is a selective PAR-1 agonist that mimics thrombin action.Formula:C37H62N10O11Purezza:98.1800%Colore e forma:SolidPeso molecolare:822.95Desmopressin acetate (16679-58-6 free base)
CAS:<p>Desmopressin (16679-58-6), a synthetic vasopressin analog, treats nocturia, enuresis, and diabetes insipidus by reducing urine production.</p>Formula:C48H68N14O14S2Purezza:98.84% - >99.99%Colore e forma:SolidPeso molecolare:1129.26Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Formula:C20H25FN4OPurezza:99.56%Colore e forma:SolidPeso molecolare:356.44Takeda103A
CAS:<p>Takeda103A (CMPD103A) is the GRK2-dependent bovine tubulin oxidation effective inhibitor.</p>Formula:C24H23F2N7OPurezza:97.17%Colore e forma:SolidPeso molecolare:463.48PNU-282987
CAS:<p>PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).</p>Formula:C14H18Cl2N2OPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:301.21RO1138452
CAS:<p>RO1138452 (CAY10441) blocks prostacyclin receptor; orally active, high affinity (Ki: 1.5 nM), analgesic in rats (2-20 mg/kg).</p>Formula:C19H23N3OPurezza:97.01% - 99.34%Colore e forma:SolidPeso molecolare:309.41Men 10376 TFA(135306-85-3,free)
<p>Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4</p>Formula:C59H69F3N12O12Purezza:99.22%Colore e forma:SolidPeso molecolare:1195.25AM966
CAS:<p>AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.</p>Formula:C27H23ClN2O5Purezza:98.06% - 99.79%Colore e forma:SolidPeso molecolare:490.93Ganirelix Acetate
CAS:<p>Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist</p>Formula:C82H117ClN18O15Purezza:96.05%Colore e forma:SolidPeso molecolare:1630.4Orexin B, rat, mouse Acetate
Orexin B, rat, mouse Acetate (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.Formula:C128H219N45O36SPurezza:94.61%Colore e forma:SolidPeso molecolare:2996.455-HT1A modulator 2 hydrochloride
CAS:<p>5-HT1A modulator 2 hydrochloride is a modulator of 5-HT1A showing an affinity of 53 nM for 5-HT1A binding.</p>Formula:C11H16ClNOPurezza:98.5%Colore e forma:SolidPeso molecolare:213.71-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
CAS:<p>1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.</p>Formula:C13H13NO5Purezza:99.55%Colore e forma:SolidPeso molecolare:263.25Etilevodopa hydrochloride
CAS:Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.Formula:C11H16ClNO4Purezza:95.00%Colore e forma:SolidPeso molecolare:261.7Darbufelone mesylate
CAS:Darbufelone mesylate blocks PGF2α, LTB4, PGHS-2 (IC50: 0.19 μM), and PGHS-1 (IC50: 20 μM).Formula:C19H28N2O5S2Purezza:96.81% - 99.92%Colore e forma:SolidPeso molecolare:428.57Guanabenz hydrochloride
CAS:Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.Formula:C8H9Cl3N4Purezza:99.45%Colore e forma:SolidPeso molecolare:267.54Substance P (7-11)
CAS:<p>Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .</p>Formula:C31H44N6O5SPurezza:98.39%Colore e forma:SolidPeso molecolare:612.78BAY 41-8543
CAS:<p>BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).</p>Formula:C21H21FN8OPurezza:99.86%Colore e forma:SolidPeso molecolare:420.44
![1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8913.webp&w=3840&q=75)
