Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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NIBR-0213
CAS:<p>NIBR-0213 is a potent and selective competitive S1P1 antagonist.Cost-effective and quality-assured.</p>Formula:C27H29ClN2O3Purezza:98.36% - 99.34%Colore e forma:SolidPeso molecolare:464.98Tolazoline
CAS:<p>Tolazoline (Benzalolin), a vasodilator, treats vessel spasms and reverses 5-HT2A drug overdose effects.</p>Formula:C10H12N2Purezza:99.52%Colore e forma:SolidPeso molecolare:160.22Serotonin
CAS:<p>Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. High-Quality, Low-Cost!</p>Formula:C10H12N2OPurezza:97.47% - 99.92%Colore e forma:SolidPeso molecolare:176.22tcY-NH2 TFA(327177-34-4 free base)
<p>tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.</p>Formula:C42H50F3N7O9Purezza:>99.99%Colore e forma:SolidPeso molecolare:853.9IPSU
CAS:<p>IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.</p>Formula:C23H27N5O2Purezza:97.05%Colore e forma:SolidPeso molecolare:405.49BD1063 dhydrochloride
CAS:<p>BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).</p>Formula:C13H20Cl4N2Purezza:99.52% - ≥95%Colore e forma:SolidPeso molecolare:346.12Conopressin S acetate(111317-90-9 free base)
<p>Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1b</p>Formula:C43H77N17O12S2Purezza:99.79%Colore e forma:SolidPeso molecolare:1088.32Thrombin Receptor Activator for Peptide
<p>Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.</p>Formula:C32H51F3N8O9Purezza:99.88%Colore e forma:SolidPeso molecolare:748.79Betaxolol
CAS:<p>Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.</p>Formula:C18H29NO3Purezza:99.01%Colore e forma:White Crystalline SolidPeso molecolare:307.43OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Formula:C79H125N23O22Purezza:98.52%Colore e forma:SolidPeso molecolare:1748.98MK-0557
CAS:<p>MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).</p>Formula:C22H19FN4O3Purezza:99.88%Colore e forma:SolidPeso molecolare:406.41Tetradecyl Phosphonate
CAS:<p>Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。</p>Formula:C14H31O3PPurezza:99.95%Colore e forma:White To Off-White PowderPeso molecolare:278.37CGS 21680 Hydrochloride
CAS:<p>CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.</p>Formula:C23H29N7O6·HClPurezza:96.74% - 99.53%Colore e forma:SolidPeso molecolare:535.98AZ3451
CAS:<p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>Formula:C30H27BrN4O3Purezza:98.12%Colore e forma:SolidPeso molecolare:571.46Reboxetine mesylate
CAS:<p>Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).</p>Formula:C19H23NO3·CH4O3SPurezza:99.18% - 99.87%Colore e forma:Tan Or Off-White Cyrstalline SolidPeso molecolare:409.5NNC-0640
CAS:<p>NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.</p>Formula:C29H31N7O4SPurezza:97.04%Colore e forma:SolidPeso molecolare:573.67Diquafosol tetrasodium
CAS:<p>Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film</p>Formula:C18H22N4Na4O23P4Purezza:98.25% - 99.97%Colore e forma:SolidPeso molecolare:878.23CAY10526
CAS:<p>CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.</p>Formula:C12H7BrO3SPurezza:98.75%Colore e forma:SolidPeso molecolare:311.15SCH442416
CAS:<p>SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).</p>Formula:C20H19N7O2Purezza:99.58%Colore e forma:SolidPeso molecolare:389.41M871 acetate
<p>M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptive</p>Formula:C110H167N27O30Purezza:99.84%Colore e forma:SolidPeso molecolare:2347.67Plecanatide
CAS:<p>Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.</p>Formula:C65H104N18O26S4Purezza:97.51%Colore e forma:SolidPeso molecolare:1681.89Metoclopramide hydrochloride hydrate
CAS:<p>Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction.</p>Formula:C14H25Cl2N3O3Purezza:99.33%Colore e forma:SolidPeso molecolare:354.27L-732138
CAS:<p>L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)</p>Formula:C22H18F6N2O3Purezza:99.77%Colore e forma:SolidPeso molecolare:472.38Indophagolin
CAS:<p>Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.</p>Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75Desmopressin acetate (16679-58-6 free base)
CAS:<p>Desmopressin (16679-58-6), a synthetic vasopressin analog, treats nocturia, enuresis, and diabetes insipidus by reducing urine production.</p>Formula:C48H68N14O14S2Purezza:98.84% - >99.99%Colore e forma:SolidPeso molecolare:1129.26Bay 55-9837 acetate
<p>Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.</p>Purezza:98.27%Colore e forma:LiquidPeso molecolare:N/AUrotensin I acetate (83930-33-0 Free base)
<p>Urotensin I acetate, CRF1/CRF2 agonist: pEC50s - hCRF1 11.46, hCRF2 9.36, rCRF2α 9.85; KIs - hCRF1 0.4 nM, rCRF2α 1.8 nM, mCRF2β 5.7 nM.</p>Purezza:95.44% - 96.09%Colore e forma:SolidPeso molecolare:N/APACAP 1-38 acetate
<p>PACAP 1-38 acetate, a PACAP analog, targets PACAP type I (IC50=4nM) and VIP2 receptors (IC50=1nM), not VIP1.</p>Purezza:98.16%Colore e forma:LiquidPeso molecolare:N/ARisperidone hydrochloride
CAS:<p>Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).</p>Formula:C23H28ClFN4O2Colore e forma:SolidPeso molecolare:446.95Decloxizine dihydrochloride
CAS:<p>Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist.</p>Formula:C21H28N2O2·2ClHPurezza:99.73%Colore e forma:SolidPeso molecolare:413.39AVN-492
CAS:<p>AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).</p>Formula:C17H21N5O2SPurezza:99.81%Colore e forma:SolidPeso molecolare:359.45Nonapeptide-1 acetate salt (158563-45-2 free base)
<p>Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH)</p>Formula:C63H91N15O11SPurezza:98.26%Colore e forma:SolidPeso molecolare:1266.58Adenosine amine congener
CAS:<p>Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.</p>Formula:C28H32N8O6Purezza:97.86%Colore e forma:SolidPeso molecolare:576.6(E)-3,4,5-Trimethoxycinnamic acid
CAS:<p>(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.</p>Formula:C12H14O5Purezza:99.83%Colore e forma:SolidPeso molecolare:238.24Ibrolipim
CAS:<p>Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.</p>Formula:C19H20BrN2O4PPurezza:98.04%Colore e forma:SolidPeso molecolare:451.25Siramesine
CAS:<p>Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent</p>Formula:C30H31FN2OPurezza:98%Colore e forma:SolidPeso molecolare:454.58[Sar9,Met(O2)11]-Substance P acetate
<p>[Sar9,Met(O2)11]-Substance P acetate is an NK1 agonist, raising MAP and HR equally to septide but with unique timing and behaviors.</p>Formula:C66H106N18O18SPurezza:>99.99%Colore e forma:SolidPeso molecolare:1471.75S26131
CAS:<p>S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki of</p>Formula:C31H34N2O4Purezza:99.77%Colore e forma:SolidPeso molecolare:498.61SB 204741
CAS:<p>SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.</p>Formula:C14H14N4OSPurezza:99.83%Colore e forma:SolidPeso molecolare:286.35BIM-23190 aceate
<p>BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.</p>Formula:C59H83N13O14S2Purezza:99.7%Colore e forma:SolidPeso molecolare:1262.5Montelukast
CAS:<p>Montelukast (Singular), oral asthma med, linked to rare liver injury.</p>Formula:C35H36ClNO3SPurezza:98.56% - >99.99%Colore e forma:SolidPeso molecolare:586.18(R)-Propranolol hydrochloride
CAS:<p>(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol.</p>Formula:C16H22ClNO2Purezza:98.63% - 99.01%Colore e forma:SolidPeso molecolare:295.8SHU 9119 acetate
<p>SHU 9119 acetate: hMC3R & hMC4R antagonist, hMC5R partial agonist. IC50: MC3R 0.23nM, MC4R 0.06nM, MC5R 0.09nM.</p>Formula:C56H75N15O11Purezza:99.8%Colore e forma:SolidPeso molecolare:1134.29Naftopidil dihydrochloride
CAS:<p>Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.</p>Formula:C24H28N2O3·2HClPurezza:99.76%Colore e forma:White SolidPeso molecolare:465.41Mebhydrolin
CAS:<p>Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist.</p>Formula:C19H20N2Purezza:99.3% - ≥98%Colore e forma:SolidPeso molecolare:276.38ACTH 11-24 acetate(4237-93-8 free base)
CAS:<p>ACTH 11-24 acetate is a cortisol-stimulating adrenocorticotrophin fragment and a competitive antagonist of ACTH 1-39 and 1-10.</p>Formula:C79H138N24O18Purezza:>99.99%Colore e forma:SolidPeso molecolare:1712.12Tasimelteon
CAS:<p>Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.</p>Formula:C15H19NO2Purezza:98.93% - 99.93%Colore e forma:SolidPeso molecolare:245.32Bupranolol
CAS:<p>Bupranolol blocks β2-adrenergic receptor; treats angina, hypertension, glaucoma, arrhythmia, and prevents clots.</p>Formula:C14H22ClNO2Purezza:97.63%Colore e forma:SolidPeso molecolare:271.78Naftopidil hydrochloride
CAS:<p>Naftopidil HCl (BM-15275) is a selective alpha1 blocker with Ki: α1a-3.7 nM, α1b-20 nM, α1d-1.2 nM; it also inhibits cell growth.</p>Formula:C24H29ClN2O3Purezza:99.5%Colore e forma:SolidPeso molecolare:428.95Aripiprazole monohydrate
CAS:<p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>Formula:C23H29Cl2N3O3Colore e forma:SolidPeso molecolare:466.4
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