Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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DORA-22
CAS:<p>DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory</p>Formula:C23H22F2N4O2Purezza:97.67%Colore e forma:SolidPeso molecolare:424.44Hemopressin (human, mouse) acetate
<p>Hemopressin: Nonapeptide, α1-hemoglobin derivative, CB1 inverse agonist, isolated from rats, oral, reduces inflammatory pain.</p>Formula:C52H83N13O14Purezza:99.86%Colore e forma:SolidPeso molecolare:1114.29A-836339
CAS:<p>A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.</p>Formula:C16H26N2O2SPurezza:99.94%Colore e forma:SolidPeso molecolare:310.45Peptide YY (PYY) (3-36), human
CAS:<p>Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.</p>Formula:C176H272N52O54Purezza:97.76%Colore e forma:SolidPeso molecolare:3980.42Emedastine
CAS:<p>Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.</p>Formula:C17H26N4OPurezza:97.1% - 97.76%Colore e forma:OilPeso molecolare:302.41CAY10526
CAS:<p>CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.</p>Formula:C12H7BrO3SPurezza:98.75%Colore e forma:SolidPeso molecolare:311.15Doxazosin
CAS:<p>Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.</p>Formula:C23H25N5O5Purezza:99.47% - 99.87%Colore e forma:SolidPeso molecolare:451.48Donitriptan Mesylate
CAS:<p>Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.</p>Formula:C24H29N5O5SColore e forma:SolidPeso molecolare:499.58CPI-444
CAS:<p>CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.</p>Formula:C20H21N7O3Purezza:98.78%Colore e forma:SolidPeso molecolare:407.43T-1095
CAS:<p>T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).</p>Formula:C26H28O11Purezza:99.78%Colore e forma:SolidPeso molecolare:516.49Ropinirole hydrochloride
CAS:<p>Ropinirole HCl (SKF-101468A) is a selective D2 dopamine agonist (Ki: 29 nM) with antiparkinsonian effects.</p>Formula:C16H24N2O·HClPurezza:99.87% - 99.98%Colore e forma:Off-White SolidPeso molecolare:296.84HAEGTFT acetate(926018-95-3 free base)
<p>HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.</p>Formula:C35H51N9O14Purezza:>99.99%Colore e forma:SolidPeso molecolare:821.84Linzagolix
CAS:<p>Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei</p>Formula:C22H15F3N2O7SPurezza:99.33%Colore e forma:SolidPeso molecolare:508.42CB1-IN-1
CAS:<p>CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.</p>Formula:C33H31Cl2F3N6O3S2Purezza:99.08% - 99.76%Colore e forma:SolidPeso molecolare:751.67S 14506 HCl
CAS:<p>S 14506 HCl: Strong 5-HT1A agonist; pKi - 9.0 (5-HT1A), 6.6 (5-HT1B/C), <6.0 (5-HT3).</p>Formula:C24H26FN3O2Colore e forma:SolidPeso molecolare:407.48Pancreatic Polypeptide (human) acetate
<p>Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.</p>Purezza:97.26%Colore e forma:LiquidPeso molecolare:N/AH2L 5765834
CAS:<p>H2L 5765834 is a lysophosphatidic acid receptors antagonist</p>Formula:C21H12N2O7Purezza:98.25% - 99.47%Colore e forma:SolidPeso molecolare:404.33Antalarmin
CAS:<p>Antalarmin is a CRHR1 antagonist that blocks adrenocorticotropin-releasing hormone-induced hypertension, blocks CRF activation.</p>Formula:C24H34N4Colore e forma:SolidPeso molecolare:378.55Montelukast dicyclohexylamine
CAS:<p>Montelukast (MK0476), a selective CysLT1 antagonist, treats asthma, liver injury, and is researched for COVID-19.</p>Formula:C47H59ClN2O3SColore e forma:SolidPeso molecolare:767.5Ciliobrevin A
CAS:<p>Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.</p>Formula:C17H9Cl2N3O2Purezza:98.54% - 99.57%Colore e forma:SolidPeso molecolare:358.18Tianeptine
CAS:<p>Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H25ClN2O4SPurezza:99.04%Colore e forma:SolidPeso molecolare:436.95PD-168077 maleate
CAS:<p>PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)</p>Formula:C24H26N4O5Purezza:99.13%Colore e forma:SolidPeso molecolare:450.49Verucerfont
CAS:<p>Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .</p>Formula:C22H26N6O2Purezza:99.90%Colore e forma:SolidPeso molecolare:406.48JNJ-31020028
CAS:<p>JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity (pIC50=8.07, human; pIC50=8.22, rat).</p>Formula:C34H36FN5O2Purezza:95.92% - 99.65%Colore e forma:SolidPeso molecolare:565.68Serotonin
CAS:<p>Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. High-Quality, Low-Cost!</p>Formula:C10H12N2OPurezza:97.47% - 99.92%Colore e forma:SolidPeso molecolare:176.22Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Formula:C13H16N2O2Purezza:98% - 99.89%Colore e forma:Pale Yellow Leaflets From Benzene SolidPeso molecolare:232.28SAG
CAS:<p>SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective.</p>Formula:C28H28ClN3OSPurezza:97.37% - 98.88%Colore e forma:SolidPeso molecolare:490.06Neuropeptide S (Rat) acetate
<p>Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor.</p>Formula:C97H164N34O29Purezza:95.36%Colore e forma:SolidPeso molecolare:2270.59Sarpogrelate hydrochloride
CAS:<p>Sarpogrelate hydrochloride (MCI-9042), a 5-HT2 antagonist with high affinity (Ki=8.39nM), is used as an anti-platelet for PAD, improving vascular function.</p>Formula:C24H32ClNO6Purezza:99.73%Colore e forma:Colorless LiquidPeso molecolare:465.97Endothelin-2 (49-69), human
CAS:<p>Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.</p>Formula:C115H160N26O32S4Purezza:98.26%Colore e forma:SolidPeso molecolare:2546.92BRL-15572 dihydrochloride
CAS:<p>BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.</p>Formula:C25H27ClN2O·2HClPurezza:99.74%Colore e forma:SolidPeso molecolare:479.87AC-55541
CAS:<p>AC-55541 (AOB2796), a PAR2 agonist, activates PAR2 in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays.</p>Formula:C25H20BrN5O3Purezza:98% - 99.33%Colore e forma:SolidPeso molecolare:518.36GRA Ex-25
CAS:<p>GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.</p>Formula:C29H36F3N3O5Purezza:98.2% - 98.88%Colore e forma:SolidPeso molecolare:563.61Cinitapride
CAS:<p>Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.</p>Formula:C21H30N4O4Purezza:99.52%Colore e forma:SolidPeso molecolare:402.49CGS 21680 Hydrochloride
CAS:<p>CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.</p>Formula:C23H29N7O6·HClPurezza:96.74% - 99.53%Colore e forma:SolidPeso molecolare:535.98Betaxolol
CAS:<p>Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.</p>Formula:C18H29NO3Purezza:99.01%Colore e forma:White Crystalline SolidPeso molecolare:307.43Chlorpheniramine
CAS:<p>Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.</p>Formula:C16H19ClN2Colore e forma:SolidPeso molecolare:274.79BRL-15572 hydrochloride
CAS:<p>BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.</p>Formula:C25H28Cl2N2OColore e forma:SolidPeso molecolare:443.41ONO-7300243
CAS:<p>ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).</p>Formula:C28H31NO5Purezza:99.66%Colore e forma:SolidPeso molecolare:461.55Lidamidine Hydrochloride
CAS:<p>Lidamidine HCl: α2-adrenergic agonist; lowers gut secretion, slows transit, stops muscle contractions.</p>Formula:C11H17ClN4OColore e forma:SolidPeso molecolare:256.73DPCPX
CAS:<p>DPCPX (PD 116948) is an A1 adenosine receptor antagonist</p>Formula:C16H24N4O2Purezza:99.23% - 99.93%Colore e forma:White SolidPeso molecolare:304.39ZK 756326
CAS:<p>ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.</p>Formula:C21H28N2O3Purezza:99.43%Colore e forma:SolidPeso molecolare:356.46RBC8
CAS:<p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>Formula:C25H20N4O3Purezza:98.44% - 99.81%Colore e forma:SolidPeso molecolare:424.45ML 154
CAS:<p>ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.</p>Formula:C29H26BrN2PSPurezza:99.53%Colore e forma:SolidPeso molecolare:545.47SBI-115
CAS:<p>SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5</p>Formula:C14H13ClN2O4SPurezza:99.53% - 99.78%Colore e forma:SolidPeso molecolare:340.78Pranlukast hemihydrate
CAS:<p>Pranlukast hemihydrate (ONO-1078 hemihydrate) is an LT antagonist with anti-asthmatic activity.</p>Formula:C27H23N5O40·5H2OPurezza:99.28%Colore e forma:SolidPeso molecolare:490.52Dasotraline
CAS:<p>Dasotraline: a triple reuptake inhibitor targeting DA, NE, and 5-HT with IC50 values of 4, 6, 11 nM. Possible new antidepressant class.</p>Formula:C16H15Cl2NColore e forma:SolidPeso molecolare:292.2Zacopride hydrochloride
CAS:<p>Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.</p>Formula:C15H20ClN3O2·HClPurezza:98.32%Colore e forma:SolidPeso molecolare:346.26Vercirnon sodium
CAS:<p>Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.</p>Formula:C22H21ClN2NaO4SColore e forma:SolidPeso molecolare:467.92Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurezza:99.99%Colore e forma:Crystalline SolidPeso molecolare:327.90
