Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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[Des-Arg9]-Bradykinin TFA
CAS:<p>[Des-Arg9]-Bradykinin is an agonist of Bradykinin (B1) receptor that displays selectivity for B1 over B2 receptors.</p>Formula:C46H62F3N11O12Purezza:>99.99%Colore e forma:SolidPeso molecolare:1018.05Brefonalol
CAS:<p>Brefonalol is a vasodilating beta-adrenergic receptor blocker.</p>Formula:C22H28N2O2Colore e forma:SolidPeso molecolare:352.47AdipoRon
CAS:<p>AdipoRon (SC-396658) is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).</p>Formula:C27H28N2O3Purezza:97.90% - 99.86%Colore e forma:SolidPeso molecolare:428.52Canagliflozin
CAS:<p>Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.</p>Formula:C24H25FO5SPurezza:98.01% - >99.99%Colore e forma:SolidPeso molecolare:444.52ML-184
CAS:<p>ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM.</p>Formula:C25H34N4O3SPurezza:99.45%Colore e forma:SolidPeso molecolare:470.63ML-18
CAS:<p>ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.</p>Formula:C32H35N5O5Purezza:98.62% - >99.99%Colore e forma:SolidPeso molecolare:569.65CAY10526
CAS:<p>CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.</p>Formula:C12H7BrO3SPurezza:98.75%Colore e forma:SolidPeso molecolare:311.15Men 10376 TFA(135306-85-3,free)
<p>Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4</p>Formula:C59H69F3N12O12Purezza:99.22%Colore e forma:SolidPeso molecolare:1195.25Bretylium tosylate
CAS:<p>Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.</p>Formula:C18H24BrNO3SPurezza:>99.99%Colore e forma:SolidPeso molecolare:414.36Urotensin I acetate (83930-33-0 Free base)
<p>Urotensin I acetate, CRF1/CRF2 agonist: pEC50s - hCRF1 11.46, hCRF2 9.36, rCRF2α 9.85; KIs - hCRF1 0.4 nM, rCRF2α 1.8 nM, mCRF2β 5.7 nM.</p>Purezza:95.44% - 96.09%Colore e forma:SolidPeso molecolare:N/AGSK 789472 hydrochloride
CAS:<p>GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.</p>Formula:C15H22ClN3OPurezza:99.89%Colore e forma:SolidPeso molecolare:295.81BD 1008 dihydrobromide
CAS:<p>BD 1008 dihydrobromide: selective σ1 receptor antagonist (Ki=2 nM), high σ1 and moderate σ2 affinity.</p>Formula:C15H24Br2Cl2N2Purezza:97.81%Colore e forma:SolidPeso molecolare:463.08CB1 antagonist 4
CAS:<p>TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.</p>Formula:C30H25Cl2F3N4OSPurezza:98.97%Colore e forma:SolidPeso molecolare:617.51BCTC
CAS:<p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>Formula:C20H25ClN4OPurezza:99.21%Colore e forma:SolidPeso molecolare:372.89Neurotensin
CAS:Neurotensin, a 13 amino acid peptide, regulates LH and prolactin, interacts with dopamine system.Formula:C78H121N21O20Purezza:>99.99%Colore e forma:SolidPeso molecolare:1672.929-FLUORENOL
CAS:<p>9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.</p>Formula:C13H10OPurezza:99.98%Colore e forma:Off-White Crystalline PowderPeso molecolare:182.22Conivaptan hydrochloride
CAS:<p>Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and</p>Formula:C32H26N4O2·HClPurezza:98.33% - 99.86%Colore e forma:SolidPeso molecolare:535.04MRT-10
CAS:<p>MRT-10 is a Smoothened (Smo) receptor antagonist.</p>Formula:C24H23N3O5SPurezza:99.73%Colore e forma:SolidPeso molecolare:465.52Sarpogrelate
CAS:<p>Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.</p>Formula:C24H31NO6Colore e forma:SolidPeso molecolare:429.51Ritanserin
CAS:<p>Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.</p>Formula:C27H25F2N3OSPurezza:99.77% - 99.89%Colore e forma:SolidPeso molecolare:477.57M 1145 acetate
<p>M1145 acetate: chimeric peptide, selective GAL2 agonist, Ki=6.55 nM; >90x affinity vs GAL1, 76x vs GalR3. Enhances galanin signal.</p>Formula:C130H209N37O34Purezza:99.1%Colore e forma:SolidPeso molecolare:2834.28Mequitazine
CAS:<p>Mequitazine (Virginan) is an effective, nonsedative and long-acting histamine H1 antagonist.</p>Formula:C20H22N2SPurezza:99.98%Colore e forma:SolidPeso molecolare:322.47Ipsapirone hydrochloride
CAS:<p>Ipsapirone, a pyrimidinylpiperazine ligand, is potent and specific for 5-HT1A receptors and has potential therapeutic use in affective disorders.</p>Formula:C19H24ClN5O3SColore e forma:SolidPeso molecolare:437.94MK 571
CAS:<p>MK 571 (L660711) is an orally active antagonist of CysLT1 receptor.</p>Formula:C26H27ClN2O3S2Purezza:98.69% - 99.65%Colore e forma:SolidPeso molecolare:515.09Cenicriviroc
CAS:<p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>Formula:C41H52N4O4SPurezza:97.87%Colore e forma:SolidPeso molecolare:696.94Maraviroc
CAS:<p>Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.</p>Formula:C29H41F2N5OPurezza:97.13% - 99.59%Colore e forma:Brown SolidPeso molecolare:513.67Tripelennamine citrate
CAS:<p>Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.</p>Formula:C22H29N3O7Colore e forma:SolidPeso molecolare:447.488Chlorprothixene
CAS:<p>Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.</p>Formula:C18H18ClNSPurezza:98.77% - 99.756%Colore e forma:Pale Yellow Crystals SolidPeso molecolare:315.86Triprolidine hydrochloride
CAS:<p>Triprolidine hydrochloride anhydrous, a Histamine H1 antagonist, is used in asthma, allergic rhinitis, and urticaria.</p>Formula:C19H23ClN2Colore e forma:SolidPeso molecolare:314.852[D-Phe12,Leu14]-Bombesin acetate
<p>[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.</p>Formula:C77H118N22O20Purezza:98.41% - 99.14%Colore e forma:SolidPeso molecolare:1671.9Reboxetine mesylate
CAS:<p>Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).</p>Formula:C19H23NO3·CH4O3SPurezza:99.18% - 99.87%Colore e forma:Tan Or Off-White Cyrstalline SolidPeso molecolare:409.5MHP
CAS:<p>MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.</p>Formula:C16H23NO4Purezza:98.58%Colore e forma:SolidPeso molecolare:293.36RS 100329
CAS:<p>RS 100329 HCl is a selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors).</p>Formula:C20H25F3N4O3Colore e forma:SolidPeso molecolare:426.43C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purezza:99.74% - 99.90%Colore e forma:SolidPeso molecolare:467.65nifenalol.HCl
CAS:<p>Nifenalol.HCl(INPEA) is a antagonist of β-adrenergic receptor.</p>Formula:C11H17ClN2O3Purezza:99.96%Colore e forma:SolidPeso molecolare:260.72M40 acetate(143896-17-7 free base)
<p>M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29)</p>Formula:C96H149N23O26Purezza:99.88%Colore e forma:SolidPeso molecolare:2041.38HCGRP-(8-37) acetate
<p>HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.</p>Formula:C141H234N44O40Purezza:99.29%Colore e forma:SolidPeso molecolare:3185.64DORA-22
CAS:<p>DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory</p>Formula:C23H22F2N4O2Purezza:97.67%Colore e forma:SolidPeso molecolare:424.44VKGILS-NH2 Acetate
<p>VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.</p>Formula:C30H58N8O9Purezza:98.83%Colore e forma:SolidPeso molecolare:674.831-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:<p>1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.</p>Formula:C9H15N3OPurezza:95%Colore e forma:SolidPeso molecolare:181.23AZD-4818
CAS:<p>AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Formula:C27H32Cl2N2O7Purezza:99.01%Colore e forma:SolidPeso molecolare:567.46Bevantolol hydrochloride
CAS:<p>Bevantolol hydrochloride (NC-1400 hydrochloride) is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.</p>Formula:C20H28ClNO4Purezza:99.49%Colore e forma:SolidPeso molecolare:381.9AM1241
CAS:<p>AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.</p>Formula:C22H22IN3O3Purezza:98.937% - 99.1%Colore e forma:SolidPeso molecolare:503.33JK184
CAS:<p>JK184 is a potent Hedgehog (Hh) pathway inhibitor.</p>Formula:C19H18N4OSPurezza:98.93% - 99.89%Colore e forma:SolidPeso molecolare:350.442-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Formula:C38H64F3N11O10Purezza:>99.99%Colore e forma:SolidPeso molecolare:891.98Afamelanotide acetate
CAS:<p>Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist.</p>Formula:C80H115N21O21Purezza:98% - 99.494%Colore e forma:SolidPeso molecolare:1706.94i
CAS:<p>4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.</p>Formula:C16H12ClN3OPurezza:99.49%Colore e forma:SolidPeso molecolare:297.74Alizapride hydrochloride
CAS:<p>Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.</p>Formula:C16H21N5O2·HClPurezza:99.35% - 99.48%Colore e forma:CoaPeso molecolare:351.83Bromodiphenhydramine hydrochloride
CAS:<p>Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.</p>Formula:C17H21BrClNOPurezza:97.29%Colore e forma:SolidPeso molecolare:370.71SB-334867 free base
CAS:<p>SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.</p>Formula:C17H13N5O2Purezza:99.67% - >99.99%Colore e forma:SolidPeso molecolare:319.32
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