Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(993 prodotti)
- Recettore dell'adenosina(246 prodotti)
- Recettore adrenergico(3.004 prodotti)
- Recettore della bombesina(33 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(153 prodotti)
- CaSR(33 prodotti)
- Recettore dei cannabinoidi(212 prodotti)
- Recettore della dopamina(433 prodotti)
- Recettore dell'endotelina(79 prodotti)
- Recettore GNRH(77 prodotti)
- GPCR19(32 prodotti)
- GRK(32 prodotti)
- GTPase(22 prodotti)
- Recettore del glucagone(182 prodotti)
- Proteina Hedgehog/Smoothened(47 prodotti)
- Recettore dell'istamina(381 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(310 prodotti)
- PAFR(12 prodotti)
- PKA(51 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5745 prodotti di "Proteina G/GPCR"
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(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid
CAS:(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.Formula:C20H29N3O8Purezza:99.72%Colore e forma:SoildPeso molecolare:439.46Fluphenazine dihydrochloride
CAS:Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR. Fluphenazine can be used to probe effects and metabolic process.Formula:C22H28Cl2F3N3OSPurezza:99.23%Colore e forma:Off-White SolidPeso molecolare:510.44Droperidol
CAS:<p>Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.</p>Formula:C22H22FN3O2Purezza:97.16% - 98%Colore e forma:SolidPeso molecolare:379.43Terbutaline
CAS:Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterolFormula:C12H19NO3Purezza:99.12%Colore e forma:SolidPeso molecolare:225.3Quetiapine hemifumarate
CAS:Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.Formula:C46H54N6O8S2Purezza:99.32% - >99.99%Colore e forma:White Crystalline SolidPeso molecolare:883.09Dynarrestin
CAS:Dynarrestin inhibits cytoplasmic dynein 1/2, preventing microtubule sliding without affecting ATP hydrolysis or ciliogenesis.Formula:C22H23F2N3O2SPurezza:99.64%Colore e forma:SolidPeso molecolare:431.5Levocetirizine
CAS:Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist.Formula:C21H25ClN2O3Purezza:98% - 99.94%Colore e forma:White PowderPeso molecolare:388.89Imidazolidinyl urea
CAS:<p>Imidazolidinyl urea (Imidurea) is an antimicrobial preservative used in cosmetics.</p>Formula:C11H16N8O8Purezza:98.6%Colore e forma:White Fluid Powder With Slight Characteristic OdorPeso molecolare:388.29Benztropine mesylate
CAS:<p>Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON</p>Formula:C21H25NO·CH4SO3Purezza:98.41% - 99.96%Colore e forma:White Crystalline Powder; Odourless Or Almost OdourlessPeso molecolare:403.536-Iodopravadoline
CAS:<p>6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.</p>Formula:C23H25IN2O3Purezza:99.29%Colore e forma:Off-White SolidPeso molecolare:504.36DREADD agonist 21
CAS:<p>DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).</p>Formula:C17H18N4Purezza:99.94%Colore e forma:SolidPeso molecolare:278.35Ifenprodil Tartrate
CAS:<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Formula:C21H27NO2C4H6O6Purezza:99.02% - 99.55%Colore e forma:SolidPeso molecolare:400.49Apelin-13
CAS:Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptorFormula:C69H111N23O16SPurezza:96.81%Colore e forma:SolidPeso molecolare:1550.83Pheniramine maleate
CAS:Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formula:C16H20N2·C4H4O4Purezza:99.85%Colore e forma:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CPeso molecolare:356.42Glycerol phenylbutyrate
CAS:Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Formula:C33H38O6Purezza:98.54% - 99.74%Colore e forma:SolidPeso molecolare:530.65Doxepin hydrochloride
CAS:Doxepin hydrochloride, a dibenzoxepin tricyclic, blocks monoamine reuptake and has anticholinergic and antihistaminic effects. Mechanism partly unknown.Formula:C19H22ClNOPurezza:99.65% - 99.91%Colore e forma:White To Off-White PowderPeso molecolare:315.84Ketotifen fumarate
CAS:<p>Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.</p>Formula:C23H23NO5SPurezza:99.25% - 99.73%Colore e forma:SolidPeso molecolare:425.50Ranitidine Hydrochloride
CAS:Ranitidine Hydrochloride (AH19065) is a competitive and reversible inhibitor of histamine H2-receptor antagonists with antacid activity.Formula:C13H23ClN4O3SPurezza:99.30% - 99.49%Colore e forma:SolidPeso molecolare:350.86PF-04995274
CAS:PF-04995274: potent, selective partial 5-HT4R agonist; EC50 0.26-0.47 nM; brain penetrant; may treat Alzheimer's cognitive issues.Formula:C23H32N2O6Purezza:99.52%Colore e forma:SolidPeso molecolare:432.51Dexchlorpheniramine Maleate
CAS:<p>Dexchlorpheniramine Maleate, an antihistamine with anticholinergic effects, treats allergies like hay fever. It's the active isomer of chlorpheniramine.</p>Formula:C20H23ClN2O4Purezza:99.58%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:390.86CI 169369
CAS:<p>CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.</p>Formula:C19H21ClN2SPurezza:98.97%Colore e forma:SoildPeso molecolare:344.9HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Formula:C19H21N3OSPurezza:98.05%Colore e forma:SolidPeso molecolare:339.45DSP-4 hydrochloride
CAS:<p>DSP-4 hydrochloride is a neurotoxin that degrades noradrenergic neurons in rats and crosses the blood-brain barrier.</p>Formula:C11H16BrCl2NPurezza:99.9%Colore e forma:SolidPeso molecolare:313.06Ziprasidone hydrochloride monohydrate
CAS:<p>Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic</p>Formula:C21H21ClN4OS·HCl·H2OPurezza:98% - 99.83%Colore e forma:Off-White PowderPeso molecolare:467.12Heptaminol hydrochloride
CAS:<p>Heptaminol hydrochloride (RP-2831 hydrochloride), a vasoconstrictor, is used in the therapy of hypotension, especially orthostatic hypotension.</p>Formula:C8H20ClNOPurezza:98.61%Colore e forma:White Crystalline PowderPeso molecolare:181.71SBI-477
CAS:<p>SBI-477 deactivates MondoA, inhibits TAG synthesis, and boosts glucose uptake in human muscle cells.</p>Formula:C24H25N3O6SPurezza:99.3%Colore e forma:SolidPeso molecolare:483.54Metaraminol tartrate
CAS:<p>Metaraminol tartrate (Metaradrine tartrate) is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.</p>Formula:C13H19NO8Purezza:99.68%Colore e forma:White PowderPeso molecolare:317.29Clopidogrel hydrogen sulfate
CAS:<p>Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.</p>Formula:C16H16ClNO2S·H2SO4Purezza:99.57% - 99.79%Colore e forma:SolidPeso molecolare:419.9Promethazine
CAS:Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .Formula:C17H20N2SPurezza:99.76%Colore e forma:CrystalsPeso molecolare:284.42CGS 15943
CAS:CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.Formula:C13H8ClN5OPurezza:97.4%Colore e forma:SolidPeso molecolare:285.69Pramipexole
CAS:<p>Pramipexole (SND 919), a dopamine agonist for Parkinson's, may cause mild, temporary enzyme spikes, not acute liver injury.</p>Formula:C10H17N3SPurezza:98% - 99.96%Colore e forma:SolidPeso molecolare:211.33MK-0812 Succinate
CAS:<p>MK-0812 Succinate is an effective and selective CCR2 antagonist.</p>Formula:C28H40F3N3O7Purezza:98.62% - 99.93%Colore e forma:SolidPeso molecolare:587.63Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formula:C21H27ClN2S2Purezza:99.55% - 99.957%Colore e forma:White To Off-White SolidPeso molecolare:407.04Fezolinetant
CAS:<p>Fezolinetant (ESN-364) is a neurokinin-3 receptor antagonist that is being investigated for menopausal hot flashes.Cost-effective and quality-assured.</p>Formula:C16H15FN6OSPurezza:98.62% - 99.7%Colore e forma:SolidPeso molecolare:358.39Pericyazine
CAS:<p>Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist.</p>Formula:C21H23N3OSPurezza:99.61%Colore e forma:SolidPeso molecolare:365.49INCB-9471
CAS:INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.Formula:C30H40F3N5O2Purezza:98.80%Colore e forma:SolidPeso molecolare:559.666Roluperidone
CAS:<p>Roluperidone (CYR-101) is a novel cyclic amide derivative.</p>Formula:C22H23FN2O2Purezza:96.46% - 97.77%Colore e forma:SolidPeso molecolare:366.43AM-8123
CAS:AM-8123: oral APJ agonist, potent, inhibits cAMP, activates Gα, key for cardiovascular research.Formula:C27H33N7O5SPurezza:99.59% - 99.76%Colore e forma:SolidPeso molecolare:567.66CCR2-RA-[R]
CAS:<p>CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).</p>Formula:C18H19ClFNO3Purezza:99.7%Colore e forma:SolidPeso molecolare:351.8Tolamolol
CAS:Tolamolol is a selective β-adrenergic blocker that significantly reduces the degree of exercise-induced inhibition of the S-T segment and can be used in theFormula:C19H24N2O4Purezza:98.59%Colore e forma:SolidPeso molecolare:344.4CYM50308
CAS:<p>CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).</p>Formula:C20H21F2N3O2SPurezza:99.43% - 99.77%Colore e forma:SolidPeso molecolare:405.46Tabernanthalog fumarate
CAS:<p>Tabernanthalog fumarate is a 5-HT2A agonist that promotes neuronal growth and reduces alcohol consumption in mice, producing antidepressant-like effects.</p>Formula:C18H22N2O5Purezza:99.83%Colore e forma:SoildPeso molecolare:346.38[Leu15]-Gastrin I, human
CAS:[Leu15]-Gastrin I, human is a variant of Gastrin I, modulating the binding of cholecystokinin to mucosal membranes.Formula:C98H126N20O31Purezza:98.02% - 98.84%Colore e forma:SolidPeso molecolare:2080.16GTS-21 dihydrochloride
CAS:<p>GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.</p>Formula:C19H20N2O2·2HClPurezza:98.54% - >99.99%Colore e forma:SolidPeso molecolare:381.3Eletriptan hydrobromide
CAS:<p>Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.</p>Formula:C22H27BrN2O2SPurezza:99.69% - 99.85%Colore e forma:Tan SolidPeso molecolare:463.43Cloperastine hydrochloride
CAS:<p>Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.</p>Formula:C20H25Cl2NOPurezza:97.74% - 99.42%Colore e forma:SolidPeso molecolare:366.33RS 15385-198
CAS:RS 15385-198 is a less active isomer of Delequamine. Delequamine is a selective alpha2-adrenergic receptor antagonist.Formula:C18H26N2O3SPurezza:>99.99%Colore e forma:SoildPeso molecolare:350.48Relenopride
CAS:<p>YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.</p>Formula:C24H30ClFN4O4Purezza:98.98% - 99.76%Colore e forma:SoildPeso molecolare:492.97CB1 antagonist 2
CAS:CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.Formula:C17H12Cl3N3OPurezza:99.75%Colore e forma:SolidPeso molecolare:380.66YT 146
CAS:YT 146 is a biochemical.Formula:C18H25N5O4Purezza:98.81% - 99.25%Colore e forma:SolidPeso molecolare:375.42
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