Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.017 prodotti)
- Recettore dell'adenosina(211 prodotti)
- Recettore adrenergico(3.057 prodotti)
- Recettore della bombesina(34 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(159 prodotti)
- CaSR(31 prodotti)
- Recettore dei cannabinoidi(220 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(444 prodotti)
- Recettore dell'endotelina(85 prodotti)
- Recettore GNRH(86 prodotti)
- GPCR19(37 prodotti)
- GRK(34 prodotti)
- GTPase(23 prodotti)
- Recettore del glucagone(197 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(388 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(330 prodotti)
- PAFR(11 prodotti)
- PKA(57 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(48 prodotti)
Mostrare 19 più sottocategorie
Trovati 5838 prodotti per "Proteina G/GPCR".
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8-iso Prostaglandin A2
CAS:8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid.Formula:C20H30O4Colore e forma:SolidPeso molecolare:334.45Methylsolfonyl 25(S)-Δ7-dafachronic acid
Methylsulfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with an IC50 value of 0.41 μM. It exhibits low cytotoxicity in HepG2 cells, with an IC50 value greater than 200 μM. Methylsulfonyl 25(S)-Δ7-dafachronic acid is applicable in the study of parasitic diseases.Formula:C28H45NO4SColore e forma:SolidPeso molecolare:491.30693LCKLSL
CAS:LCKLSL, an N-terminal hexapeptide, inhibits AnxA2 and tPA binding, reduces plasmin, and exhibits anti-angiogenic effects.Formula:C30H57N7O8SColore e forma:SolidPeso molecolare:675.89Pasireotide L-aspartate salt
CAS:Pasireotide L-aspartate, a stable cyclohexapeptide, mimics somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).Formula:C62H73N11O13Purezza:98%Colore e forma:SolidPeso molecolare:1180.33dCNP
dCNP binds to NPR-B/C receptors (NPR-B/C receptor), initiating the cGMP signaling pathway and regulating vascular function. It exhibits anti-hypoxic effects by downregulating hypoxia-related genes such as HIF1α and HIF2α. Additionally, dCNP inhibits tumor stroma induction, demonstrating antifibrotic properties. It also enhances immune response by upregulating CTL, NK cells, and conventional type 1 dendritic cells in tumors.Formula:C141H248N38O36S3Colore e forma:SolidPeso molecolare:3147.91(R)-(+)-Atenolol
CAS:(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.Formula:C14H22N2O3Purezza:98.72%Colore e forma:SolidPeso molecolare:266.34Rubraxanthone
CAS:Rubraxanthone is a PAF inhibitor isolated from Garcinia parvifolia Miq.Formula:C24H26O6Colore e forma:SolidPeso molecolare:410.466RGS2-Galpha-q interaction-IN-1
RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.Formula:C30H30ClN7O3Colore e forma:SolidPeso molecolare:572.06(R)-Zevaquenabant
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.Colore e forma:Odour SolidFroxiprost
CAS:Froxiprost (ONO-995) is an analogue of PGF2α. It promotes thymidine uptake, 1,2-diacylglycerol (1,2-DAG) accumulation, and phosphocholine formation in osteoblast-like MC3T3-E1 cells.Formula:C24H29F3O6Colore e forma:SolidPeso molecolare:470.48Ro 25-1553
CAS:Ro 25-1553 is a 31-amino acid analog of vasoactive intestinal peptide (VIP) that functions as an agonist for the VIP2 receptor (VPAC2 receptor). In guinea pig models, Ro 25-1553 exhibits bronchodilator effects on tracheal smooth muscle contraction induced by neural stimuli or Carbachol.Formula:C160H258N46O46Colore e forma:SolidPeso molecolare:3562.04WS 9326A
CAS:WS 9326A is an antagonist of tachykinin receptor from Streptomyces violaceusniger.Formula:C54H68N8O13Purezza:98%Colore e forma:SolidPeso molecolare:1037.181Beraprost
CAS:Beraprost is a stable prostacyclin analog.Formula:C24H30O5Colore e forma:SolidPeso molecolare:398.49Nolomirole
CAS:Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.Formula:C19H27NO4Colore e forma:SolidPeso molecolare:333.4217-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
CAS:Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.Formula:C26H36F3NO4Colore e forma:SolidPeso molecolare:483.572Amylin, amide, human acetate
Amylin, amide, human acetate, Peptide hormone, inhibits glucagon secretion, delays gastric emptying, regulates glucose homeostasis and metabolism.Formula:C165H261N51O55S2·xC2H4O2Colore e forma:White SolidPeso molecolare:3903.3（free base）Tirzepatide monosodium salt
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.Formula:C225H347N48O68NaPurezza:99.69%Colore e forma:SolidPeso molecolare:4835.51Ref: TM-TP1111L1
nePrezzo su richiesta1mg236,00€5mg620,00€10mg1.018,00€25mg1.521,00€50mg2.088,00€100mg2.817,00€1g7.042,00€PSB-22269
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.Formula:C26H21NO6Colore e forma:SolidPeso molecolare:443.45Δ8-THC methyl ether
CAS:Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.Formula:C22H32O2Colore e forma:SolidPeso molecolare:328.49GR 82334
CAS:Tachykinin NK1 receptor antagonist.Formula:C69H91N15O16Purezza:98%Colore e forma:SolidPeso molecolare:1386.57
