Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.025 prodotti)
- Recettore dell'adenosina(251 prodotti)
- Recettore adrenergico(3.027 prodotti)
- Recettore della bombesina(35 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(158 prodotti)
- CaSR(34 prodotti)
- Recettore dei cannabinoidi(218 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(445 prodotti)
- Recettore dell'endotelina(86 prodotti)
- Recettore GNRH(84 prodotti)
- GPCR19(36 prodotti)
- GRK(33 prodotti)
- GTPase(23 prodotti)
- Recettore del glucagone(195 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(385 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
- PAFR(14 prodotti)
- PKA(60 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 19 più sottocategorie
Trovati 6011 prodotti di "Proteina G/GPCR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
RU-SKI 43
CAS:RU-SKI 43: Potent, selective Hhat inhibitor, IC50 850 nM. Anticancer; potential lung adenocarcinoma treatment. Inhibits Gli-1, Akt, mTOR pathways.Formula:C22H30N2O2SPurezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:386.55SUCNR1-IN-2
CAS:SUCNR1-IN-2 (Statement 35) is an effective SUCNR1 inhibitor for studying neurodegenerative diseases.Formula:C17H13F3N2O6Colore e forma:SolidPeso molecolare:398.29Z1078601926
CAS:Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].Formula:C14H19FN2OColore e forma:SolidPeso molecolare:250.31Isopropyl 5-(Diphenylphosphoryl)pentanoate
CAS:Latanoprost, the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α, serves as a prodrug for the free acid form, a potent FP receptor agonist in the eye. Isopropyl 5-(diphenylphosphoryl)pentanoate may exist as a potential trace impurity in commercial latanoprost preparations.Formula:C20H25O3PColore e forma:SolidPeso molecolare:344.4Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formula:C29H26F3N5O3Purezza:99.452% - 99.78%Colore e forma:SolidPeso molecolare:549.54Ref: TM-T17194
1mg144,00€5mg358,00€1mL*10mM (DMSO)432,00€10mg565,00€25mg880,00€50mg1.161,00€100mg1.594,00€Gestonorone Capronate
CAS:Gestonorone Capronate is a progesterone used in benign prostatic hyperplasia and endometrial cancer studies.Formula:C26H38O4Purezza:99.19%Colore e forma:SolidPeso molecolare:414.58Ref: TM-T13703
1mg138,00€5mg303,00€1mL*10mM (DMSO)343,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€DS-1558
CAS:DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDFFormula:C21H21F3O4Colore e forma:SolidPeso molecolare:394.38Fiduxosin hydrochloride
CAS:Fiduxosin hydrochloride is an alpha 1a-adrenoceptor antagonist that may be useful in the treatment of Benign Prostatic Hyperplasia.Formula:C30H30ClN5O4SColore e forma:SolidPeso molecolare:592.11SKF 81297 hydrobromide
CAS:SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.Formula:C16H17BrClNO2Purezza:99.52%Colore e forma:SolidPeso molecolare:370.67MK 0893
CAS:MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.Formula:C32H27Cl2N3O4Purezza:98.79%Colore e forma:SolidPeso molecolare:588.48Phentolamine Analogue 1
CAS:Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic.Formula:C17H19N3OPurezza:99.96%Colore e forma:SolidPeso molecolare:281.35Ref: TM-T12444
1mg81,00€1mL*10mM (DMSO)163,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€CP 154526 hydrochloride
CAS:CP 154526 hydrochloride is a blood-brain barrier-penetrant, selective CRF1 antagonist (Ki = 2.7 nM), with anxiolytic and antidepressant activities.Formula:C23H33ClN4Purezza:99.94%Colore e forma:SolidPeso molecolare:400.99Ref: TM-T22682
1mg50,00€5mg107,00€1mL*10mM (DMSO)109,00€10mg167,00€25mg369,00€50mg604,00€100mg850,00€Bunazosin Hydrochloride
CAS:Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.Formula:C19H28ClN5O3Purezza:99.12%Colore e forma:SolidPeso molecolare:409.91tetranor-Prostaglandin E1
CAS:Tetranor-Prostaglandin E1 (tetranor-PGE1), a metabolite of PGE1 and PGE2, undergoes formation through β-oxidation.Formula:C16H26O5Colore e forma:SolidPeso molecolare:298.37DORA 42
CAS:DORA 42 is a dual antagonist of the orexin receptor OX1R and OX2R.Formula:C22H24N8OSPurezza:98%Colore e forma:SolidPeso molecolare:448.54AZD2423
CAS:AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM forFormula:C20H29ClFN5O2Purezza:98%Colore e forma:SolidPeso molecolare:425.93ONO-AE3-208 sodium
CAS:ONO-AE3-208 is an EP4 receptor antagonist with a Ki of 1.3 nM, exhibiting less potent activity against EP3, FP, and TP receptors (Ki values of 30, 790, and 2,400 nM, respectively), while showing no effect on other prostanoid receptors. In wild type mice, treatment with ONO-AE3-208, in conjunction with 3% dextran sodium sulfate, results in severe colitis characterized by epithelial loss, crypt damage, and inflammation, thereby mimicking the effects of EP4 deletion. Further, this compound has been utilized to investigate the role of EP4 signaling in various biological contexts, including immune and autoimmune responses, inflammation, and cancer.Formula:C24H20FN2O3NaColore e forma:SolidPeso molecolare:426.42AC-099
CAS:AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM).Formula:C9H8ClF3N4Colore e forma:SolidPeso molecolare:264.64Oleoyl-L-α-lysophosphatidic acid sodium salt
CAS:Oleoyl-L-alpha-lysophosphatidic acid sodium salt is an essential cell membrane biosynthetic metabolite that mediates signal transduction by interacting with GFormula:C21H42NaO7PColore e forma:SoildPeso molecolare:460.524Prostaglandin F1β
CAS:PGF1β, a biochemical compound, functions as a pivotal mediator in inflammatory processes and plays an integral role in uterine contractions. It exhibits significant regulatory effects on platelet aggregation and vasodilation, demonstrating its critical importance in cardiovascular health. Additionally, PGF1β contributes to the regulation of kidney function and electrolyte balance, illustrating its widespread impact across various physiological systems.Formula:C20H36O5Colore e forma:SolidPeso molecolare:356.5
