Recettore degli oppioidi
I recettori degli oppioidi sono un gruppo di recettori accoppiati alle proteine G che mediano gli effetti degli oppioidi endogeni ed esogeni. Questi recettori svolgono un ruolo centrale nella modulazione del dolore, nella regolazione dell'umore e nei comportamenti di dipendenza. Gli agonisti e antagonisti dei recettori degli oppioidi sono ampiamente utilizzati nella gestione del dolore e nel trattamento delle dipendenze, nonché nella ricerca sui disturbi neurologici e psichiatrici. Presso CymitQuimica, offriamo una selezione completa di modulatori dei recettori degli oppioidi di alta qualità per supportare la tua ricerca in neurobiologia, gestione del dolore e terapia delle dipendenze.
Trovati 322 prodotti di "Recettore degli oppioidi"
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LY2940094
CAS:LY2940094 (LY-2940094) decreases ethanol self-administration in animal models.Formula:C22H23ClF2N4O2SPurezza:99.4%Colore e forma:SolidPeso molecolare:480.96CP 866087
CAS:CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.Formula:C24H30N2O3SPurezza:99.22% - 99.74%Colore e forma:SolidPeso molecolare:426.57ZT 52656A hydrochloride
CAS:ZT 52656A is a selective agonist of kappa opioid, and used for the prevention or alleviation of pain in the eye.Formula:C19H26ClF3N2OPurezza:98.78%Colore e forma:SolidPeso molecolare:390.87Meptazinol hydrochloride
CAS:Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.Formula:C15H23NO·HClPurezza:99.75%Colore e forma:White SolidPeso molecolare:269.81Moguisteine
CAS:Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.Formula:C16H21NO5SPurezza:99.98%Colore e forma:SolidPeso molecolare:339.41Trimebutine maleate
CAS:<p>Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects.</p>Formula:C26H33NO9Purezza:99.76% - 99.98%Colore e forma:White SolidPeso molecolare:503.55Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurezza:97.16% - >99.99%Colore e forma:SolidPeso molecolare:248.36Samidorphan HCl
CAS:<p>Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors.</p>Formula:C21H27ClN2O4Purezza:96.79% - 97.85%Colore e forma:SoildPeso molecolare:406.9Alvimopan
CAS:<p>Alvimopan is a potent opioid antagonist targeting gut receptors to reverse opioid effects on motility.</p>Formula:C25H32N2O4Purezza:99.47% - 99.78%Colore e forma:SolidPeso molecolare:424.53Loperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Purezza:99.91% - >99.99%Colore e forma:Crystals Practically Insoluble In WaterPeso molecolare:513.50Apitegromab
CAS:Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases includingPurezza:97.59% (SDS-PAGE); 99.78% (SEC-HPLC) - >95.0% (SDS-PAGE); 99.62% (SEC-HPLC)Colore e forma:LiquidBTRX-335140
CAS:<p>BTRX-335140 (CYM-53093) is a potent and selective orally active κ-opioid receptor (KOR) antagonist with antagonistic activity.Cost-effective and quality-assured.</p>Formula:C25H32FN5O2Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:453.55Sinomenine hydrochloride
CAS:<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Formula:C19H24ClNO4Purezza:99.43%Colore e forma:SolidPeso molecolare:365.851Naltrexone hydrochloride
CAS:<p>Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.</p>Formula:C20H24ClNO4Purezza:98.72% - 99.65%Colore e forma:White Crystalline PowderPeso molecolare:377.862AH 7563
CAS:AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formula:C16H24N2OColore e forma:SolidPeso molecolare:260.38Leumorphin, human
CAS:Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-Formula:C150H224N42O46Purezza:98%Colore e forma:SolidPeso molecolare:3351.64PIPE-3297
PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.Formula:C23H30N2OPeso molecolare:350.23581Deltorphin acetate
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioidFormula:C46H66N10O12S2Purezza:98.93%Colore e forma:SolidPeso molecolare:1015.21Corynantheidine
CAS:Corynantheidine ((-)-Corynantheidine) is a partial agonist of the mu opioid receptor (MOR) and demonstrates MOR-dependent analgesic effects in mice.Formula:C22H28N2O3Colore e forma:SolidPeso molecolare:368.47Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formula:C26H39N3O4Colore e forma:SolidPeso molecolare:457.61DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Formula:C28H36F3N5O8Purezza:98%Colore e forma:SolidPeso molecolare:627.61SB 205607 dihydrobromide
CAS:non-peptide δ1 opioid receptor agonistFormula:C23H24N2OPurezza:98%Colore e forma:SolidPeso molecolare:344.45Fluorphine
CAS:Fluorphine, an analog of Brorphine, binds to the μ-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTPγS binding activity with an EC50 of 75 nM and β-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.Formula:C20H22FN3OColore e forma:SolidPeso molecolare:339.41KOR agonist 5
KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).Formula:C38H38N2O5Colore e forma:SolidPeso molecolare:602.72[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Formula:C65H107N21O15Purezza:99.59%Colore e forma:SoildPeso molecolare:1422.7Enkephalin-met, ala(2)-
CAS:Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.Formula:C28H37N5O7SPeso molecolare:587.69Neuropeptide AF (human) acetate
<p>Neuropeptide AF (human) acetate (Neuropeptide AF (human) acetate (192387-38-5 Free base)) is an anti-opioid neuropeptide, a Neuropeptide AF (human) derivative,</p>Purezza:99.89%Colore e forma:SoildHINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Colore e forma:SolidPeso molecolare:492.49Deltorphin
CAS:Deltorphin (Dermenkephalin) is Isolated from the skin of Phyllomedusa Sauvage. It also has an affinity to the opioid receptor.Formula:C44H62N10O10S2Purezza:98.96%Colore e forma:SolidPeso molecolare:955.15Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Colore e forma:Odour SolidKOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formula:C21H25N3Colore e forma:SolidPeso molecolare:319.44MOR agonist-4
MOR agonist-4 (2d), having an EC50 of 11 nM, is a G protein-biased agonist of the Kappa opioid receptor (KOR). This compound features a triazole-based, electron-withdrawing CF3 group and a bias factor of 38. MOR agonist-4 is utilized for antipruritic and analgesic applications.Akuammicine
CAS:Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.Formula:C20H22N2O2Colore e forma:SolidPeso molecolare:322.408DuP 747 HCl
CAS:DuP 747 HCl is a selective kappa agonist with analgesic activity.DuP 747 consists of two conformations.Formula:C24H29Cl3N2O2Purezza:99.85%Colore e forma:SoildPeso molecolare:483.86β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Formula:C156H249F3N42O46SColore e forma:SolidPeso molecolare:3537.96Frakefamide TFA
Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.Formula:C32H35F4N5O7Colore e forma:SolidPeso molecolare:677.64CJ-15208
CAS:<p>CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).</p>Formula:C34H35N5O4Colore e forma:SolidPeso molecolare:577.67N-terminally acetylated Endomorphin-1
N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.Formula:C36H40N6O6Purezza:98%Colore e forma:SolidPeso molecolare:652.74β-Endorphin (6-31), human
CAS:β-Endorphin is an endogenous opioid neuropeptide and opioid receptor agonist that preferentially binds to μ-opioid receptors.Formula:C131H218N34O40Purezza:98%Colore e forma:SolidPeso molecolare:2909.38Nociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFormula:C31H41N7O9Purezza:98%Colore e forma:SolidPeso molecolare:655.709[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Formula:C61H99FN22O15Purezza:98%Colore e forma:SolidPeso molecolare:1399.6N-Acetyl-α-Endorphin
CAS:N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Formula:C79H122N18O27SPurezza:98%Colore e forma:SolidPeso molecolare:1787.98β-Endorphin (1-27) (human) acetate
<p>β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity.</p>Formula:C141H221N33O42SPurezza:96.52%Colore e forma:SolidPeso molecolare:3082.52Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Formula:C44H59N11O10Purezza:98%Colore e forma:SolidPeso molecolare:901.43Opioid receptor agonist 1
<p>Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.</p>Formula:C32H45N5OColore e forma:SolidPeso molecolare:515.73KOR agonist 3
KOR agonist 3 (Compound 5) is an agonist of the κ opioid receptor (κOR) with an EC50 of 0.88 nM. It also exhibits some activation of μOR, with an EC50 of 720 nM. However, KOR agonist 3 does not activate δOR at concentrations below 1 μM. Its ability to recruit β-Arrestin-2 is lower than that of U50488.Formula:C24H24N2O3Colore e forma:SolidPeso molecolare:388.46α-Neoendorphin (1-8)
CAS:α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin.Formula:C49H70N12O11Purezza:98%Colore e forma:SolidPeso molecolare:1003.15PL-017
CAS:μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.Formula:C29H37N5O5Purezza:98%Colore e forma:SolidPeso molecolare:535.64[D-Ala2]leucine-enkephalin acetate
[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway ofFormula:C31H43N5O9Purezza:98%Colore e forma:SolidPeso molecolare:629.65[(pF)Phe4]Nociceptin(1-13)NH2 acetate
<p>[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31.</p>Formula:C63H103FN22O17Purezza:98.03%Colore e forma:SolidPeso molecolare:1459.63Dynorphin A (1-13) amide
CAS:Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].Formula:C75H127N25O14Peso molecolare:1602.974-Hydroxy-1-(2-phenylethyl)piperidine
CAS:4-Hydroxy-1-(2-phenylethyl)piperidine is a synthetic ligand for muscarinic acetylcholine receptors (mAChR) or non-opioid intracellular sigma-1 receptors (σ1 receptors). It serves as a metabolite of the opioid compounds furanylfentanyl and 4-fluoroisobutyryl fentanyl (FIBF).Formula:C13H19NOColore e forma:SolidPeso molecolare:205.3U-48520
CAS:U-48520 is an agonist of the μ-opioid receptor (μ-opioid receptor) with an EC50 of 1561 nM.Formula:C16H23ClN2OColore e forma:SolidPeso molecolare:294.82(-)-9-Hydroxycorynantheidine
CAS:<p>(-)-9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine) is a demethylated analog of Mitragynine, functioning as a selective and partial agonist for the μ-opioid receptor (μ-opioid receptor). This compound inhibits electrically stimulated twitch contractions in the guinea pig ileum.</p>Formula:C22H28N2O4Colore e forma:SolidPeso molecolare:384.47Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Formula:C26H31N3OPurezza:98%Colore e forma:SolidPeso molecolare:401.54Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formula:C49H75N15O14Purezza:98%Colore e forma:SolidPeso molecolare:1098.2DPDPE
CAS:DPDPE is selective δ-opioid receptor agonist peptide.Formula:C30H39N5O7S2Purezza:98%Colore e forma:SolidPeso molecolare:645.79UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Formula:C82H138N32O21Purezza:98%Colore e forma:SolidPeso molecolare:1908.19Piperidylthiambutene hydrochloride
CAS:Piperidylthiambutene hydrochloride is an opioid compound that exhibits analgesic effects in animal models.Formula:C17H22ClNS2Colore e forma:SolidPeso molecolare:339.95[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Formula:C61H100N22O15Purezza:98%Colore e forma:SolidPeso molecolare:1381.6Acetalin-2
CAS:Acetalin-2, an opioid peptide with the sequence Ac-Arg-Phe-Met-Trp-Met-Arg-NH2, selectively binds to [3 H]DAMGO with a Ki value of 93.3 nM [1].Formula:C44H66N14O7S2Peso molecolare:967.21U-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Formula:C18H25Cl3N2OColore e forma:SolidPeso molecolare:391.76AH 8529
CAS:AH 8529 is an orally active opioid compound with analgesic properties.Formula:C16H23ClN2OColore e forma:SolidPeso molecolare:294.82Gluten Exorphin B5
CAS:Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.Formula:C30H38N6O7Purezza:98%Colore e forma:SolidPeso molecolare:594.66Herkinorin
CAS:Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Formula:C28H30O8Colore e forma:SolidPeso molecolare:494.53Dermorphin
CAS:<p>Dermorphin is agonist of μ-opioid receptor (MOR) agonist.</p>Formula:C40H50N8O10Purezza:98.82%Colore e forma:SolidPeso molecolare:802.87AH 8532
CAS:<p>AH 8532 is an opioid compound with analgesic effects and is effective in inhibiting the quinone-induced writhing response in mice, with an oral ED50 of 16 mg/kg.</p>Formula:C16H23ClN2OColore e forma:SolidPeso molecolare:294.82Dynorphin B (1-13)
CAS:Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formula:C74H115N21O17Purezza:98%Colore e forma:SolidPeso molecolare:1570.84Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Formula:C90H132N26O25Purezza:98%Colore e forma:SolidPeso molecolare:1978.17CTAP
CAS:Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.Formula:C51H69N13O11S2Purezza:98%Colore e forma:White Solid/PowderPeso molecolare:1104.32R-6890
CAS:<p>R-6890 is an opioid compound with analgesic properties.</p>Formula:C21H24ClN3OColore e forma:SolidPeso molecolare:369.89β-Naltrexamine dihydrochloride
CAS:β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Formula:C20H28Cl2N2O3Purezza:95.98%Colore e forma:SoildPeso molecolare:415.35N-Phenethylnoroxymorphone
CAS:N-Phenethylnoroxymorphone is an opioid compound that can enhance morphine-induced analgesia in rats. It is used in the research of neurological disorders.Formula:C24H25NO4Colore e forma:SolidPeso molecolare:391.46CTOP
CAS:Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.Formula:C50H67N11O11S2Purezza:98%Colore e forma:SolidPeso molecolare:1062.28Cebranopadol hemicitrate
CAS:Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.Colore e forma:SolidD-Ala-Gly-Phe-Met-NH2 monoacetate
CAS:D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, serves as a potent agonist for the opiate δ-receptor [1].Formula:C21H33N5O6SPeso molecolare:483.58AP-238
CAS:<p>AP-238 is a novel synthetic opioid (NSO) that acts as an agonist for the μ-opioid receptor (MOR), with an EC50 of 248 nM. Additionally, AP-238 exhibits analgesic properties.</p>Formula:C18H26N2OColore e forma:SolidPeso molecolare:286.41β-Chlornaltrexamine dihydrochloride
CAS:β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is an effective long-term antagonist of opioid receptors. It efficiently blocks the inhibition of dopamine release mediated by κ opioid receptor agonists. This compound is useful in the research of pain perception mechanisms.Formula:C24H34Cl4N2O3Peso molecolare:540.35MT-7716 free base
CAS:MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.Formula:C27H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:440.54LY255582
CAS:<p>LY255582 is a selective centrally active opioid receptor antagonist with high affinity for mu, delta and kappa receptors with Ki of 0.4 nM, 5.2, 2.0 nM,</p>Formula:C22H35NO2Purezza:98%Colore e forma:SolidPeso molecolare:345.52BAM-22P
CAS:Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.Formula:C130H184N38O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2839.22TAN67
CAS:<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formula:C23H26Br2N2OColore e forma:SolidPeso molecolare:506.282Boc-ypgflt(O-tbu)
CAS:Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Formula:C44H64N6O11Colore e forma:SolidPeso molecolare:853.01CTOP acetate
CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist.Formula:C52H71N11O13S2Purezza:99.87%Colore e forma:SoildPeso molecolare:1122.32Trimebutine
CAS:Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioidFormula:C22H29NO5Purezza:99.49% - 99.86%Colore e forma:SolidPeso molecolare:387.47(Rac)-SNC80
CAS:(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Formula:C28H39N3O2Colore e forma:SolidPeso molecolare:449.63Morphiceptin
CAS:Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors.Formula:C28H35N5O5Peso molecolare:521.61UFP-101 acetate
<p>UFP-101 acetate is a selective and competitive antagonist of the NOP receptor (pKi = 10.24) with >3000-fold selectivity over δ, μ, and κ opioid receptors.</p>Formula:C84H142N32O23Purezza:95.92%Colore e forma:SolidPeso molecolare:1968.23Ac-RYYRWK-NH2
CAS:<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formula:C49H69N15O9Purezza:98%Colore e forma:SolidPeso molecolare:1012.17difelikefalin acetate(1024828-77-0 Free base)
CAS:<p>is a ketone and a building block.</p>Formula:C38H57N7O8Purezza:96.94%Colore e forma:SolidPeso molecolare:739.9AT-121 hydrochloride
CAS:<p>AT-121 hydrochloride: dual nociception/mu-opioid agonist, Ki 3.67/16.49 nM, safe, non-addictive pain reliever with analgesic effects.</p>Formula:C24H39ClN4O3SPurezza:97.28% - >99.99%Colore e forma:SolidPeso molecolare:499.11Naldemedine
CAS:Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Formula:C32H34N4O6Colore e forma:SolidPeso molecolare:570.64Dafphedyn
CAS:Dafphedyn (DAFPHEDYN), a potent endorphin 1-13 analog, induces diuresis and analgesia in rats via IV.Formula:C76H124F5N25O14Colore e forma:SolidPeso molecolare:1706.95[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
CAS:Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo.Formula:C61H102N22O14Purezza:98%Colore e forma:SolidPeso molecolare:1367.6K-Opioid receptor agonist-1
CAS:K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.Formula:C22H29Cl2N3O3Peso molecolare:454.39[Arg14,Lys15]Nociceptin
CAS:Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Formula:C82H137N31O22Purezza:98%Colore e forma:SolidPeso molecolare:1909.18Bilaid C
CAS:Bilaid C: Tetrapeptide μ-opioid agonist from Penicillium (Ki=210 nM), inhibits cAMP (77% at 10 μM), induces Kir currents (EC50=4.2 μM).Formula:C28H38N4O6Peso molecolare:526.62[D-Ala2]-Met-Enkephalinamide
CAS:[D-Ala2]-Met-Enkephalinamide: potent opioid, reduces bile flow centrally, analgesic.Formula:C28H38N6O6SPeso molecolare:586.7N-Desmethyl Loperamide
CAS:N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.Formula:C28H31ClN2O2Colore e forma:SolidPeso molecolare:463.01β-Endorphin, equine
CAS:Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.Formula:C154H248N42O44SPurezza:98%Colore e forma:SolidPeso molecolare:3423.94Adrenorphin
CAS:<p>Adrenorphin (Metorphamide)(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).</p>Formula:C44H69N15O9SPurezza:98%Colore e forma:SolidPeso molecolare:984.18MT-7716 hydrochloride
CAS:MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)Formula:C27H29ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:477(S,S)-J-113397
CAS:(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .Formula:C24H37N3O2Colore e forma:SolidPeso molecolare:399.57BPRMU191
CAS:BPRMU191 is a distinct mu-opioid receptor (MOR) modulator with an EC50 of 2.17 μM in FLIPR Ca2+ assays conducted on CHO-K1/MOR/Gα15 cells. Additionally, BPRMU191 interacts with MOR in the presence of naloxone.Formula:C17H14FNO3SPeso molecolare:331.36Valorphin
CAS:Valorphin (Valorphin TFAsalt) has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.Formula:C44H61N9O11Purezza:98%Colore e forma:SolidPeso molecolare:892.01Clocinnamox mesylate
CAS:Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).Formula:C30H33ClN2O7SColore e forma:SolidPeso molecolare:601.11Helianorphin-19
<p>Helianorphin-19: Potent KOR agonist (Ki=25 nM; EC50=45 nM), 200x selective over μ/δ receptors, effective in mouse pain model, non-sedative.</p>Colore e forma:Liquid[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
CAS:'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'Formula:C76H128N24O15Colore e forma:SolidPeso molecolare:1617.98β-Endorphin (rat)
CAS:β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.Formula:C157H254N42O44SColore e forma:SolidPeso molecolare:3466.07Dynorphin B (1-13) (TFA)
Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .Formula:C76H116N21F3O19Colore e forma:SolidPeso molecolare:1684.86β-Endorphin (1-27) (human)
CAS:β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17,Formula:C139H217N33O40SPurezza:98%Colore e forma:SolidPeso molecolare:3022.47Dynorphin B (1-9)
CAS:Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selectiveFormula:C54H78N16O12Purezza:98%Colore e forma:SolidPeso molecolare:1143.3Ac-RYYRWK-NH2 TFA
CAS:Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.Formula:C51H70F3N15O11Colore e forma:SolidPeso molecolare:1126.21SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Formula:C28H39N3O2Purezza:99.65%Colore e forma:SolidPeso molecolare:449.63Nociceptin (1-13), amide
CAS:Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrainFormula:C61H100N22O15Purezza:98%Colore e forma:SolidPeso molecolare:1381.59DALDA TFA
DALDA TFA is a potent, μ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM.Formula:C30H45N9O5·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:611.74 (free base)Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Formula:C44H70N14O9Purezza:98%Colore e forma:SolidPeso molecolare:939.12BPR1M97
CAS:BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency, with Kis values of 1.Formula:C18H18Cl2N2OPurezza:98.78% - 99.95%Colore e forma:SolidPeso molecolare:349.25Orphine
CAS:<p>Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.</p>Formula:C20H23N3OColore e forma:SolidPeso molecolare:321.42CSD-CH2(1,8)-NH2
<p>CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM.</p>Formula:C76H125N25O15S2Purezza:98%Colore e forma:SolidPeso molecolare:1693.09DBPR116
CAS:DBPR116 is a prodrug of BPRMU191 that can penetrate the blood-brain barrier. It significantly enhances the delivery efficiency of drugs targeting the central nervous system. When combined with the antagonist Naltrexone, DBPR116 demonstrates superior safety and analgesic effects compared to morphine in various in vivo pharmacological studies, including thermal pain models, cancer pain models, constipation, sedation, psychological dependence, heart rate, and respiratory frequency. As a strategy for peripheral administration, DBPR116 effectively alleviates pain while reducing adverse effects, showing promise as a safer opioid analgesic.Formula:C19H18FNO3SColore e forma:SolidPeso molecolare:359.42AH 7959
CAS:AH 7959 is an orally active N-substituted cyclohexylmethylbenzamide compound that exhibits analgesic properties. In mice, the ED50 for oral and subcutaneous administration of AH 7959 exceeds 100 mg/kg.Formula:C19H26Cl2N2OColore e forma:SolidPeso molecolare:369.33Biphalin TFA
CAS:<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Formula:C46H56N10O10·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:909.00 (free base)(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioidFormula:C50H81N15O9Colore e forma:SolidPeso molecolare:1036.27[Nphe1]Nociceptin(1-13)NH2 TFA
[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.Formula:C63H101F3N22O17Colore e forma:SolidPeso molecolare:1495.61DPI-287
CAS:DPI-287, a selective delta-opioid receptor (DOP) agonist, has a K\(_i\) value of 0.39 nM and is applicable for pain research [1].Formula:C31H39N3O2Peso molecolare:485.66Nocistatin
CAS:Nocistatin, a neuropeptide, blocks Nociceptin effects and inhibits 5-HT release, acting on an opioid-related receptor.Formula:C32H56N10O12Colore e forma:SolidPeso molecolare:772.85β-Lipotropin (60-65)
CAS:<p>β-Lipotropin (60-65) (β-LPH (60-65)), an opioid agonist, is a significant [1] opioid peptide.</p>Formula:C33H47N9O8SColore e forma:SolidPeso molecolare:729.85ICI 174,864
CAS:<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formula:C38H53N5O7Purezza:98%Colore e forma:White SolidPeso molecolare:691.87[Met5]-Enkephalin, amide
CAS:[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Formula:C27H36N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:572.68BAN ORL 24 dihydrochloride
CAS:BAN ORL 24 dihydrochloride is a highly potent nociceptin/orphan FQ (N/OFQ) receptor (NOP) antagonist that can be used to study neurological diseases.Formula:C27H37Cl2N3O2Purezza:95.03%Colore e forma:SolidPeso molecolare:506.51Loperamide phenyl
CAS:Loperamide phenyl, an impurity detected in Loperamide, is an opioid receptor agonist.Formula:C35H37ClN2O2Colore e forma:SolidPeso molecolare:553.14BMS-986121
CAS:<p>BMS-986121 is a selective positive allosteric modulator (PAM) of the μ opioid receptor with analgesic effects.</p>Formula:C15H9Cl2N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:366.22Porcine dynorphin A(1-13)
CAS:Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.Formula:C75H126N24O15Purezza:98%Colore e forma:SolidPeso molecolare:1603.95Endomorphin 2 TFA
CAS:Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.Formula:C34H38F3N5O7Colore e forma:SolidPeso molecolare:685.69Alvimopan dihydrate (LY246736 dihydrate)
CAS:Alvimopan dihydrate is a potent, oral μ-opioid receptor blocker (IC50 1.7 nM, Ki 0.47 nM) used in postoperative ileus research.Formula:C25H36N2O6Colore e forma:SolidPeso molecolare:460.56[Leu5]-Enkephalin
CAS:<p>[Leu5]-Enkephalin (Leu-enkephalin) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM</p>Formula:C28H37N5O7Purezza:99.87% - 99.88%Colore e forma:SolidPeso molecolare:555.62Asimadoline
CAS:Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany.Formula:C27H30N2O2Colore e forma:SolidPeso molecolare:414.54ADL-5747 (HCl)
CAS:ADL-5747, an opioid delta receptor agonist, is used potentially for the treatment of pain.Formula:C24H29ClN2O3Colore e forma:SolidPeso molecolare:428.95Ac-RYYRIK-NH2 acetate
Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity.Formula:C46H74N14O11Purezza:99.84%Colore e forma:SolidPeso molecolare:999.17Nociceptin (1-13) amide TFA
<p>Nociceptin (1-13), amide: ORL1 receptor agonist, pEC50 7.9 (mouse vas deferens), Ki 0.75 nM (rat forebrain binding).</p>Formula:C63H101F3N22O17Purezza:97.64%Colore e forma:SolidPeso molecolare:1495.61LY2795050
CAS:<p>LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM).</p>Formula:C23H22ClN3O2Purezza:97.77%Colore e forma:SolidPeso molecolare:407.89DAMGO
CAS:<p>DAMGO (DAGO) is an opioid receptor agonist with the ability to affect the locomotive activity in rodents.</p>Formula:C26H35N5O6Purezza:98.83% - 99.92%Colore e forma:SolidPeso molecolare:513.59Adrenorphin 3TFA(88377-68-8(free base))
<p>Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM).</p>Formula:C50H72N15O15SPurezza:>99.99%Colore e forma:SolidPeso molecolare:1326.26[D-Ala2]leucine-enkephalin
CAS:[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.Formula:C29H39N5O7Purezza:98.06%Colore e forma:SolidPeso molecolare:569.65CTAP(TFA) (103429-32-9 free base)
<p>CTAP(TFA) (103429-32-9 free base) is a potent, highly selective, and brain-penetrant antagonist of the μ-opioid receptor with IC50 of 3.5 nM.</p>Formula:C53H70F3N13O13S2Purezza:99.62%Colore e forma:SolidPeso molecolare:1218.33Difelikefalin acetate
CAS:Difelikefalin acetate (CR 845 acetate) is a peripherally restricted kappa opioid receptor agonist.Formula:C38H57N7O8Purezza:99.55%Colore e forma:SolidPeso molecolare:739.9BAM 22P acetate
BAM 22P acetate is a potent opioid agonist.Formula:C132H188N38O33S2Purezza:99.87%Colore e forma:SoildPeso molecolare:2899.27Dynorphin A acetate(80448-90-4 free base)
Dynorphin A acetate is an Endogenous kappa receptor agonist.Formula:C101H159N31O25Purezza:99.69%Colore e forma:SolidPeso molecolare:2207.58(D-Ser2)-Leu-Enkephalin-Thr
(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.Formula:C33H46N6O10Purezza:94.17%Colore e forma:SoildPeso molecolare:686.75Porcine dynorphin A(1-13) acetate
<p>Porcine dynorphin A(1-13) acetate is a potent κ-opioid agonist with antinociceptive properties, increasing [Ca2+]i like NMDA.</p>Formula:C77H130N24O17Purezza:99.14%Colore e forma:SolidPeso molecolare:1664Dynorphin B (1-13) acetate(83335-41-5 free base)
<p>Dynorphin B (1-13) acetate acts as an agonist on opioid κ-receptor.</p>Formula:C76H119N21O19Purezza:99.72%Colore e forma:SolidPeso molecolare:1630.89DPDPE TFA (88373-73-3 free base)
CAS:DPDPE TFA is selective δ-opioid receptor agonist peptide. DPDPE TFA has an analgesic effect and is antinociceptive in vivo.Formula:C32H40F3N5O9S2Purezza:99.39%Colore e forma:SolidPeso molecolare:759.81Gluten Exorphin C
CAS:Gluten exorphin C is an opioid peptide derived from wheat gluten.Formula:C29H45N5O8Purezza:99.39%Colore e forma:SolidPeso molecolare:591.7Methylnaltrexone bromide
CAS:Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists, acts to reverse the side effects of opioid drugs.Formula:C21H26BrNO4Purezza:99.02%Colore e forma:SolidPeso molecolare:436.35Nociceptin
CAS:Nociceptin (Orphanin FQ) is a 17-amino-acid polypeptide that is structurally related to the opioid peptide dynorphin A.Formula:C79H129N27O22Purezza:99.35%Colore e forma:SolidPeso molecolare:1809.04Salvinorin A
CAS:Salvinorin A is a non-nitrogenous κ-opioid selective agonist.Formula:C23H28O8Purezza:99.06%Colore e forma:SolidPeso molecolare:432.46Naloxegol oxalate
CAS:Naloxegol oxalate (NKTR-118) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.Formula:C36H55NO15Purezza:99.67% - >99.99%Colore e forma:SolidPeso molecolare:741.83Nalmefene hydrochloride
CAS:Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS.Formula:C21H26ClNO3Purezza:98% - 99.85%Colore e forma:SolidPeso molecolare:375.89ADL-5859
CAS:ADL-5859 HCl is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for theFormula:C24H28N2O3·HClPurezza:98.78% - 99.11%Colore e forma:SolidPeso molecolare:428.95Alvimopan monohydrate
CAS:Alvimopan monohydrate is a mu-opioid receptor antagonist that intended for the treatment of constipation in patients who take opiates for pain.Formula:C25H34N2O5Purezza:98%Colore e forma:SolidPeso molecolare:442.55Endomorphin 1
CAS:Endomorphin 1 is a high affinity and selective agonist of the μ-opioid receptor and displays reasonable affinities for kappa3 binding sites (Ki: 20~30 nM).Formula:C34H38N6O5Purezza:95.92%Colore e forma:Solid (Solid Powder )Peso molecolare:610.7Asimadoline hydrochloride
CAS:<p>Asimadoline HCl (EMD-61753) is a kappa-opioid receptor agonist for pruritus and IBS treatment.</p>Formula:C27H31ClN2O2Purezza:98.94% - 99.32%Colore e forma:SolidPeso molecolare:451.01DAMGO TFA (78123-71-4(Free base))
<p>DAMGO TFA (78123-71-4(Free base)) is a potent and selective agonist of the Mu-opioid receptor.Cost-effective and quality-assured.</p>Formula:C28H36F3N5O8Purezza:98.67% - 99.76%Colore e forma:SolidPeso molecolare:627.6MCOPPB
CAS:MCOPPB: potent, selective nociceptin receptor agonist, pKi 10.07, minor opioid activity, anxiolytic in animals, non-sedative.Formula:C26H40N4Colore e forma:SolidPeso molecolare:408.62BW-180C
CAS:<p>BW-180C (DADLE) is a prototypical δ-opioid receptor agonist that also displays activity at the μ-opioid receptor. Displays antinociceptive activity in vivo.</p>Formula:C29H39N5O7Purezza:>99.99%Colore e forma:SolidPeso molecolare:569.65GR 89696 free base
CAS:GR 89696 free base is a potent κ2 opioid receptor agonist with a high selectivity, offering potential benefits in pruritus prevention.Formula:C19H25Cl2N3O3Colore e forma:SolidPeso molecolare:414.33N-Desmethylclozapine
CAS:N-Desmethylclozapine: 5-HT2C antagonist (IC50: 7.1 nM), dopamine D4 antagonist, δ-opioid agonist.Formula:C17H17ClN4Purezza:97.25% - 99.83%Colore e forma:Yellow Crystalline SolidPeso molecolare:312.8EST73502 hydrochloride
CAS:EST73502 HCl is an oral dual MOR agonist/σ1R antagonist, BBB-penetrant, Ki: 64 nM (MOR), 118 nM (σ1R), with antinociceptive properties.Formula:C19H27ClF2N2O2Colore e forma:SolidPeso molecolare:388.88BMS986188
CAS:BMS986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.Formula:C30H31BrO4Purezza:98.76%Colore e forma:SolidPeso molecolare:535.47Deltorphin 2
CAS:<p>Deltorphin 2 ([D-Ala2]-Deltorphin II) is an agonist of δ opioid receptor with an IC50 of 1 nM.</p>Formula:C38H54N8O10Purezza:>99.99%Colore e forma:SolidPeso molecolare:782.88Aticaprant
CAS:<p>Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).Cost-effective and quality-assured.</p>Formula:C26H27FN2O2Purezza:99.53% - 99.93%Colore e forma:SolidPeso molecolare:418.5Sec-O-Glucosylhamaudol
CAS:Sec-O-Glucosylhamaudol has anti-inflammatory and strong antinociceptive properties, acting on p38 MAPK and opioid receptors.Formula:C21H26O10Purezza:99.79%Colore e forma:SolidPeso molecolare:438.43BRL 52537 hydrochloride
CAS:BRL 52537 hydrochloride: selective KOR agonist, may protect against ischemic brain injury, used in stroke and heart attack research.Formula:C18H25Cl3N2OPurezza:99.04%Colore e forma:SolidPeso molecolare:391.76Bisacodyl
CAS:Bisacodyl (Fenilaxan) is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation.Formula:C22H19NO4Purezza:99.45% - 99.78%Colore e forma:Smaller Than 50 Microns Predominate White To Off-White Crystalline PowderPeso molecolare:361.39LY2940094 tartrate
CAS:LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism.Formula:C26H29ClF2N4O8SColore e forma:SolidPeso molecolare:631.04MCOPPB triHydrochloride
CAS:<p>MCOPPB triHydrochloride (MCOPPB 3HCl) is a nociceptin receptor agonist.</p>Formula:C26H43Cl3N4Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:518.01Deltorphin I
CAS:Deltorphin I is an agonist of δ-opioid receptor.Formula:C37H52N8O10Purezza:>99.99%Colore e forma:SolidPeso molecolare:768.86AR-M 1000390 hydrochloride
CAS:ARM-390 HCl is a δ-opioid receptor agonist, brain-penetrant, nonpeptidic, prevents hyperalgesia without desensitization. Derived from SNC 80.Formula:C23H29ClN2OPurezza:98.66%Colore e forma:SolidPeso molecolare:384.94Tyr-Gly-Gly-Phe-Met-OH
CAS:<p>Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin), is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.</p>Formula:C27H35N5O7SPurezza:≥95%Colore e forma:White Lyophilised SolidPeso molecolare:573.66Endomorphin 2
CAS:EM-2 reduces sEPSC frequency/amplitude in lamina IX motoneurons; CTOP reverses this. EM-2-IR affects limb muscles via presynaptic/postsynaptic mechanisms.Formula:C32H37N5O5Purezza:99.64%Colore e forma:SolidPeso molecolare:571.67EST73502 HCl
CAS:EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity.Formula:C19H27ClF2N2O2Purezza:99.96%Colore e forma:SolidPeso molecolare:388.88JTC-801
CAS:JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.Formula:C26H25N3O2·HClPurezza:99.27% - 99.59%Colore e forma:SolidPeso molecolare:447.96BMS-986122
CAS:BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1Formula:C16H15BrClNO3S2Purezza:98.42%Colore e forma:SolidPeso molecolare:448.78Dermorphin TFA
CAS:Dermorphin TFA is a new class of opioids-like peptidesFormula:C42H51F3N8O12Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:916.89Nociceptin (1-7) acetate
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor.Formula:C31H41N7O9Purezza:98.92%Colore e forma:SoildPeso molecolare:655.7Corydaline
CAS:<p>Corydaline: an isoquinoline alkaloid that aids digestion, has anti-inflammatory and pain relief properties, and inhibits CYP2C19 and CYP2C9.</p>Formula:C22H27NO4Purezza:98.97% - 99.86%Colore e forma:SolidPeso molecolare:369.45[Leu5]-Enkephalin, amide acetate
[Leu5]-Enkephalin, amide acetate is a δ opioid receptor agonist.Formula:C30H42N6O8Purezza:99.36%Colore e forma:SolidPeso molecolare:614.69Dynorphin A 1-10 acetate(79994-24-4 free base)
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.Formula:C59H95N19O14Purezza:99.88%Colore e forma:SolidPeso molecolare:1294.53Hemorphin-7 acetate(152685-85-3 free base)
Hemorphin-7 acetate is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin.Formula:C51H68N12O13Purezza:99.66%Colore e forma:SolidPeso molecolare:1057.16Ac-RYYRWK-NH2 acetate
Ac-RYYRWK-NH2 acetate is a potent partial agonist of the nociceptin receptor(NOP), which is the endogenous ORL1 receptor agonist.Formula:C51H73N15O11Purezza:98.59%Colore e forma:SolidPeso molecolare:1072.22Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purezza:99.02% - 99.73%Colore e forma:White PowderPeso molecolare:329.39b-Casomorphin (1-3) Acetate
<p>b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.</p>Formula:C25H31N3O7Purezza:98.99%Colore e forma:SolidPeso molecolare:485.53[Met5]-Enkephalin, amide TFA
[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide (TFA)) is a δ opioid receptors agonist as well as putative ζ (zeta) opioid receptors.Formula:C29H37F3N6O8SPurezza:99.81%Colore e forma:SolidPeso molecolare:686.7PZM21
CAS:<p>PZM21 is an effective and selective μ opioid receptor agonist (EC50: 1.8 nM).</p>Formula:C19H27N3O2SPurezza:99.93% - >99.99%Colore e forma:SolidPeso molecolare:361.5N-terminally acetylated Leu-enkephalin
Leu-enkephalin, an endogenous 5-amino acid peptide, activates opioid receptors; its acetylated form exists.Formula:C30H39N5O8Purezza:>99.99%Colore e forma:SolidPeso molecolare:597.66BMS986187
CAS:BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.Formula:C31H34O4Purezza:99.09%Colore e forma:SolidPeso molecolare:470.6Naloxegol (NKTR-118)
CAS:<p>Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1].</p>Formula:C34H53NO11Colore e forma:SolidPeso molecolare:651.78GR103545
CAS:GR103545 is a selective agonist of the κ-opioid receptor, which is a radiotracer that can be used as in vivo imaging.Formula:C23H29Cl2N3O7Purezza:99.75%Colore e forma:SolidPeso molecolare:530.4Orphanin FQ(1-11) acetate(178249-41-7 free base)
<p>Nociceptin peptide fragment (1-11 aa), potent ORL1/KOR-3 agonist (Ki=55 nM), non-opioid, analgesic in mice.</p>Formula:C51H79N15O16Purezza:95.54%Colore e forma:SolidPeso molecolare:1158.26
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