Glicoscienza

<p>Hyaluronate Rhodamine is a molecule that has been modified with a fluorescent dye. Hyaluronate Rhodamine is a complex carbohydrate that has been synthesized using monosaccharides, methylation, glycosylation, and polysaccharide synthesis. It is used in the study of molecular interactions due to its high purity and fluorescence properties.</p>

1,2,3,4,6-Penta-O-acetyl-β-D-mannopyranose is a custom synthesis of an oligosaccharide that is used in the modification of saccharides and complex carbohydrates. It has been used in the synthesis of glycosylations and methylations. This product is a fluorinated monosaccharide with high purity.

<p>L-Arabonic acid-1,4-lactone (LL) is the product of the reaction between L-arabinose and trifluoroacetic acid. LL is an enantiomer of D-arabinose and has a pK a of 6.5, which makes it a weak base. This compound has been shown to be a hydroxyl group donor in human liver and is also used as a chaperone for protein folding.</p>

<p>(1S) -1- [(2S, 3R,4R) -N-Benzyl-3- benzyloxy- 4-hydroxymethyl-1- azetidinyl] -1, 2- ethanediol is a water soluble, white to off-white powder that can be used as a synthetic carbohydrate. It has the CAS number of 112065-78-8 and can be custom synthesized for specific modifications. The purity of this product is high and it is methylated and glycosylated. This product can be used in click chemistry to make other compounds.</p>

<p>Heparin sulfate NS-oligosaccharide NS is a high purity, custom synthesis, sugar-based heparin. Heparin sulfate NS-oligosaccharide NS is designed for use in glycosylation reactions and provides the opportunity to introduce a variety of functional groups including Click modification, fluorination, methylation, and glycosylation. This product contains no animal derived ingredients. Heparin sulfate NS-oligosaccharide NS can be used in a range of applications such as pharmaceuticals, agrochemicals, and food additives.</p>

2-Acetamido-2-deoxy-b-D-glucopyranosyl amine is a synthetic molecule that has shown to be an effective therapeutic agent for the treatment of juvenile idiopathic arthritis. It binds to the surface of cells and activates the immune system by generating antibodies against the disease. This drug has been shown to reduce disease activity in patients with juvenile idiopathic arthritis, as well as improve quality of life. 2-Acetamido-2-deoxy-b-D-glucopyranosyl amine is being developed for use in other autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and psoriasis.

3-Deoxy-D-manno-2-octulosonic acid ammonium is a bioreactor that is used in the delipidation of fatty acids. It is one of the most effective natural compounds for removing lipids, and it has been shown to be effective in reducing the levels of galactose and cholesterol. 3-Deoxy-D-manno-2-octulosonic acid ammonium has also been shown to be an effective antigen that can be used as a marker for various microorganisms, such as typhimurium, enterobacter, and lettuce.

<p>1-Deoxy-4-C-methyl-3,4-isopropylidene-L-erythro-2-pentulose is a custom synthesis of saccharide in nature. It has fluorination and methylation modification. It is a monosaccharide, which can be modified to form an oligosaccharide or polysaccharide. The CAS number for this compound is</p>

(2S, 3S, 4S) -1-Butyl-4- (hydroxymethyl) - N- methyl- 3- (phenylmethoxy) - 2- azetidinecarboxamide is a synthetic compound that can be used for glycosylation reactions. It has the following characteristics: Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination and Saccharide Modification. The CAS registry number for this compound is 109972-04-6. This product is available for custom synthesis and can be ordered with high purity.

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarodecaose is reported to have potential for novel cosmeceuticals.</p>

Allyl 2-O-benzoyl-3-O-benzyl-a-L-rhamnopyranoside is a complex carbohydrate that can be used in the synthesis of saccharides and polysaccharides. It has been modified by methylation, glycosylation, and carbamylation. The CAS number for this product is 940274-21-5.

<p>1,2-O-IIsopropylidene -b- L- idofuranuronic acid g- lactone is a fluorinated monosaccharide that is synthesized from the glycosylation of erythritol and glycerol. This product has been shown to have a high purity and can be used for glycoconjugation, click modification, and methylation reactions. It has a CAS number of 638984-63-7.</p>

This product is custom synthesized. The synthesis of this product was accomplished by modification, fluorination, methylation and monosaccharide synthesis. It is a synthetic oligosaccharide that has been modified with click chemistry. This product is made up of saccharides in a glycosylation configuration. It is a complex carbohydrate that contains sugar units in various configurations. This product has high purity and can be used as an intermediate for the synthesis of other products.

1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is a high purity product custom synthesized for research purposes. It is a sugar that has been modified by the Click modification and fluorination. 1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is an oligosaccharide with a complex carbohydrate structure that can be used in glycosylation reactions. This product is a saccharide with a CAS number of 19126-99-9.

1,3:4,6-Di-O-benzylidene-D-mannitol is a chiral sugar that is synthesized from d-mannitol. It is used for the preparation of polymers with acrylonitrile and phosphine. 1,3:4,6-Di-O-benzylidene-D-mannitol can be obtained by copolymerizing the monomers d-mannitol and acrylonitrile in an enantioselective manner. The yield of this compound depends on the analytical methods used to determine the composition of the polymer. The product is also used as a ligand in metal hydrides and simplifies the synthesis of chiral methyl esters.

<p>1,2,3,4-Tetra-O-benzyl-6-O-tert-butyldimethylsilyl-b-D-galactopyranose is a glycosylation product of 1,2,3,4 tetra O benzyl 6 O tert butyldimethylsilyl b D galactopyranose. It is a member of the class of complex carbohydrates and has a molecular weight of 582. The compound is soluble in methanol and acetone. It has been shown to be effective for methylation, click modification and fluorination reactions as well as other modifications such as polysaccharide synthesis and saccharide modification. This compound is custom synthesized by our company with high purity.</p>

<p>2,4-Dideoxy-2,4-difluoro-D-glucose is a fluorinated glucose analog that has been synthesized to be used as an imaging agent for positron emission tomography (PET) and single photon emission computed tomography (SPECT). It is labeled with fluorine-18 and can be metabolically incorporated into the cellular glycolytic pathway. 2,4-Dideoxy-2,4-difluoro-D-glucose emits positrons that are detected by PET or SPECT cameras. The incorporation of 2,4-dideoxy-2,4-difluoro--D--glucose into the glycolytic pathway allows it to be used as a marker for positron emission tomography.</p>

A uronic acid of galactose

<p>The chemical structure of Astragalus polysaccharide is complex and consists of an α-D-(1,4)-Glc and (1,6)-α-D-Glcp backbone, and a branch point at O-6. The molecular weight is approximately 3.01 × 105 Da from Mongolian Astragalus using low concentration of ethanol for precipitation and gel chromatography for purification. Spectral analysis results of 1H NMR and 13C NMR showed that the polysaccharide backbone has a 1,3-linked β-D-Gal residue and the branched portion has β-Glc, 1,6-linked α-Gal; 1,5-linked β-Xyl; 1,4-linked β-Gal; β-D-Gal, 1,2-linked α-Rha; and 1,2,4-linked α-Rha residues.</p>

<p>2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl isothiocyanate is a custom synthesis that belongs to the group of complex carbohydrates. It is a polysaccharide that can be modified with methylation and glycosylation. 2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl isothiocyanate has been shown to have high purity and CAS number 41135-18-6.</p>

1,4-Dideoxy-1,4-imino-D-arabinitol (1,4DA) is an inhibitor of glycolysis that has potent inhibitory activity against the enzyme phosphofructokinase. It has been shown to decrease cellular ATP levels in rat liver and kidney tissues. 1,4DA also inhibits urine production by inhibiting the conversion of fructose to glucose in the kidney. This compound is a racemic mixture with two enantiomers: R and S. The pharmacokinetics of 1,4DA have been studied in rats and humans using a model system. In rats, 1,4DA was absorbed rapidly and excreted unchanged in the urine. In humans, this drug was well absorbed after oral administration and metabolized mainly by hydrolysis to form 1,4-dideoxyfructose (Fru).

<p>The compound has been shown to be a methylating agent, which is used in the synthesis of saccharides and oligosaccharides. The compound can also be used as a fluorinating reagent. It is an effective synthesis of complex carbohydrates. The compound has been shown to be an excellent protecting group for carbonyl groups. The compound is not very soluble in water, but it is soluble in organic solvents such as DMSO or DMF.</p>

Sodium carboxymethyl dextran is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. Applications that have been described for carboxymethyl dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and carboxymethyl dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.

Intermediate in the synthesis of Decitabine

Methyl 6-O-tert.butyldiphenylsilyl-a-D-galactopyranoside is an organic chemical compound that belongs to the class of sugar derivatives. This substance is a high purity, custom synthesis and can be modified by fluorination, glycosylation, and methylation. The CAS number for this substance is 52793-71-0. Methyl 6-O-tert.butyldiphenylsilyl-a-D-galactopyranoside is an oligosaccharide with a molecular formula of C14H21NO4S and a molecular weight of 299.38 g/mol. It has a monosaccharide sequence of D -Galp1,6(Galp)2,3GlcNAc(Galp)2,4GlcNAc(Galp)2,5GlcNAc(Galp)2

Ezetimibe-D-glucuronide D4 is a deuterated version of the active molecule, ezetimibe. It is a white to off-white crystalline powder with a molecular weight of 592.1 Da and an empirical formula of C31H41NO7F2·C6H8O7. It is soluble in ethanol and water, and insoluble in ether or chloroform.

<p>4-Methoxyphenyl 4-O-(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,6'-dideoxygalactopyranoside is a modification of the natural carbohydrate galactose. The sugar moiety has been methylated and glycosylated with a levulinate ester and then fluorinated. This compound is highly pure and can be synthesized on custom order.</p>

<p>To assess substrate specificity of galactokinase from S. pneumoniae</p>

Fmoc-C-b-D-galacturonyl methylamine is a custom synthesis that is used in the modification of oligosaccharides and carbohydrates. It is also used as a precursor for the synthesis of glycosylated saccharides by methylation, glycosylation, and fluorination. Fmoc-C-b-D-galacturonyl methylamine has been shown to be an excellent starting material for the production of high purity complex carbohydrates.

<p>(2R, 3R, 4R) -3, 4-Dihydroxy-2-(hydroxymethyl)-1-pyrrolidinepropanoic acid is a sugar derivative of Glycosylation. The compound is a custom synthesis that can be modified to meet your requirements. The CAS number is 1207674-35-8. This product has purity of &gt;99% and can be used in the laboratory or as an intermediate in chemical synthesis.</p>

4-(4-(2-(trifluoromethyl)phenyl)-3-(E)-buten-2-one-1-yl)piperidine-2,6-dione is a custom synthesis that can be modified to include fluorination, methylation, and monosaccharide modifications. This molecule has been shown to have click modification and oligosaccharide modifications with saccharides. It is a polysaccharide that is glycosylated with carbohydrate.

<p>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2-O-isopropylidene-D-galactofuranoside is a custom synthesis of a monosaccharide that can be fluorinated, methylated and modified with the click reaction. It is an oligosaccharide that can be saccharified by glycosylation or polysaccharided by glycosylation. It is a carbohydrate that contains a complex carbohydrate.<br>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2--O--isopropylidene--D--galactofuranoside has CAS No.</p>

The family of sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes. The sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a member of the glucosamine family. It is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes.

<p>2,4,6-Tri-O-acetyl-3-O-benzyl-a-D-glucopyranosyl bromide is a custom synthesis made by Modification of the chemical structure of a natural sugar. It is Fluorinated, Methylated and Monosaccharide with Synthetic Click modification and Oligosaccharide. The CAS number for this compound is 34339-69-0. This compound has many uses including being a Carbohydrate that can be used as a Complex carbohydrate for various purposes.</p>

Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).

This beta-cyclodextrin (β-CD) derivative is an azido-functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

2-Acetamido-3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is a glycan that is found in human serum and maternal blood. The wild type strain of 2,3,4,6,7,8 diacetylgalactosaminyltransferase (GnTIII) gene has been shown to be essential for the synthesis of this glycan. This glycan is also found in the carcinoma cell lines HT1080 and SW480. Structural analysis of the glycan has revealed that it contains a hydroxyl group on the C1 position and an acetamido group on the C2 position. Glycans are polymers that play roles in many biological functions such as cell recognition, immune responses, and carbohydrate metabolism. The structure of this glycan was studied using titration calorim

Substrate for xylosyltransferases

<p>Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thioglucopyranoside is an enantiomer that can be synthesized from the commercially available 2,4,6-triacetylphenyl boronic acid. It has been shown to have a positive effect on insulin sensitivity and uptake in plasma glucose in diabetic patients. Phenyl 2,4,6-tri-O-acetyl-3-O-allyl β D thioglucopyranoside also has a safety profile that is similar to other antidiabetic drugs. This drug has been shown to inhibit influenza virus uptake into cells by competitive inhibition of a transporter type.</p>

<p>Epi-inositol, also known as myo-inositol, is a member of the group of molecules known as sugar alcohols. It is a naturally occurring compound that is found in the human body and can be synthesized by the human body from glucose. Epi-inositol has been shown to have a number of biological effects, including inhibition of cell proliferation and energy metabolism in ovarian cancer cells. Epi-inositol has also been used in clinical trials for treatment of mood disorders such as depression.</p>

<p>7-(2-(2-((N-2-Deoxy-acetamido-beta-D-glucopyranosyl)-(N-methyl)-aminooxy)ethoxy)ethoxy)-naphthalene-1,3-disulfonate is a synthetic compound that can be custom synthesized. It has been specifically designed for the modification of complex carbohydrates by click chemistry. The binding site of 7-(2-(2-((N-2-Deoxy-acetamido-beta-D-glucopyranosyl)-(N-methyl)-aminooxy)ethoxy)ethoxy)-naphthalene 1,3 disulfonate is the anomeric carbon of the sugar moiety. This compound has a CAS number of 2365081–65–6 and can be used in many different applications including glycosylation, oligosaccharide synthesis, and methylation.</p>

<p>Dideoxynojirimycin is a potent hydroxamic acid that inhibits glycosidases. It is used to treat metabolic disorders such as glycogen storage diseases. Dideoxynojirimycin has been shown to inhibit the activity of intestinal maltase, an enzyme involved in the digestion of carbohydrates. This drug also inhibits the synthesis of nucleic acids and proteins, which may be due to its ability to bind nucleophilic groups on enzymes and other biological molecules. The kinetic study showed that 1,6-dideoxynojirimycin has a stereoselective effect on mouse splenocytes, inhibiting their proliferation more effectively than 1,6-dideoxy-N-acetylneuraminic acid.</p>

<p>Intermediate in the synthesis of prostaglandins</p>

<p>N-(7-Oxadecyl)deoxynojirimycin is a chaperone protein. It belongs to the group of proteins that are deficient in patients with type 1 glycogen storage disease and can be used to treat this condition. N-(7-Oxadecyl)deoxynojirimycin has been shown to bind to the endoplasmic reticulum, thereby preventing the maturation of certain proteins and their transport into other cellular compartments. This agent also has a protective function in muscle cells by preventing protein degradation due to abnormal folding or misfolding. The long-term effect of N-(7-Oxadecyl)deoxynojirimycin on skeletal muscle is unclear, although it has been found to be beneficial in the short term for patients with type 1 glycogen storage disease.</p>

<p>Raloxifene-4'-D-glucuronide D4 lithium salt is a synthetic glycosylate drug, which belongs to the group of anti-estrogens. Raloxifene-4'-D-glucuronide D4 lithium salt is used for the treatment of postmenopausal osteoporosis and prevention of osteoporotic fractures in women with intact uterus. It has been shown to inhibit bone resorption, increase bone mineral density and reduce the incidence of vertebral fractures in postmenopausal women. Raloxifene-4'-D-glucuronide D4 lithium salt can be synthesized using a click chemistry reaction which involves the addition of an azide to an alkyne followed by copper catalysis and subsequent reduction with sodium borohydride. Synthesis of this compound can be achieved without any purification steps due to its high purity.</p>

2-Azido-((R)-3,5-O-benzylidene)-2,6-dideoxy-L-gluco-hexitol is a modified sugar that is synthesized from the natural sugar D-glucose. It has been fluorinated at the 2 position of the carbon chain to create an azido group. The chemical modification of this sugar allows for its use in a variety of applications, such as click chemistry, Methylation and Polysaccharide synthesis.

Tri-b-GalNAc-6-aminohexanoate is a synthetic ligand designed to target the asialoglycoprotein receptor (ASGPR) on hepatocytes. The three terminal beta-N-acetylgalactosamine (GalNAc) sugars provide an efficient ASGPR binding. It serves as a platform for lysosomal targeting chimera (LYTAC) development, allowing for the creation of chimeras that specifically target unwanted proteins for degradation within hepatocytes. In addition, tri-b-GalNAc-6-aminohexanoate facilitates the delivery of therapeutic cargo, such as RNA or Cas9 complexes, directly to hepatocytes via ASGPR-mediated endocytosis. This approach is promising for gene therapy and RNAi applications in the liver due to the specificity of ASGPR targeting and the versatility of the conjugation moiety.

<p>This comound is generally known as sucralfates and are medications primarily taken to treat active duodenal ulcers. They are also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.</p>

<p>N-acetyl D-glucosamine (GlcNAc) is an aldohexose (2-acetamido-2-deoxyglucose) in which the hydroxyl group at position 2 is replaced by NHAc (Collins, 2006). N-acetyl D-glucosamine forms the exoskeletons of molluscs and insects as the building block of the polysaccharide chitin (Rudrapatnam, 2003). N-acetyl D-glucosamine is a key component of N- and O-linked glycans, present in glycolipids and the glycosaminoglycan hyaluronic acid (Fallacara, 2018). A recent study has suggested that N-acetyl D-glucosamine may have therapeutic potential for COVID-19 as it affects the spike protein-ACE2 receptor interaction during the infection with SARS-CoV-2 virus (Baysal, 2021).</p>

<p>N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).</p>

<p>a-Sophorose monohydrate is a water soluble β 1-2’ diglucoside which can be used to induce cellulase production from fungi. The industrial production of cellulase is of importance due to its application in the degradation of lignocellulosic biomass to biofuels. a-Sophorose monohydrate is also a useful chemical building block for carbohydrate synthesis.</p>

Hyaluronic acid, a polysaccharide with alternating β (1,3) glucuronide and β (1,4) glucosamine residues labelled with 5-amino-fluorescein gives a yellow fibrous product, which is soluble in both water and electrolytes.  Fluorescein-labelled hyaluronic acid can be used as a probe to follow the fate of hyaluronan in vitro and greatly enhances the visualisation of the permeation of substrates through skin and other tissues. Other applications of fluorescein-labelled hyaluronic acid have been reported in cancer research.

<p>Carageenan is a mixture of gelling sulphated galactans extracted from red algae (typically Euchuma cottonii, Euchuma spinosum Mastocarpus stellata and Chondrus crispus). The structure of all carrageenans consists of a strictly alternating masked repeating unit of 1,3 linked α-D-galactose and 1,4 linked β-D-galactose with variable proportions of sulphate. The α-linked galactose residue occurs as α-3-6-anhydro-2-sulphate.<br>The images were kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

Methyl 4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a modification of the sugar, glucopyranose. This modified sugar can be used to produce complex carbohydrates or polysaccharides. It is synthesized by reacting methyl groups with the hydroxyl group at position 6 of glucopyranose and then reacting with an aldehyde group at position 2. Methyl 4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is also known as DMBG for its chemical name. This compound has CAS number 537894 and a molecular weight of 264.24 g/mol. It has a purity of 99% and can be used in various applications such as glycosylation reactions and fluorination reactions.

2-Methoxycarbonylphenyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a fluorinated monosaccharide that can be used as a glycosylation and polysaccharide modification agent. It has been shown to be useful for the synthesis of complex carbohydrates. This product is available in high purity, custom synthesis, and CAS No. 1093406-94-0.

Building block for 3-O-modified glucosylamide-linked glyconconjugates

Eugenol metabolite intermediate

<p>L-Rhamnose diethyl mercaptal is an antiperspirant and deodorant that is used in combination with other ingredients to reduce or eliminate body odor. It is a supplement, often found in combinations with other compounds such as neodymium and radium. This compound works by preventing the formation of sweat from the apocrine glands, which reduces underarm wetness and body odor. L-Rhamnose diethyl mercaptal also has antimicrobial properties that help prevent bacterial growth on the skin surface.</p>

<p>L-Arabinopyranosyl thiosemicarbazide is a carbohydrate that belongs to the group of saccharides. It is a synthetic, fluorinated monosaccharide that has been modified with methyl groups and glycosylation. L-Arabinopyranosyl thiosemicarbazide is used in the synthesis of complex carbohydrates and oligosaccharides. This compound can be custom synthesized according to your specifications. L-Arabinopyranosyl thiosemicarbazide is available at high purity and low price.</p>

<p>Ziyuglycoside II is a steroidal alkaloid that has been shown to have anti-angiogenic properties. It is a natural compound extracted from the Chinese herb ziyuglycoside. This compound has been shown to inhibit the activation of toll-like receptor 4, which plays an important role in inflammation and immunity. Ziyuglycoside II also inhibits the production of reactive oxygen species and autophagy, leading to cell death by apoptosis. This compound has been shown to be effective against bowel disease and epithelial mesenchymal transition (EMT). Ziyuglycoside II has also been shown to have matrix effects on the cells Hl-60, which are related to tumor metastasis.</p>

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

<p>Caffeic acid 3-O-b-D-glucuronide (3BGA) is a phenolic compound that is found in plants. It has been shown to inhibit the growth of viruses, including influenza virus, and chlorogenic acid isomers have been shown to inhibit the growth of bacteria. The highest concentration of 3BGA was found in the heartwood of the plant. Recent pharmacokinetic studies have shown that caffeic acid 3-O-b-D-glucuronide is metabolized by gut bacteria and excreted in human urine.</p>

<p>Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.Molecular weight range 350 - 3500 Da.</p>

The 1-O-acetyl-2,3:5,6-di-O-isopropylidene-D-mannofuranose is a custom synthesis. It is fluorinated at the 6 position and methylated at the 3 position. This modification is done to give it an acetyl group on the 1 carbon and a hydroxyl group on the 2 carbon. The compound has been synthesized by modifying the natural sugar mannose with an acetyl group and a hydroxyl group. The compound has not been modified in any other way as of yet, but it would be possible to add more modifications such as glycosylation or polysaccharide formation.

Please enquire for more information about (2R,2'R,3S,3'S,4R,4'R,5S,5'S)-6,6'-(1,4-Phenylenebis(ethyne-2,1-diyl))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>1,2-O-Isopropylidene-D-mannitol is an alditol that is synthesized by the reaction of 1,2-O-isopropylidene glycerol with sodium sulfide. This product can be further reacted with allylamine to form a thiepane derivative. Thiepane derivatives are polyhydroxylated and have been shown to have antibacterial activity against Staphylococcus aureus, Mycobacterium tuberculosis, and Streptococcus pneumoniae.</p>

<p>Gycosaminoglycan in many organs; joint lubricant and shock absorber</p>

<p>L-Gulono-gamma-lactone is a natural vitamin C metabolite that is synthesized from L-ascorbic acid in the liver. It has been shown to inhibit the oxidase and other enzymes involved in ascorbic acid metabolism, which may be due to its ability to bind to iron. L-Gulono-gamma-lactone also inhibits polymerase chain reactions in rat liver microsomes and inhibits the activities of ascorbic acid and glutathione reductase in rat hepatic tissues. This compound is not active against humans, but it has been shown to have antioxidation properties.</p>

<p>Gum arabic is an exudate gum picked from Acacia trees growing in tropical arid regions (typically Acacia senegal and Acacia laetia). The polysaccharide is branched with a main chain of (1-3) linked β-D-galactopyranosyl units with side chains of (1-3) β-D-galactopyranosyl units joined to it by (1-6) links. The side chains are 2-5 units in length. Both the main chain and the side chains have attached units of α-L-arabinofuranosyl, α-L-rhamnopyranosyl, β-D-glucuronopyranosyl and 4-O-methyl-β-D-glucuronopyranosyl units.</p>

<p>5-O-Benzoyl-1,2,-O-isopropylidene-3-deoxy-3-ethylidene-a-D-xylofuranoside is a custom synthesis that is a modification of the natural product 5-O-(4'-methylbenzoyl)-1,2,-O-(isopropylidene)-3,5'-di--deoxyxylofuranoside. The fluorination and methylation reactions were carried out to produce the desired product. 5--O--Benzoyl--1,2,-O--isopropylidene--3,5'-di--deoxyxylofuranoside is a monosaccharide that is part of an oligosaccharide or polysaccharide. This compound has been synthesized by Click modification and glycosylation with sugar.</p>

<p>4-Methoxyphenyl 3-O-benzyl-β-D-galactopyranoside is a microstructural stabilizer that can be used in the production of thermoelectric materials. It has been shown to inhibit the growth of bacteria and fungi at temperatures as low as −5°C. The compound has also been shown to have neuroprotective effects, which may be due to its ability to stabilize mitochondria and reduce oxidative stress. 4-Methoxyphenyl 3-O-benzyl-β-D-galactopyranoside is an endogenous ligand for unidentified receptors. It also binds to the amyloid protein in Alzheimer's disease, but does not show any significant toxicity in mice and rats.</p>

<p>Cancer-associated carbohydrate antigen</p>

1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-toluoyl-a-D-ribofuranose is a fluorinated sugar molecule. It is a methylated saccharide that has been modified with click chemistry and glycosylation. The modified sugar can be used to synthesize a variety of complex carbohydrates including oligosaccharides and polysaccharides. This product is available in high purity with CAS No. 1884324-99-5.

D-Allono-1,5-lactone is a glycoside that has been custom synthesized. It is a high purity product with a variety of modification options. This compound can be used for the synthesis of sugars, Click modification, fluorination, and glycosylation. D-allono-1,5-lactone has CAS No. 894408-50-5 and is classified as an oligosaccharide or sugar. It can also be methylated or modified to create saccharides or complex carbohydrates.

<p>Ziyuglycoside I is a naturally occurring compound that has been shown to have physiological effects on skin cells. It has been found to bind to collagen and the matrix of skin cells, which may be its mechanism of action. Ziyuglycoside I also has an anti-inflammatory effect, which may be due to its ability to inhibit transcription-polymerase chain reactions (PCR). It has been shown to have antimicrobial activity against some strains of bacteria that are resistant to antibiotics such as erythromycin and tetracycline. Ziyuglycoside I has potential applications in the treatment of infectious diseases and inflammatory skin diseases.</p>

2-O-Acetyl-3,4,6-tri-O-benzyl-a-D-glucopyranosyl trichloroacetimidate is a custom synthesis. It is a modified oligosaccharide with a fluorinated carbon atom in the 2 position of the acetyl group. This chemical has been shown to be effective for click modification and glycosylation reactions. The CAS number for this chemical is 108869-64-3.

1,2,3,4,6-Penta-O-acetyl-b-D-galactopyranose, also known as beta-D-galactose pentaacetate, has high chemical stability and long shelf life. This protected form of galactose is a key building block of any chemical synthesis of galactose-containing oligosaccharides or glycoconjugates. In the presence of Lewis acids it can be used as a glycosyl donor to make simple glycosides. In order to perform more complex galactosylations it can be converted into more reactive donors, such as glycosyl halides or thioglycosides.

<p>(1S) -1- [(2S, 3S,4R) -4-Hydroxymethyl-3- hydroxy- N-methyl-1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that can be used as a glycosylation or methylation agent. It is a white powder with a molecular weight of 342. The purity of this product is &gt; 98%. This product has CAS No. 517862-65-8.</p>

<p>Inhibitor and pharmacological chaperone of lysosomal β-glucosidase (glucosylceramidase). The compound binds to the unstable glucosidase active site during the folding and post-translational processing in Golgi apparatus and endoplasmatic reticulum. It is effective in stabilising the enzyme and preventing accumulation of glucosylceramides in models for Gaucher disease, especially in the ones carrying N370S mutation. In addition, it has antiviral activity against Hepatitis C virus, which is mediated by misfolding of viral glycoproteins in the presence of the inhibitor.</p>

Methyl 2,3,4-tri-O-pivaloyl-6-O-trityl-a-D-galactopyranoside is a sugar with a molecular weight of 576.6 g/mol. The chemical formula for this compound is C36H50O24 and the structural formula is CH2(COOCH2)5(CHO)3(CHOH)4(COOCH2)5. This product can be custom synthesized to order. Methyl 2,3,4-tri-O-pivaloyl-6-O-trityl-a-D galactopyranoside is used in glycosylation reactions as a protecting group for the hydroxyl groups on the carbohydrate chain. It can also be used as a fluorination agent or in Click modification reactions to modify sugars and oligosaccharides. Methyl 2,3,4 tri - O - p

<p>This compound is a glycosylation product of the monosaccharide fucose and the disaccharide 2-O-benzyl-a-L-thiofucopyranoside. It is a custom synthesis that has been modified by fluorination, methylation and click chemistry. This product is available in high purity and with a CAS No. 183051-73-2.</p>

1,5-Anhydro-D-glucitol 6-dihydrogenphosphate is a biochemical analog. It has been shown to have anti-inflammatory effects in rat models of inflammatory bowel disease and metabolic disorders. 1,5-Anhydro-D-glucitol 6-dihydrogenphosphate inhibits the activity of bacterial enzymes that catalyze protein glycosylation. It also blocks the production of inflammatory cytokines and colony stimulating factors. The enzyme inhibition may be due to its ability to inhibit the synthesis of D-glucose from D-galactose by blocking the enzyme DALR (deleted in liver cancer).

<p>Tri-b-GalNAc-6-aminohexanoate TFA is the peracetylated TFA salt from MT184237. It is a synthetic ligand designed to target the asialoglycoprotein receptor (ASGPR) on hepatocytes. The three terminal beta-N-acetylgalactosamine (GalNAc) sugars provide an efficient ASGPR binding. It serves as a platform for lysosomal targeting chimera (LYTAC) development, allowing for the creation of chimeras that specifically target unwanted proteins for degradation within hepatocytes. In addition, tri-b-GalNAc-6-aminohexanoate facilitates the delivery of therapeutic cargo, such as RNA or Cas9 complexes, directly to hepatocytes via ASGPR-mediated endocytosis. This approach is promising for gene therapy and RNAi applications in the liver due to the specificity of ASGPR targeting and the versatility of the conjugation moiety.</p>

<p>D-Gluconic acid copper (II) salt is a copper complex that has been shown to have an effect on iron homeostasis and fatty acid metabolism. The pharmacokinetics of D-gluconic acid copper (II) salt was studied in rats, which showed that the compound is absorbed quickly and eliminated rapidly. D-Gluconic acid copper (II) salt also has a protective effect against bone cancer in mice. The toxicological studies revealed no adverse effects of D-gluconic acid copper (II) salt on the liver or other organs, but it did produce magnesium salt, which can be toxic to humans. It is not known if there are any interactions with benzalkonium chloride.</p>

N- [(3R, 4R, 5R) - 4- Hydroxy- 5- (hydroxymethyl) - 3- pyrrolidinyl] -acetamide is a synthetic compound that is composed of two molecules of acetamide linked to each other by an ester linkage. The acetamide group is attached to the nitrogen atom of the heterocycle. The N-COOH carbonyl group is attached to the oxygen atom of the heterocycle. N-[(3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(pyrrolidin-1-yl)pyrrolidinium]acetamide has not been studied in humans or animals.

<p>3-Deoxy-3-fluoro-1,2:5,6-di-O-isopropylidene-a-D-allofuranose is a modification of the naturally occurring 3,6-anhydro form of D allofuranose. It is an oligosaccharide that is the product of a synthetic process and has been shown to be useful in glycosylation reactions. 3DFIODA can be methylated at its hydroxyl groups and glycosylated with saccharides. It is also fluorinated at C3 and C6 positions. This compound has CAS number 141173-26-8 and molecular weight of 228.</p>

1,2-O-Cyclohexylidene-myo-inositol (CIM) is a fatty acid that has a 6-hydroxyl group. This compound is used in the diagnosis of chemical biology, immunocomplexes and phosphate derivatives. CIM has been shown to bind to iron and form an immunocomplex with it. CIM also binds to phosphate derivatives, which are found in carbohydrate chemistry. The hydroxyl group on CIM can react with chloride ions and form asymmetric synthesis. Growth factors like insulin and other hormones can be synthesized from this compound through the addition of an amine group or phosphate group. CIM also reacts with monoclonal antibodies for use in diagnostic tests for pancreatic lipase.

<p>Non-reducing storage and transport sugar in woody plants; used as a sweetener</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>D-Sedoheptulose 7-phosphate lithium (DSDP) is a substance that is used in the synthesis of ribulose. It provides the carbonyl group for the synthesis of acetyl-CoA and plays an important role in energy metabolism. DSDP has been shown to be effective against streptococcus faecalis, which may be due to its ability to inhibit protein synthesis by binding to ribulose phosphates, thereby preventing the production of ATP. DSDP also inhibits cellular transformation, which may be due to its ability to bind with DNA and block RNA synthesis. In vitro studies have shown that DSDP can inhibit both Streptococcus faecalis and Escherichia coli at concentrations below 10 mM. These effects are likely mediated by enzymatic activities that are involved in bacterial cell physiology.</p>

<p>Short-term marker of glycemic control</p>

L-[1-13C]Fucose is a custom synthesis. It is an oligosaccharide that consists of D-fucose, which is a sugar found in the cell wall of bacteria. L-[1-13C]Fucose has been used as a substrate for methylation reactions and click chemistry modifications to study the binding affinity of various proteins. This compound has also been used in saccharide modification studies and glycosylation reactions.

<p>2,4,7,8,9-Penta-O-acetyl-N-azidoacetyl-b-neuraminic acid methyl ester is a custom synthesis of a monosaccharide. It is modified with fluorine and methyl groups to give it a higher degree of reactivity. This product can be used for the synthesis of oligosaccharides and polysaccharides. 2,4,7,8,9-Penta-O-acetyl-N-azidoacetyl-b-neuraminic acid methyl ester is also used for click modification reactions on saccharide molecules. The CAS number for this product is 1357804-21-7.</p>

<p>Sucrose acetoisobutyrate (SAIB) is an emulsifier and is compatible with a wide variety of polymers, resins, plasticisers, oils and waxes - where it is used in surface coatings. Food applications have been developed for this compound and it has an E number (E444). It is recognized as a safe food additive in cocktail mixers, beer, malt beverages, or wine coolers and is a potential replacement for brominated vegetable oil.</p>

<p>Methyl 4-O-methyl-β-L-arabinopyranoside is an L-arabinose analogue</p>

Charantoside is a natural flavone glycoside that belongs to the group of c-glycosides. It has significant anti-inflammatory activity, inhibiting tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-7 (MMP-7), which are proinflammatory cytokines. Charantoside also has anti-diabetic properties, as it inhibits glucose uptake and stimulates insulin release from pancreatic β cells in vitro. Charantoside is found in plants of the Cucurbitaceae family, such as cucumber and pumpkin. This compound can be detected by fingerprinting techniques and was found to have been present in at least two plant families. Charantoside has been shown to inhibit TNF-α production in vivo studies conducted on mice.

<p>(4S,5R)-4,5-Dihydroxyhexanal is a conjugate of 4-hydroxy-5-oxononanoic acid and phosphite. It is a hybridized molecule that has been synthesized using an asymmetric synthesis. (4S,5R)-4,5-Dihydroxyhexanal can be used as an analog for digitalis. The compound has the ability to activate cardiac glycoside receptors in the heart and increase the force of contraction of cardiac muscle cells. The effective dose for this drug is not yet known, although it has been shown to have cardiotonic steroid properties.</p>

<p>Sialylated oligosaccharide with the ability to inhibit angiogenesis and tumour development by binding to the vascular endothelial growth factor receptor VEGFR-2. Moreover, sialylated N-glycans in intestinal epithelium of chickens were found to carry terminal sialylgalactose, which interacts with influenza viruses during early stages of infection.</p>