Glicoscienza

1-O-Methyl-beta-D-xylopyranoside is a glycoside that consists of a glucose molecule linked to the hydroxyl group of p-hydroxybenzoic acid through an alpha glycosidic bond. It is found in many plants, such as in the leaves of the common bay tree (Laurus nobilis) and in the bark of the cinnamon tree (Cinnamomum verum). 1-O-Methyl-beta-D-xylopyranoside is used as a sweetener and flavoring agent. It is also used in some pharmaceutical drugs, including antiulcer agents and antidiarrheal agents. This compound has been shown to have an effective dose of 5 mg/kg when given orally to humans.

6-Azido-6-deoxy-D-galactose is a mutagenic compound that is used as a carbon source in the synthesis of other compounds. It has been shown to have mutagenicity in TA100 cells and to be active against Staudinger's naphthol. The compound is synthesised by chemoenzymatic methods, which involve the use of alcohols and an acetyl group. 6-Azido-6-deoxy-D-galactose can be used as a mutagenic agent for the production of mutants with desired properties.

<p>Please enquire for more information about a,a-D-Trehalose dihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

2-Amino-2-deoxy-3-O-methyl-D-glucose is a modified sugar that has been synthesized by the methylation of D-glucose. This product is often used as a building block in glycosylation, which is the process of adding sugars to proteins or polysaccharides. The modification of this carbohydrate makes it resistant to hydrolysis and oxidation reactions, making it suitable for use in pharmaceuticals and other applications. 2-Amino-2-deoxy-3-O-methyl-D-glucose can be fluorinated to produce 2-(Fluoro)amino 2 deoxy 3 O methyl D glucose, which has been shown to have antihypertensive effects in rats with high blood pressure. This product can also be modified with click chemistry to produce 2-[(Azidomethyl)amino]-2 deoxy 3 O methyl D glucose, which can be used

<p>Potent and specific inhibitor of α-mannosidase I. It is active against the Golgi isoform (GMI) of the enzyme and blocks carbohydrate branch elongation from immature to complex and hybrid N-glycans. Its anti-viral activity against HIV-1 is characterized by the alteration of N-glycan pattern and shift to high-mannose glycans on viral glycoprotein gp120, resulting in decreased infectivity of newly synthesized virions.</p>

<p>linear a-(1,4) trisaccharide produced from starch by acid or enzyme hydrolysis</p>

<p>D-Glucosaminic acid is a monosaccharide that is found in many glycosaminoglycans. It has been shown to have synergistic effects when combined with malonic acid and hydroxyl group. D-Glucosaminic acid can be used for wastewater treatment, as it is able to form stable complexes with the anionic groups of cell walls. D-Glucosaminic acid also shows antibacterial activity against bacterial strains, including Mycoplasma pneumoniae and Streptococcus pyogenes. The wild-type strain of Escherichia coli is not inhibited by this compound.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

3-Azido-1-O-t-butyldimethylsilyl-2,3,6-trideoxy-b-L-arabinohexopyranose is a modified sugar. It is used as a building block in the synthesis of oligosaccharides and polysaccharides. This product is custom synthesized to customer's specifications and is available in high purity.

<p>1,3,5-Tri-O-benzoyl-2-O-(1H-imidazole-1-sulfonate)-a-D-ribofuranose (TBIR) is a fatty acid that is synthesized by the condensation of 1,3,5-triacetylbenzene with 2,4,6,-trichlorobenzoyl chloride in the presence of triethylamine and sodium methoxide. TBIR has been shown to be suitable for fabricating polyesters and polyamides. TBIR also has the ability to modify membranes. This modification occurs when TBIR reacts with phospholipids in the membrane bilayer by inserting itself into the membrane bilayer. The mesoporous nature of TBIR allows for diffusional transport through its pores as well as an increased surface area for reactions. It also has a large diameter and branched chains that make it suitable for</p>

3,4,6-Tri-O-allyl-D-glucal is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide and Polysaccharide that can be modified by methylation and glycosylation. The product is a Modification of saccharides that has been shown to have Methylation, Glycosylation, Carbohydrate and Click modification. 3,4,6-Tri-O-allyl-D-glucal has CAS No. 434327-45-4 and is available in High purity with Fluorination.

<p>N-Acetyl-D-glucosamine-3-O-sulphate sodium (NADG) is a type of high purity, monosaccharide that is synthesized from D-glucosamine and sulphuric acid. NADG is a synthetic carbohydrate that can be used in the synthesis of complex carbohydrates. It has been modified to contain fluorine atoms at the 3rd and 4th carbon positions. This modification prevents NADG from being hydrolyzed by aminoglycosides such as kanamycin and neomycin, which are used in chemotherapy treatment.</p>

Glucosamine sulfate potassium chloride is a reaction solution that contains glucosamine and hydrochloric acid. It is used in the treatment of osteoarthritis and related diseases, as well as for the prevention of cardiovascular disease. Glucosamine sulfate potassium chloride has been shown to reduce pain and improve the clinical response in patients with osteoarthritis. The synergic effect of glucosamine sulfate potassium chloride may be due to its ability to inhibit the degradation of collagen by hydrochloric acid. This drug also increases the production of glycoside derivatives from glucose, which are important for basic protein synthesis. Glucosamine sulfate potassium chloride can be used as a dietary supplement for infants, who have fatty acid deficiencies.

<p>Maltol is a polyhydric alcohol that is a natural product of plants. Maltol glucoside is an oligomer of maltol that is formed by the glycosylation of maltol with glucose. This compound has been used as a diagnostic agent to detect lymphocyte transformation and bound form in viruses. It has also been shown to inhibit cancer cell growth, which may be due to its ability to interact with complex enzyme systems. Maltol glucoside has been shown to have anti-inflammatory effects in humans, which may be due to its inhibition of inflammatory enzymes such as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX).</p>

Isolated from the products of the acid reversion of D-mannose

<p>Lactobionic acid is produced by oxidation of lactose. It is widely used in the food and in pharmaceutical field, due to its excellent biocompatibility, biodegradability, nontoxicity, chelating, amphiphilic and antioxidant properties.  Lactobionic acid is produced as a white solid powder, freely soluble in water and slightly soluble in anhydrous ethanol and methanol.</p>

Sorbitol hexaacetate is a low-energy compound that has a hydroxyl group and a phenolic acid. It is used as an intermediate in the production of detergents, surfactants, and other industrial chemicals. In addition to this, sorbitol hexaacetate can be used as a radiation shield and an effective dose for radiation therapy. Sorbitol hexaacetate is also used as an ingredient in lipolytic enzymes. It has been shown to inhibit the activity of lipolytic enzymes by forming hydrogen bonds with the enzyme active site. Magnetic resonance spectroscopy studies have revealed that sorbitol hexaacetate has a cavity that can be filled with water molecules, which may explain its ability to act as an optical polarizer.

<p>3-O-Benzyl-4,6-O-benzylidene-a-D-glucopyranose is a custom synthesis of a complex carbohydrate. This product has CAS No. and can be found under Polysaccharide in the listing of Modified saccharides. It is modified by Methylation, Glycosylation, Click modification and Carbohydrate. The product is synthesized using Fluorination and Synthetic methods. It is high purity, with a purity level of 99%.</p>

2,3:4,5-Di-O-isopropylidene-L-arabitol is a modification of an oligosaccharide in which the hydroxyl group at position 4 on the D-ribose moiety has been replaced with an isopropylidene group. The synthesis of 2,3:4,5-Di-O-isopropylidene-L-arabitol can be achieved by methylation and fluorination of L-arabinose. This compound is used in glycosylations and polysaccharide syntheses. 2,3:4,5-Di-O-isopropylidene-L--arabitol is also found as a natural constituent of many plants. 2,3:4,5--Di--O--isopropylidene--L--arabitol is chemically described as α-(1→6)-D--glucop

<p>6-Deoxy-L-allose is a sugar that belongs to the class of carbohydrates. It is synthesized by chemoenzymatic methods and can be used in the synthesis of glycoconjugates. 6-Deoxy-L-allose has been shown to inhibit acid phosphatase, a key enzyme involved in phosphate group metabolism, by competitive inhibition. This synthetic sugar has also been used as an immobilizing agent for enzymes such as glycosidases and phosphatases.</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

2-Azido-2-deoxy-3,4:5,6-bis-O-isopropylidene-D-mannonic acid methyl ester is a synthetic carbohydrate molecule that has been synthesized from 2,2'-azido-2,2'-dideoxyribose. The monosaccharide moiety of the molecule has been fluorinated to create a reactive site for modification with other molecules. This modification can be done by glycosylation or polysaccharide attachment. The azido group on the sugar can be modified with any number of different methyl groups and this is done through a process called Click chemistry. The chemical formula for 2ADDMEM is C8H12N4O8F. The CAS Number for 2ADDMEM is 103510-60-1 and it has an average purity of 99%.

Isomalto oligomers are a custom synthesis of polysaccharide oligosaccharides. These compounds are modified with methylation, glycosylation, and fluorination to create a high purity product that is free of undesirable contaminants. Isomalto oligomers (DP 4-8) are synthesized from sugars and can be used in the modification of saccharide chains during glycosylation reactions. This product also has the ability to produce click chemistry modifications.

Gadolinium is a magnetic, paramagnetic metal that is used to enhance the contrast in magnetic resonance imaging (MRI) and has been shown to be effective in ectopic expression of gene products. Gadolinium-enhanced MRI has been shown to be a more sensitive method for detection of pancreatic cancer cells than CT scans. Gadolinium also binds to monoclonal antibodies and can be detected using immunohistochemical staining. Gadolinium is a prohormone that is converted into its active form by cleavage of the glycosidic bond between carbons 2 and 3 in the 6-phosphate position. The gadolinium ion is chemically neutral, which may account for its lack of toxicity in vivo.

4-Methylphenyl b-D-thioglucopyranoside is a carbohydrate that has been modified by fluorination, methylation, glycosylation, and click modification. It is an oligosaccharide sugar with CAS No. 1152-39-2 and is custom synthesized for high purity. This compound is synthesized from saccharides or from the combination of monosaccharides using glycosylation and click chemistry. 4-Methylphenyl b-D-thioglucopyranoside can be used as a synthetic intermediate in the synthesis of other compounds.

<p>1,6-b-Galactotriose is a glycosylation product of 1,6-galactose. It is a complex carbohydrate that is found in nature and can be used for modification of saccharides, sugar, oligosaccharides, or other monosaccharides. The product is also used as a building block for the synthesis of custom polysaccharides. It can be fluorinated or methylated and click modified to produce a desired saccharide structure.</p>

<p>Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.</p>

Neoandrographolide is a diterpene compound that has been shown to have a significant cytotoxic effect on HL-60 cells. It also shows matrix effects in body formation and chemiluminescence. Neoandrographolide is extracted from the plant Andrographis paniculata, which belongs to the family Acanthaceae. This plant has been used historically as a medical herb in China and India for centuries. The extract of this plant has shown anti-inflammatory properties and can be used to treat infectious diseases such as bowel disease.

<p>A protected mannose amino acid</p>

Resource for the synthesis of 2-azido- and 2-deoxy-L-glucoses and 1,2-epoxides

Ethyl 2-O-benzoyl-4,6-O-benzylidene-β-D-galactopyranoside (E2B) is a fluorinated oligosaccharide that has been synthesized using the Click chemistry. The synthesis proceeds via an oxidative coupling of benzoyl chloride and 4,6-O-benzylidene β-D galactopyranose. The product was purified by crystallization from methanol. E2B is a complex carbohydrate that can be modified to suit your needs. It is used in research as a model for glycosylation and polysaccharides with methylation or sugar modification.

2-Amino-2-deoxy-glucitol is a kinetic inhibitor of the enzyme glycogen phosphorylase, which catalyzes the rate-limiting step in glycogenolysis. It binds to the enzyme and blocks access to the active site by an amide group, thus inhibiting the phosphorylation of glucose residues. This prevents the breakdown of glycogen and leads to increased levels of blood sugar. 2-Amino-2-deoxy-glucitol is used as a treatment for pertussis (whooping cough) and as an adjunct therapy during insulin shock therapy for diabetic ketoacidosis. The drug has also been shown to bind to histidine residues on the enzyme and inhibit its activity.

Drug carrier for cancer therapy & imaging, biocompatible, soluble, biodegradable

N1-b-D-Galactopyranosylamino-guanidine HCl is a synthetic, fluorinated monosaccharide that contains an amino group on the 1' carbon. It has been modified with methyl groups at the C6 and C7 positions to increase its stability and inhibit enzymatic hydrolysis. This product is also a glycosylation agent for complex carbohydrate synthesis.

<p>N-Acetyl-D-lactosamine heptaacetate is a synthetically produced, fluorinated monosaccharide that is used in the production of glycosylations and polysaccharides. N-Acetyl-D-lactosamine heptaacetate can be custom synthesized to meet your needs. This compound is a high purity product.</p>

6-Deoxy-D-lactose is a custom synthesized, complex carbohydrate that is an Oligosaccharide. It is a polysaccharide with a CAS number of 52689-62-0. 6-Deoxy-D-lactose has been modified by methylation and glycosylation and can be used as a Modification of saccharides. 6-Deoxy-D-lactose has been fluorinated and it can be synthesized by Click modification of sugar or high purity. 6-Deoxy-D-lactose is a white, crystalline powder that is soluble in water, ethanol, and acetone.br> 6 Deoxy Lactose (6DL) is an oligosaccharide that consists of one glucose molecule linked to one galactose molecule via alpha 1-->4 glycosidic linkage. The chemical formula for 6DL is C 12 H 22 O 11 . 6DL

(2R,3S,4R)-4-C-((2R,3S)-N-Benzyl-3-tert.butylsilyloxy-2-azetidinyl)-3-O-tert.butyldimethylsilyl-2,3,4-trihydroxybutanoic acid is a methylated and fluorinated oligosaccharide with a high purity. It is a complex carbohydrate that can be modified to include saccharides and monosaccharides. This product is synthesized using Click chemistry and has been shown to have antiallergic activities.

Inulin is a naturally occurring plant carbohydrate that is present in over 36,000 species of plants. Inulin can be found in the roots, tubers, and leaves of various plants. It is used as a food additive and as an ingredient in dietary supplements. Inulin has been shown to have clinical relevance for energy metabolism and fatty acid synthesis. It has also been shown to be effective against inflammatory bowel disease when used as a prebiotic. Isomalt (inositol hexaphosphate) is an artificial sweetener that is often used in sugar-free products such as chewing gum or candy. Anthelmintic drugs are medications that kill worms, which may include nematodes or cestodes. Probiotics are live bacteria that can provide health benefits to humans when consumed in adequate amounts. Acid formation refers to the process by which the stomach produces hydrochloric acid to digest food during digestion. Symptoms of bowel disease include diarrhea and abdominal pain. Water vapor refers to water molecules

Ethyl 6-azido-6-deoxy-a-D-thiomannopyranoside is a custom synthesis of a complex carbohydrate that is used in the modification of saccharides and glycosylations. It can be modified with methylation, fluorination, or click chemistry to create new derivatives. The chemical name for this product is Ethyl 6-azido-6-deoxymannopyranoside. This product has CAS Number 141459-18-4 and molecular weight of 308.86 g/mol. It is available in high purity with 98% yield.

<p>Lewis B tetrasaccharide (LBT) is a glycosylated oligosaccharide that is found in the outer membrane of human pathogens, such as Helicobacter pylori. LBT has been shown to inhibit the growth of cancer cells and may be used as a potential therapeutic agent for cancer treatment. It has also been shown to have structural features similar to those found in inflammatory bowel disease patients, suggesting that it may play a role in regulating bowel inflammation. LBT is recognized by monoclonal antibodies and can be used to detect H. pylori in biological samples. Lewis B tetrasaccharide binds with methyl glycosides on human erythrocytes, which inhibits the polymerase chain reaction (PCR). This inhibition leads to reduced DNA synthesis and a decrease in bacterial replication, making it an effective antimicrobial agent.</p>

Delphinidin 3-galactoside chloride is a natural organic compound that belongs to the flavonol glycosides. It is a pigment that has been identified in flowers and fruits, such as the fruit tree. This compound exhibits antioxidant properties and can scavenge radicals, which may be due to its ability to inhibit dehydroascorbate reductase activity. Delphinidin 3-galactoside chloride also has an effect on high cholesterol levels, which may be due to its ability to inhibit HMG-CoA reductase activity. In addition, it has been shown that this compound can inhibit the growth of human pathogens such as P. aeruginosa and S. aureus.

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

<p>Monofucosyl (1-2)-iso-lacto-N-octaose II is an oligosaccharide that is found in human milk</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>GD3 (shown as sodium salt) has a core disaccharide structure (Galβ1,4Glc) with two sialic acids linked α2,3/α2,8 to the non-reducing galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; it is significantly reduced in adults. However, expression of GD3 is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 was the first cancer-associated ganglioside discovered that promotes adhesion and invasion of cancers. GD3 and GD2 are highly expressed in a various malignant tumours and have become potential targets for next-generation cancer therapy (Liu, 2018).</p>

1,2:4,5-Biscyclohexylidene-DL-myo-inositol is an Oligosaccharide that is synthetically made. It belongs to the group of Glycosylation and can be used in a variety of applications. This compound can be used as a sugar in protein glycosylation, or it can act as an initiator for polysaccharide synthesis. 1,2:4,5-Biscyclohexylidene-DL-myo-inositol has been modified with Click chemistry and has been shown to be high purity and complex carbohydrate.

Gycosaminoglycan in many organs; joint lubricant and shock absorber

Dapagliflozin is an oral antidiabetic drug that acts by inhibiting the SGLT2 enzyme. The SGLT2 enzyme is responsible for reabsorbing glucose from the kidney, so by inhibiting this enzyme, glucose will be excreted in the urine and blood glucose levels will decrease. Dapagliflozin also has a low bioavailability in vivo, which can be improved by administration with food. This drug has been shown to have a longer elimination half-life than canagliflozin and empagliflozin. Dapagliflozin has been shown to have a higher potency than metformin hydrochloride in vitro.

<p>D-Lactal is a dibutyltin oxide that is used in the synthesis of n-acetyllactosamine, disaccharides and trisaccharides. D-Lactal has been shown to have high resistance to chloride ion, which is one of the most common reagents for cleavage. It can also be used as a synthetic precursor for other glycoside derivatives by reacting with triflic acid or trisaccharide. Triflic acid and trisaccharide react with chloride to form a stereoselective glycosidic bond. D-Lactal is also able to bind lectins, carbohydrate chemistry and carbohydrate chemistry reagents.</p>

<p>1,3-O-Benzylidene-D-arabitol is a methylated sugar that is used in the synthesis of complex carbohydrates. It is produced by the modification of a 1,3-O-benzylidene-D-ribitol. It has a CAS number of 70831-50-4 and can be custom synthesized to meet your needs. This product is available in high purity with a 99% yield.</p>