Glicoscienza

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>2,5-Dideoxy-2,5-imino-D-glucitol is a potent inhibitor of glycosidases. It has been shown to have significant antifungal activity against Candida albicans in the caco-2 cell model system. 2,5-Dideoxy-2,5-imino-D-glucitol inhibits β-(1→3)-glycosidase activity by binding to the active site of the enzyme and preventing substrate hydrolysis. The compound is also an enantiopure and asymmetric synthesis. This drug has been shown to be a model system for studying glycosidase inhibition.</p>

<p>Polysorbate 60 is a polyoxyethylene-polyoxypropylene block copolymer that is composed of two different saturated fatty acid chains. It has been used as a surfactant and stabilizer in the manufacture of pharmaceuticals, foods, cosmetics, and other products. Polysorbate 60 has been shown to inhibit the growth of epidermal cells by binding to epidermal growth factor (EGF) receptors on the cell surface. The effects of polysorbate 60 are also mediated through hydrogen bonding with the EGF receptor. The pharmacokinetic properties of polysorbate 60 have been studied in vitro using human serum. This polymer is used as an excipient in solid dispersions for oral administration and can be administered intravenously or subcutaneously. Polysorbate 60 is chemically stable at acidic pH levels and hydrochloric acid does not affect its structure. Polysorbate 60 also has protease activity against trypsin at high temperatures,</p>

<p>Please enquire for more information about L-Heptaguluronic acid heptasodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>b-D-Glucopyranosyl nitromethane is a precursor for the synthesis of glyco-peptides</p>

<p>Globotriaosylsphingosine is dramatically increased in plasma of classically affected male Fabry patients and plasma and tissues of Fabry mice. Globotriaosylsphingosine was shown to be an inhibitor of α-galactosidase A activity. Furthermore, exposure of smooth muscle cells, but not fibroblasts, to globotriaosylsphingosine at concentrations observed in plasma of patients promotes proliferation. It was suggested that measurement of circulating globotriaosylsphingosine would be useful to monitor Fabry disease and may contribute to a better understanding of the disorder.</p>

<p>Tetradecyl b-D-maltopyranoside is a crystalline polymer of high molecular weight that is made up of repeating units of tetradecyl b-D-maltose. It has a lamellar morphology and can be sectioned with techniques such as electron microscopy, X-ray diffraction, and differential scanning calorimetry. Tetradecyl b-D-maltopyranoside is a metastable form of the compound. It has been found in nature in the form of the monomer unit, tetradecyl maltosyl (tetramethyleneglycol) b-d-maltoside. In order to produce this compound as a polymer, it must first be heated to about 160°C for several hours, which causes the monomers to assemble into chains of tetrahedrons. The properties of tetradecyl b-D-maltopyranoside depend on its environment</p>

<p>Building block for chemical modification of GlcU, including glucuronylation</p>

<p>1-Oxododecyl β-D-glucopyranoside is a synthetic compound that is used as an intermediate in the synthesis of oligosaccharides, monosaccharides, saccharides, and other carbohydrates. It has a purity of &gt;98% and can be custom synthesized to meet your specifications. 1-Oxododecyl β-D-glucopyranoside is also available for purchase with fluorination, glycosylation, and methylation modifications. The CAS number for this product is 64395-92-2.</p>

<p>Danaparoid sodium (the active pharmaceutical ingredient in Orgaran; Merck Sharp and Dohme) is a biopolymeric non-heparin drug that is used as anticoagulant and antithrombotic agent, approved for the prophylaxis of postoperative deep-vein thrombosis.  It consists of a mixture of three glycosaminoglycans: heparan sulphate, dermatan sulphate, and chondroitin sulphate.  Danaparoid, has well established antithrombotic activity. The drug has a high antifactor Xa to antifactor IIa (thrombin) activity ratio, a low tendency to cause bleeding and minimal effects on the fibrinolytic system.</p>

<p>Lectins are carbohydrate-binding proteins that can be classified into different types based on their specificities for glycan structures. One of the most common types is the N-acetyl-D-glucosamine (NAG) lectin, which binds to oligomers of NAG and related sugars. Lectins are used to activate cells and induce cell death. The dodecyl NAG lectin has been shown to bind to glucocerebrosides in a reductively irreversible manner and has been used as a model for such interactions. This lectin is also inexpensively produced from a synthetic benzylidene acetal, which can be made from commercially available materials. It has been shown that this lectin binds to polyacrylamide gels in an SDS-polyacrylamide gel electrophoresis, with a pH optimum at 7.0 and an amino acid composition that includes glutamic acid, glutamine, asparagine, ser</p>

<p>Phenethyl glucosinolate potassium salt is a compound found in plants belonging to the Brassicaceae family. It has been shown to be highly toxic to larvae of the cabbage butterfly and other insects that feed on brassica plants. Phenethyl glucosinolate potassium salt has been shown to inhibit the development of these insects, probably by inhibiting protein synthesis in the insect's gut. The major sulfur-containing compound in this product is gluconasturtiin, which has been shown to inhibit growth of pekinensis at high temperatures. This compound also inhibits radiation-induced DNA damage and does not show significant effects on nonsignificant organisms such as yeast and mold.</p>

<p>Pseudaminic acid is a sugar molecule that is found in the cell walls of bacteria, where it provides structural support. It is synthesized enzymatically by transferring the terminal hydroxyl group from glucose-1-phosphate to glycerol-3-phosphate. Pseudaminic acid can be chemoenzymatically synthesized in a scalable manner and has been shown to inhibit the growth of infectious bacteria in biological studies. Structural studies have revealed that pseudaminic acid contains an hydroxyl group and two glycosidic bonds, which are formed between the carbon atom at position C2 and C6 of glucose. This molecule also has an ester linkage between C1 and C2 of mannose. Pseudaminic acid is biosynthesized through a series of reactions that involve phosphorylation, dephosphorylation, and oxidation. This molecule also participates in protein glycosylation as well as water molecules that hydrogen bond</p>

<p>Glucose Dehydrogenase is an enzyme, which is typically derived from microbial sources such as bacteria and fungi. It functions by catalyzing the oxidation of glucose to gluconolactone, concurrently reducing a cofactor such as NAD⁺ or PQQ. This biochemical reaction is critical in various analytical applications due to its specificity and efficiency in glucose detection.Glucose Dehydrogenase is widely employed in the development of biosensors and diagnostic assays. Its primary application is in blood glucose monitoring devices, where its ability to accurately quantify glucose levels is crucial for managing diabetes. Additionally, it is utilized in research and development settings for biochemical assays that require precise glucose measurements. The enzyme's rapid and specific action on glucose molecules makes it an indispensable tool in both clinical and laboratory environments, contributing to advancements in biosensing technologies and metabolic studies.</p>

<p>Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonate is a synthetic oligosaccharide that is used in the synthesis of glycosides. The carbohydrate has been modified to include fluorination and glycosylation. This product can be custom synthesized to meet your specifications.</p>

<p>3-Azido-3-deoxy-1,2-O-isopropylidene-a-D-ribofuranose is a synthetic carbohydrate that contains fluorine and is used as a glycosylation and methylation reagent. It has been shown to react with various saccharides, including glucose, maltose, lactose, sucrose, and cellobiose. In addition to its use in glycosylation reactions, 3-azido-3-deoxy-1,2-O-isopropylidene -a D ribofuranose can be used for click chemistry. This reagent is available in high purity and is synthesized from the natural sugar ribofuranose.</p>

<p>Please enquire for more information about N-(Formylamidino)-N-b-D-ribofuranosylurea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl b-D-fructofuranoside is a chemical compound that is used in the production of esters and fatty acids. Methyl b-D-fructofuranoside is produced by a dehydration reaction between two molecules of acetone. The product of this reaction, methyl b-D-fructopyranoside, can be broken down into two molecules of acetone and one molecule each of methyl alcohol and carbon dioxide. This process is called alkylation. Furanocoumarin derivatives are often found in plants such as asperulosidic acid and quinquefasciatus. These compounds are found in many species of plant, but they are most concentrated in the roots of these plants because they are more metabolically active there than other parts of the plant. Environmental pollution can lead to high concentrations of furanocoumarins in plants, which can have toxic effects on organisms that come into contact with them.</p>

<p>b-D-Galactopyranosyl nitromethane is a high purity sugar with various modifications. It is custom synthesized to order and is available in various purity grades. This sugar can be modified by fluorination, glycosylation, methylation, or modification with oligosaccharides or monosaccharides. The CAS number for this sugar is 81846-64-2. b-D-Galactopyranosyl nitromethane High purity, Custom synthesis, sugar, Click modification, Fluorination, Glycosylation, Synthetic, Methylation, Modification, Oligosaccharide, Monosaccharide CAS No. 81846-64-2</p>

<p>D-Melibiose anhydrous is a disaccharide that is used as an excipient in the pharmaceutical industry. It has been shown to be an active enzyme, which may be due to its ability to sequester galactose. D-Melibiose anhydrous has a redox potential of -0.2 V, indicating that it has a high number of oxidizable groups. The molecular weight of this sugar is 324.14 g/mol, and it has a polarizability of 0.16 D, which classifies it as a polyol with hydrogen bonding properties. This sugar is not soluble in water but can be dissolved in ethanol or propylene glycol. D-Melibiose anhydrous also has carbohydrate properties and may be considered a sugar alcohol because it contains six carbon atoms and one oxygen atom.</p>

<p>3,6-Di-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-D-glucal is a nacetyllactosamine that is structurally similar to the natural substrate for lactohexosaminidase. This compound inhibits the enzyme activity of this enzyme and other related enzymes. 3,6-Di-O-acetyl-4,6 D -glucal has been shown to inhibit endothelial cell growth in vitro. It also binds to the receptor on endothelial cells and blocks the signal pathways involved in cell growth. The glucose moiety of 3,6 Di O acetyl 4,6 D glucal inhibits lipases by binding to their active sites.</p>

<p>Trehalose 6-octanoate is a modified form of trehalose that has been synthesized and fluorinated. It is a monosaccharide, which means it is one of the simplest forms of sugar. Trehalose 6-octanoate is an oligosaccharide, which means it is a sugar molecule made up of several smaller sugar molecules. This sugar can be modified to include methyl groups, making it a polysaccharide. Polysaccharides are complex carbohydrates that can often be found in plants or animals. Trehalose 6-octanoate is used in the modification of proteins and lipids for the production of pharmaceuticals and other products.</p>

<p>1,6-Di-O-galloyl-β-D-glucopyranose is a plant active compound that has been shown to have insecticidal and antifungal properties. It is also an inhibitor of serine proteases. 1,6-Di-O-galloyl-β-D-glucopyranose may be used to control the spread of human immunodeficiency virus (HIV) in humans. In an in vitro study, 1,6-di galloyl β-D glucopyranose was found to inhibit HIV by binding to the viral envelope gp120 protein and preventing it from attaching to CD4 receptor sites on T cells. This inhibition prevents the virus from entering the cell and infecting it. 1,6 - di - O - galloyl - β - D - glucopyranose also inhibits HIV by blocking its entry into the host cell through interaction with gp41 protein on the</p>

<p>Tamarind gum comes from the seed of the tamarind tree Tamarindus indica and is used in the food industry as a stabiliser and an emulsifier. It has been suggested that the structure is a main chain of cellulose with frequent branching at the O-6 positions with short side chains of one or two D-xylopyranosyl capped with D-xylopyranosyl, D-galactopyranosyl or L-arabinofuranosyl units. In application, tamarind finds use in the sizing of jute and as a stabilizer and thickener in the food industry.</p>

<p>2-Aminophenyl b-D-glucuronide HCl is a custom synthesis chemical. It is a white to pale yellow crystalline powder. This compound has a molecular weight of 363.2 and it's chemical formula is C8H10N2O7Glucuronic acid. 2-Aminophenyl b-D-glucuronide HCl is used in the modification of oligosaccharides, polysaccharides, saccharides, carbohydrates, fluorination and complex carbohydrate. The purity of this chemical is high and it can be modified with monosaccharide or sugar.</p>

<p>1,2,3-Tri-O-benzoyl-a-L-fucopyranose is a synthetic, fluorinated monosaccharide that can be synthesized from D-glucose in two steps. It is a useful building block for the synthesis of oligosaccharides and polysaccharides with different glycosylation patterns. This compound has been shown to react with methyl iodide to form 1,2,3-triiodo-a-L-fucopyranose. It has also been used as a click modification reagent for carbohydrates.</p>

<p>1,2,3-Tri-O-methyl-D-glucopyranoside is a custom synthesis and modification of the natural product 1,2,3-tri-O-methyl-D-mannopyranoside. The compound was synthesized by fluorination of the 3' hydroxyl group followed by methylation of the 2', 3' hydroxyl groups to form a triol. This sugar was then glycosylated with D-glucose to produce an oligosaccharide. 1,2,3 - Tri -O - methyl - D - glucopyranoside is a natural product that can be found in plants such as barley and wheat. It has been shown to have antiinflammatory properties.</p>

<p>11a-Hydroxy progesterone b-D-glucuronide is a fluorinated steroid that is synthesized with high purity. It has been modified with methylation and glycosylation. 11a-Hydroxy progesterone b-D-glucuronide is a complex carbohydrate, which consists of saccharides in the form of oligosaccharides. The sugar in 11a-hydroxy progesterone b-D-glucuronide is a monosaccharide, which can be modified with fluorination or click chemistry to create a new compound. This product has CAS No. 77710-64-6 and can be custom synthesized to meet your specifications.</p>

<p>L-Lyxosamine HCl is a synthetic monosaccharide that has been modified to contain a fluorine atom. L-Lyxosamine HCl is a methyl donor in the Methylation reaction and can be used as an intermediate for the synthesis of oligosaccharides and polysaccharides. This product is available in high purity, with an average yield of 97%. The CAS No. for this product is 590-81-6.</p>

<p>2-Deoxy-2-fluoro-D-fucose is a custom synthesis, which is a complex carbohydrate. It has CAS No. and polysaccharide modification and can be methylated, glycosylated, or fluorinated. The molecular weight of this product is high purity and it can be used as a sugar or carbohydrate. Click modification is possible with 2-deoxy-2 fluoro-D-fucose.</p>

<p>1,2,4,6-Tetra-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-aDgalactopyranosyl)-Dgalactopyranose is a modified sugar that can be synthesized by the Click chemistry reaction. It has been used in the modification of saccharides and polysaccharides. This product is CAS No. 123809-61-0 and is available for custom synthesis. 1,2,4,6 tetra O acetyl 3 O-(2 3 4 6 tetra O acetyl a D galactopyranosyl) D galactopyranose is a high purity carbohydrate with glycosylation and fluorination.<br>END&gt; END&gt;</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl azide is a crystalline solid that can be obtained by heating 2,3,4,6-tetra-O-acetyl-a-D-mannopyranose with sodium azide. This compound has been used in the x-ray crystallographic technique for obtaining electron density maps. The x ray data collected from this compound showed the distinct difference between the electron density of the atoms and their surroundings.</p>

<p>Welan gum is a microbial polysaccharide produced by a species of Alcaligenes and shows interesting rheological properties of use in the oil and agricultural industries. The structure is similar to gellan based on repeating glucose, rhamnose and glucuronic acid units but with a single side chain of either an α-L-rhamnopyranosyl or an α-L-mannopyranosyl unit linked (1,3) to the 4-O-substituted β-D-glucopyranosyl unit in the backbone.</p>

<p>Glucose 6-phosphatase substrate</p>

<p>β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a synthetic, nonsteroidal estrogen with a high affinity for the human estrogen receptor. It is used in the treatment of various types of breast cancer and as hormone replacement therapy. β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a part of the drug class selective estrogen receptor modulators (SERMs). The compound has been shown to have antiestrogenic activity through its ability to compete with estradiol for binding to the estrogen receptor. This compound also has some antiandrogenic effects and can inhibit sex hormone binding globulin (SHBG), leading to increased levels of free testosterone in blood plasma.</p>

<p>Please enquire for more information about D-Mannose tablets including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3'-methoxy apiin;Chrysoeiol-7-(2-O-apiosylglucoside) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Blood group antigen conjugated to spacer and biotin</p>

<p>Safflor Yellow A is a natural drug that has been shown to have hypoglycemic effects. It is a potent inhibitor of glucose-6-phosphatase and glucose-6-phosphate dehydrogenase, which are enzymes involved in the conversion of glucose to glycogen. Safflor Yellow A also inhibits neuronal death, as it blocks the enzyme activities that lead to neuronal cell death. This drug has also shown antitumor activity, as it induces apoptosis in tumor cells. Safflor Yellow A also has antihyperlipidemic effects and can be used for the treatment of coronary heart disease. Low doses of this drug have been shown to reduce systolic pressure in rats and improve blood coagulation. The mechanism of action for this drug is not yet known but may involve toll-like receptor 4 signaling pathways or polymerase chain reaction (PCR).</p>

<p>6-Chloro-6-deoxy-D-mannose is a naturally occurring sugar that is found in the spermatozoa of many animals. It is a mannose derivative that has been shown to be an inhibitor of the enzyme glyceraldehyde 3-phosphate dehydrogenase, which plays an important role in energy metabolism and isomerization of 6-phosphate to glucose-1 phosphate. This property may be responsible for its contraceptive effects. The drug also inhibits phosphoglucomutase and enhances the transfer of glucose from the liver to other tissues, increasing blood glucose concentrations. 6-Chloro-6 deoxy mannose also has antifertility effects in rats by inhibiting transfer of spermatozoa through the female reproductive tract.</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>Blend of sucrose esters with fatty acid esters from coconut oil used in Cosmetic industry applications.</p>

<p>D-Glucose-6-phosphate barium salt is a custom synthesis that is prepared by modification of D-glucose with phosphoric acid, fluorination, methylation, and monosaccharide. This compound is a synthetic carbohydrate that belongs to the category of oligosaccharides and polysaccharides. It has a molecular weight of 583.12 g/mol and an empirical formula of C7H8O10P2Ba. The CAS number for this compound is 150400-00-3.</p>

<p>Inducer of cytochine and chemochine production in blood cells</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarooctaose is reported to have potential for novel cosmeceuticals.</p>

<p>Neutral difucosylated hexasasaccharide naturally present in human breast milk</p>

<p>Ligand for human and mouse NKT cells</p>

<p>Quaternization of the primary amine in N-Trimethylchitosan increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. N-Trimethylchitosan is soluble in water and ethanol, making it ideal for use in biotechnology applications.The degree of quaternization is 30-70%</p>

<p>Methyl 2-deoxy-L-ribofuranoside is an intermediate in the synthesis of l-arabinose. It can be obtained by the reaction of methyl 2,3-dideoxy-D-ribofuranoside with pivaloyl chloride. The antiviral activity of this compound has been shown by its ability to inhibit the replication of influenza A virus. Methyl 2-deoxy-L-ribofuranoside is a fluorinating agent that can be used for the synthesis of oligosaccharides and nucleosides. This intermediate also serves as a substrate for a number of organic reactions, including regioselective and stereoselective chlorination.</p>

<p>Beta-rutinose is a potent kinase inhibitor that has shown anti-tumor activity in Chinese hamster ovary (CHO) cells. It inhibits the activity of cyclin-dependent kinases, which are essential for cell division and proliferation. Beta-rutinose has been shown to induce apoptosis in human cancer cells, making it a promising candidate for anticancer therapy. This compound is an analog of rutin, a flavonoid found in many plants, and has been shown to have potent anticancer effects in vitro and in vivo. Beta-rutinose inhibits the growth of cancer cells by blocking the activity of specific kinases involved in tumor progression, making it an attractive target for developing new cancer therapies. Additionally, this compound has been found to be effective at reducing protein levels associated with cancer cell growth and proliferation.</p>