Sistema complementare
Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.
Trovati 165 prodotti di "Sistema complementare"
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Tesidolumab
CAS:Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Purezza:99.72% (SEC-HPLC) - > 95%Colore e forma:LiquidPeso molecolare:142 kDa (average)PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Formula:C47H66N10O8Purezza:99.4%Colore e forma:SolidPeso molecolare:899.09Ref: TM-T12506L1
1mg105,00€5mg266,00€10mg350,00€25mg745,00€50mg1.189,00€100mg1.735,00€1mL*10mM (DMSO)374,00€Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formula:C62H111N11O12Purezza:99.00% - 99.92%Colore e forma:White PowderPeso molecolare:1202.61Ravulizumab
CAS:Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Purezza:> 95%Colore e forma:LiquidPeso molecolare:145.80 kDaDexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purezza:98% - 99.91%Colore e forma:Crystals From Ether (Ntp 1992)Peso molecolare:392.46SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formula:C24H29F3N4O6Purezza:98.93% - 99.89%Colore e forma:SolidPeso molecolare:526.51JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Colore e forma:SolidPeso molecolare:955.08Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Colore e forma:Odour SolidComplement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormula:C22H20F2N6OPurezza:97.77%Colore e forma:SoildPeso molecolare:422.43ATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Formula:C42H62F3N11O11Purezza:98%Colore e forma:SolidPeso molecolare:954TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purezza:98%Colore e forma:SolidPeso molecolare:2432.75Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Colore e forma:SolidPeso molecolare:602.493L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Formula:C38H64N8O13Colore e forma:SolidPeso molecolare:840.9733-O-(2'E,4'Z-Decadienoyl)ingenol
3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.Formula:C30H42O6Colore e forma:SolidPeso molecolare:498.66PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.Formula:C47H63F3N10O8Colore e forma:SolidPeso molecolare:953.06Certepetide
CAS:Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Formula:C37H60N14O14S2Colore e forma:SolidPeso molecolare:989.09PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Colore e forma:SolidAMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formula:C83H117N23O18S2Purezza:98%Colore e forma:SolidPeso molecolare:1789.11ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Colore e forma:SolidPeso molecolare:120702.76PMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Formula:C45H62N10O6Purezza:98%Colore e forma:SolidPeso molecolare:839.04
