H-Phe-Arg-βNA · 2 HCl

CAS: 100929-99-5

Ref. 01-4000885

Product Information

• Name: H-Phe-Arg-βNA · 2 HCl
• Synonyms: MC-207110
• Brand: Bachem
• Description: Substrate for dipeptidyl aminopeptidase I (cathepsin C). A broad-spectrum efflux pump inhibitor in gram-negative bacteria. PAbN has been evaluated as an adjunct to antibiotics, as efflux in bacteria mediates antibiotic resistance. Vecchione et al. demonstrated that Phe-Arg-β-naphthylamide could potentiate drug activity also against a gram-positive bacterium. PAbN permeabilizes the outer membrane of gram-negative bacteria (Lamers et al.).

Chemical properties

• Molecular weight: 519.47
• Formula: C₂₅H₃₀N₆O₂·2HCl
• Purity: > 99%
• Color/Form: White Powder