Estimated delivery in United States, on Monday 3 Apr 2023
Product Information
Name:
α-Synuclein (61-95) (human)
Synonyms:
- Non-Aβ Component of Alzheimer's Disease Amyloid, NAC, Non-β-Amyloid Component of Alzheimer's Disease (NAC)
- Non-A.beta. Component of Alzheimers Disease Amyloid
- H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH
CAS:
Description:
The 35 amino acid peptide NAC (a-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or a-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.
Long term storage:
Notes:
Chemical properties
Molecular weight:
3260.65
Formula:
C141H235N39O49
Purity:
84.7%
Color/Form:
White Powder
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: 01-4026207 α-Synuclein (61-95) (human)
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