5-Fluorouracil, 99%

CAS: 51-21-8

Ref. 02-A13456

Product Information

• Name: 5-Fluorouracil, 99%
• Synonyms: fluorouracil, fluorouracil (inn), 1-fluoropyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-, 2,4-Dihydroxy-5-fluoropyrimidine, 2,4-Dioxo-5-fluoropyrimidine, 5-Fluoracyl, 5-Fluoro Uracil, 5-Fluoro-1H-pyrimidine-2,4-dione, 5-Fluoro-2,4(1H,3H)-pyrimidinedione, 5-Fluoro-2,4-(1H,3H)-pyrimidindion, 5-Fluoro-2,4-Pyrimidinedione, 5-Fluoro-2,4-dihydroxypyrimidine, 5-Fluoropyrimidine-2,4-Dione, 5-Fluoropyrimidine-2,4-diol, 5-Fluoruracil, 5-Fu, 5-Oncouracil, Adrucil, Arumel, Carac, Carzonal, Efudex, Efudix, Efurix, FU, Fluoracil, Fluoroblastin, Fluoroplex, Fluorouracil, Fluorouracil, 5-, Fluorouracile, Fluorouracile Accord, Fluorouracilo, Fluorouracilum, Fluoruracil, Flurablastin, Fluracedyl, Fluracil, Fluracilum, Fluri, Fluril, Ftoruracil, Kecimeton, Nsc 19893, Phthoruracil, Phtoruracil, Queroplex, Ro 2-9757, Sigma 03738, Tegadifure, Timazin, U 8953, Ulup, Uracil, 5-Fluoro-

Description

5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen's disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 130.08
• Formula: C₄H₃FN₂O₂
• Purity: 99%
• Color/Form: Crystalline powder, White to pale cream
• InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
• InChI key: GHASVSINZRGABV-UHFFFAOYSA-N
• SMILES: O=c1[nH]cc(F)c(=O)[nH]1