CAS 51-21-8

5-Fluorouracil

Description:

5-Fluorouracil (5-FU) is a synthetic pyrimidine analog that serves as an antimetabolite in cancer treatment, primarily targeting rapidly dividing cells. Its chemical formula is C4H3FN2O2, and it is characterized by the presence of a fluorine atom at the 5-position of the uracil ring, which alters its metabolic pathways. 5-FU is typically administered intravenously or topically, depending on the type of cancer being treated, such as colorectal, breast, and skin cancers. The mechanism of action involves the inhibition of thymidylate synthase, leading to a depletion of thymidine triphosphate and ultimately disrupting DNA synthesis and repair. 5-Fluorouracil is known for its side effects, which can include gastrointestinal disturbances, myelosuppression, and mucositis, due to its impact on normal rapidly dividing cells. Its efficacy can be enhanced when used in combination with other chemotherapeutic agents. As a potent chemotherapeutic agent, 5-FU remains a critical component in oncological pharmacotherapy.

Formula: C₄H₃FN₂O₂

InChI: InChI=1/C4H3FN2O2/c5-7-2-1-3(8)6-4(7)9/h1-2H,(H,6,8,9)

InChI key: InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N

SMILES: O=C1C(F)=CNC(=O)N1

Synonyms:

• 1-fluoropyrimidine-2,4(1H,3H)-dione
• 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
• 2,4-Dihydroxy-5-fluoropyrimidine
• 2,4-Dioxo-5-fluoropyrimidine
• 5-Fluoracyl
• 5-Fluoro Uracil
• 5-Fluoro-1H-pyrimidine-2,4-dione
• 5-Fluoro-2,4(1H,3H)-pyrimidinedione
• 5-Fluoro-2,4-(1H,3H)-pyrimidindion
• 5-Fluoro-2,4-Pyrimidinedione
• 5-Fluoro-2,4-dihydroxypyrimidine
• 5-Fluoropyrimidine-2,4-Dione
• 5-Fluoropyrimidine-2,4-diol
• 5-Fluoruracil
• 5-Fu
• 5-Oncouracil
• Adrucil
• Arumel
• Carac
• Carzonal
• Efudex
• Efudix
• Efurix
• FU
• Fluoracil
• Fluoroblastin
• Fluoroplex
• Fluorouracil
• Fluorouracil, 5-
• Fluorouracile
• Fluorouracile Accord
• Fluorouracilo
• Fluorouracilum
• Fluoruracil
• Flurablastin
• Fluracedyl
• Fluracil
• Fluracilum
• Fluri
• Fluril
• Ftoruracil
• Kecimeton
• Nsc 19893
• Phthoruracil
• Phtoruracil
• Queroplex
• Ro 2-9757
• Sigma 03738
• Tegadifure
• Timazin
• U 8953
• Ulup
• Uracil, 5-Fluoro-
• 5-faracil
• 3h)-pyrimidinedione,5-fluoro-4(1h
• 5-FLUOROURACIL
• 5-Fluor-2,4-dihydroxypyrimidin
• 1-FLUORO-1H-PYRIMIDINE-2,4-DIONE
• 5-FLUOROPYRIMIDINE-2,4(1H,3H)-DIONE
• 5-fluor-2,4(1h,3h)-pyrimidindion
• [180]-5-Fluorouracil

5-Fluorouracil

CAS: 51-21-8

Formula: C₄H₃FN₂O₂

Purity: >99.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 130.08

Ref: 3B-F0151

5-Fluorouracil, 99%

CAS: 51-21-8

5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses

Formula: C₄H₃FN₂O₂

Purity: 99%

Color and Shape: Crystalline powder, White to pale cream

Molecular weight: 130.08

Ref: 02-A13456

Fluorouracil

CAS: 51-21-8

Fluorouracil

Color and Shape: White

Ref: 47-995

FLUOROURACIL RS

CAS: 51-21-8

FLUOROURACIL RS

Formula: C₄H₃FN₂O₂

Molecular weight: 130.0772

Ref: 41-ICRS0312

FLUOROURACIL CRS

CAS: 51-21-8

FLUOROURACIL CRS

Color and Shape: Added Modified

Ref: 41-F0250000

Fluorouracil

CAS: 51-21-8

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₄H₃FN₂O₂

Color and Shape: White Off-White Powder

Molecular weight: 130.01786

Ref: 45-1279000

5-Fluorouracil

CAS: 51-21-8

5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.

Formula: C₄H₃FN₂O₂

Purity: 98% - >99.99%

Color and Shape: White Solid

Molecular weight: 130.08

Ref: TM-T0984

5-Fluorouracil

CAS: 51-21-8

5-Fluorouracil

Formula: C₄H₃FN₂O₂

Purity: ≥98%

Molecular weight: 130.08

Ref: 54-BUP17413

5-Fluorouracil

CAS: 51-21-8

5-Fluorouracil

Formula: C₄H₃FN₂O₂

Purity: 99%

Color and Shape: White Solid-Powder

Molecular weight: 130.07722

Ref: 54-PC4380

5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS: 51-21-8

Formula: C₄H₃FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 130.0772

Ref: IN-DA003MRU

Fluorouracil-13C-15N2

CAS: 51-21-8

Formula: C₃₁₃CH₃F₁₅N₂O₂

Color and Shape: Pale Yellow Solid

Molecular weight: 133.06

Ref: 4Z-F-532

Fluorouracil

CAS: 51-21-8

Formula: C₄H₃FN₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 130.08

Ref: 4Z-F-536

5-Fluorouracil

CAS: 51-21-8

Formula: C₄H₃FN₂O₂

Purity: ≥ 99.0%

Color and Shape: White to almost white crystalline powder

Molecular weight: 130.08

Ref: 7W-GP6168

5-Fluorouracil-15N2

CAS: 51-21-8, 68941-95-7

Purity: 98 atom % 15N

Color and Shape: White Solid

Molecular weight: 132.10

Ref: 3U-N2140

Fluorouracil

CAS: 51-21-8

Color and Shape: Neat

Ref: 61-FOR0593.00

Fluorouracil

CAS: 51-21-8

Color and Shape: White

Ref: 86-MM0593.00

5-Fluorouracil (Standard)

CAS: 51-21-8

5-Fluorouracil (Standard) is a reference standard for research and analysis in studies involving 5-Fluorouracil. 5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis and autophagy.

Formula: C₄H₃FN₂O₂

Color and Shape: Solid

Molecular weight: 130.08

Ref: TM-TMSM-3471

5-Fluorouracil

Controlled Product

CAS: 51-21-8

Formula: C₄H₃FN₂O₂

Color and Shape: Neat

Molecular weight: 130.08

Ref: 04-C13799500

5-Fluorouracil

CAS: 51-21-8

5-Fluoropyrimidine-2,4(1H,3H)-dione

Formula: C₄H₃FN₂O₂

Purity: 98%

Molecular weight: 130.08

Ref: IN-DG9397

5-Fluorouracil

CAS: 51-21-8

5-Fluorouracil

Formula: C₄H₃FN₂O₂

Purity: 99%

Color and Shape: White Solid-Powder

Molecular weight: 130.07722

Ref: 54-BIF0123