Everolimus

CAS: 159351-69-6

Ref. 02-J60139

Product Information

• Name: Everolimus
• Synonyms: everolimus sdz rad RAD everolimus (substance) certican sdz-rad everolimus (product), (3S,6R,7Z,9R,10R,12R,14S,15E,17Z,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv., 40-O-(2-Hydroxyethyl)rapamycin, 42-O-(2-Hydroxy)ethyl rapamycin, 42-O-(2-Hydroxyethyl)-rapamycin, Afinitor, Afinitor Disperz, Certica, Certican, Certican(R), RAD, Rad-001, Rapamycin, 42-O-(2-hydroxyethyl)-, Sdz-Rad, Sdzrad, Votubia, Xience, Xience V, Zortress

Description

Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 958.24
• Formula: C₅₃H₈₃NO₁₄
• Color/Form: Powder or crystals or crystalline powder or granules or amorphous solid, White to off-white to pale yellow
• InChI key: HKVAMNSJSFKALM-CNPAPGRKSA-N