Neomycin sulfate hydrate

CAS: 1405-10-3

Ref. 02-J61499

Product Information

• Name: Neomycin sulfate hydrate
• Synonyms: 5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-[(3,5-diamino-2-{[3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl)oxy]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol; sulfuric acid, (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (1:1), (2S,3S,4S,5S,6S)-5-amino-2-(aminomethyl)-6-[(1S,2S,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3S,4S,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol,sulfuric acid, Biosol, Bykomycin, Endomixin, Fradiomycin Sulfate, Lidamycin Creme, Myacine, Mycerin sulfate, Mycifradin, Mycifradin N, Mycifradin Sulfate, Myciguent, Neo-Mantle Creme, Neo-rx, Neobrettin, Neofracin, Neolate, Neomix, Neomycin Sulfate, Neomycin, sulfate (salt), Neosulf, New France F, Nivemycin, Nystatin sulfate, O-2,6-Diamino-2,6-Dideoxy-.Beta.-L-Idopyranosyl-(1.->3)-O-.Beta.-D-Ribofuranosyl-(1->5))-O-(2,6-Diamino-2,6-Dideoxy-.Alpha.-D-Glucopyranosyl-(1->4))-2-Deoxy Sulfate, Otobiotic, Quintess-N, Tuttomycin

Description

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 712.72
• Formula: C₂₃H₄₈N₆O₁₇S
• InChI key: OIXVKQDWLFHVGR-DJUBFIBWNA-N