Methotrexate

CAS: 59-05-2

Ref. 02-J63075

Product Information

• Name: Methotrexate
• Synonyms: methotrexate ledertrexate hdmtx arbitrexate methotrexatum 甲氨蝶呤 abitrexate antifolan MTX folex, (+)-4-Amino-10-Methylfolic Acid, (+)-Amethopterin, (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid, 4-Amino-1, 4-Amino-4-Deoxy-N(Sup10, 4-Amino-4-Deoxy-N(Sup10)Methylpteroylglutamic Acid, 4-Amino-N 10-Methylpteroyl-L-Glutamic Acid, 4-Amino-N10-methylfolic acid, 4-Amino-N10-methylpteroylglutamic acid, 4-Amino-N¹⁰-methylfolic acid, 4-Amino-N¹⁰-methylpteroylglutamic acid, <span class="text-smallcaps">L</span>-Amethopterin, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-Methotrexate, Amethopterine, Antifolan, Caditrex, Cl 14377, Emt 25299, Emtexate, Emthexate PF, Emtrexate, Folex, Folex PFS, Folitrax, Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-, Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)-, Jylamvo, L-(+)-Amethopterin, L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-Methotrexate, Ledertrexate, Merex, Metatrexan, Methocel, Methocip, Methotrexat, Methotrexat-Ebewe, Methotrexate LPF, Methoxtrexate, Methylaminopterin, Methylaminopterine, Methylpteroylglutamate, Methylpteroylglutamic Acid, Metorex, Metotrexato, Mexate, Mexate-AQ, Mtx, N-(P-(((2,4-Diamino-6-Pteridinyl)Methyl)Methylamino)Benzoyl)-L-Glutamic Acid, N-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-Glutamic Acid, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, N-[p-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-(+)-glutamic acid, Nordimet, Nsc 740, Oncotrex, R 9985, Remtrex, Rheumatrex, Trexall, Trilem, Zexate

Description

Methotrexate is used as s cell cycle arresting agent that inhibits DHFR. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate is one of the most effective and widely used medications for treating rheumatoid arthritis (RA) and other inflammatory types of arthritis. It is used as an anticancer drug. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 454.45
• Formula: C₂₀H₂₂N₈O₅
• InChI key: FBOZXECLQNJBKD-ZDUSSCGKSA-N