10-300018 - ac-phe-arg-trp-nh2 | 119089-21-3

<p>Ac-Nle-Cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, also known as cycloastragenol, is a synthetic cyclic peptide that inhibits the activity of adipose β3 adrenergic receptors, leading to reduced fat accumulation. Cycloastragenol has been shown to inhibit the formation of atherosclerotic lesions in mice and may have antiatherogenic effects. It also has been shown to inhibit tumor growth in some skin cancer models and has immunosuppressive effects.</p>

<p>Ac-His-D-Phe(p-Iodo)-Arg-Trp-NH2 is a peptide that binds to the melanocortin receptor. It is a potent antagonist of MSH and related peptides and has been shown to be effective in the treatment of cancer, including melanoma.</p>

<p>Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 is a peptide that is a melanocortin receptor agonist. It has been shown to have biochemically active properties and can be used as a research tool in the study of peptides and their receptors.</p>

<p>Ac-Arg-Phe-Met-Trp-Met-Arg-NH2 is a synthetic peptide that binds to the opioid receptors, which are found in many areas of the body, including the brain and peripheral nervous system. Ac-Arg-Phe-Met-Trp-Met-Arg-NH2 has been shown to bind to the mu receptor with an affinity of ˜1 nM. It has also been shown to have antiinflammatory and anticancer properties. Ac-Arg-Phe-Met-Trp-Met -Arg NH2 has also been found in some cases to be effective against neurodegenerative diseases such as Alzheimer's disease. Ac Arg Phe Met Trp Met Arg NH2 is often used as a diluent for peptides and proteins because it does not cause aggregation.</p>

<p>Ac-Arg-Phe-Met-Trp-Met-Lys-NH2 is an opioid receptor agonist with a high affinity for the μ-, δ-, and κ-opioid receptors. Ac-Arg-Phe-Met-Trp-Met-Lys-NH2 binds to these receptors, thereby inhibiting the release of neurotransmitters that transmit pain signals from the peripheral nerves to the brain. Acetyl fentanyl also inhibits the binding of opioid receptor antagonists such as naloxone, which is used in emergency rooms to block or reverse the effects of opioids. Acetyl fentanyl has been shown to be an effective analgesic in animal studies.</p>

<p>Please enquire for more information about Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH2 (Disulfide bond) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ac-Lys-Tyr-Val-Nle-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>HP 228 is a heptapeptide by inhibits the induction of nitric oxide synthase.</p>

<p>Pro-opiomelanocortin (POMC)-derived peptides act on neurons expressing the Melanocortin 4 receptor (MC4R) to reduce body weight. Setmelanotide is a highly potent MC4R agonist that leads to weight loss in diet-induced obese animals and obese individuals with complete POMC deficiency.The endogenous ligand alpha-melanocyte-stimulating hormone (alpha-MSH) for MC4R has been shown to have a much lower affinity than Setmelanotide, explaining some of the drug's potency. Administration of Setmelanotide to wildtype mice resulted in significant weight loss while  MC4R knockout mice fail to respond. Setmelanotide is in numerous clinical trials and shows promising results. Patients with POMC defects upstream of MC4R show more significant responses to treatment than those with MC4R deficiency or obese controls.</p>

<p>Alpha-melanocyte stimulating hormone (alpha-MSH) is a melanocortin family neuropeptide which plays important roles in metabolic and immune homeostasis. It is formed from the cleavage of adrenocorticotropic hormone, the cleavage product of proopiomelanocortin hormone. alpha-MSH is expressed ubiquitously to varying degrees in a wide variety of cells including the hypothalamus, monocytes and retinal pigment epithelial cells. alpha-MSH is a non-selective agonist of melanocortin receptors.alpha-MSH is a suppresser of inflammation from both innate and adaptive immune pathways, it is involved in hair and skin pigmentation (through MC1 receptor activation), has reproductive functions, cardio protective functions and regulates food intake and energy metabolism.The phenylalanine residue at position 7 of this peptide is isotopically labelled with carbon-13 (9) and nitrogen-15 (1), giving this peptide a mass increase of 10 compared to the unlabelled peptide. The N-terminal of the peptide is protected by an acetyl group.</p>

<p>Oligopeptide P11-8 is a reagent that is used as a reaction component. This oligopeptide has been shown to have high purity and quality, making it useful for research purposes. It can be used in the synthesis of peptides and proteins, as well as being a versatile building block for the synthesis of complex compounds. The chemical structure of Oligopeptide P11-8 includes an amino acid sequence that has not been found in nature, which makes it a valuable scaffold for the production of speciality chemicals.</p>

<p>Peptide Ac-QQRFEWEFEQQ-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Melanocyte Stimulating Hormone (MSH) and Related Peptides are a group of peptides that have a role in the regulation of skin pigmentation. One such peptide is Nle4, D-Phe7]-ß-MSH-amide, which is an agonist of melanocortin receptors. It has been shown to stimulate the proliferation and cause the differentiation of melanocytes in vitro, as well as to increase the number of melanocytes in vivo.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Afamelanotide acetate is a human protein that acts as a kinase inhibitor. It is derived from d-xylose and has been shown to have anticancer properties. Afamelanotide acetate inhibits the activity of kinases, which are enzymes that play a crucial role in tumor growth and progression. This drug induces apoptosis, or programmed cell death, in cancer cells and has been shown to be effective against various types of cancer, including Chinese hamster ovary (CHO) cells. Afamelanotide acetate has also been found in human urine and may have potential as a biomarker for cancer diagnosis or monitoring.</p>

<p>Please enquire for more information about Acetyl-(3,4-dehydro-Pro1,4-fluoro-D-Phe2,D-Trp3·6)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Acetyl-(D-Trp1,4-chloro-D-Phe2,D-Trp3,D-Arg6,D-Ala10)-LHRH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Acetyl-Exenatide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Des-acetyl)-a-MSH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>