Doripenem

CAS: 148016-81-3

Ref. 3D-AD15636

Product Information

• Name: Doripenem
• Synonyms: (+)-(4R,5S,6S)-6-[(1R)-1-Hydro-Xyethyl]-4-Methyl-7-Oxo-3-[[(3S,5S)-5-[(Sulfamoylamino)-Methyl]-3-Pyrrolidinyl]Thio]-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid, (4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-, 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-, Doribax, Doripenem Sterile, Finibax, S 4661

Description

Doripenem is a member of the carbapenem group of antibiotics. It inhibits protein synthesis by binding to penicillin-binding proteins, which are enzymes that maintain the integrity of bacterial cell walls. Doripenem has a broad spectrum of activity and is used to treat infections caused by gram-positive bacteria such as methicillin resistant Staphylococcus aureus (MRSA), Streptococcus pneumoniae, and Enterococcus faecium. Doripenem also has inhibitory properties against wild-type strains of Escherichia coli and Klebsiella pneumoniae. The drug is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations occurring in 1 to 2 hours following oral administration. This antibiotic can be used to treat infections in both the community and hospital settings.

• Brand: Biosynth

Chemical properties

• Molecular weight: 420.51 g/mol
• Formula: C₁₅H₂₄N₄O₆S₂
• Purity: Min. 95%
• Color/Form: White Powder