Geneticin sulfate

CAS: 108321-42-2

Ref. 3D-AG11347

Product Information

• Name: Geneticin sulfate
• Synonyms: G418 sulfate, (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol, <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2), <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt), ANTIBIOTIC G-418 Sulfate, G-418 Sulfate, G-418 Sulphate, G418 Disulfate Cell Culture Tested, G418 Disulfate Plant Cell Culture Tested, G418 Solution, G418 Sulfate, Sulfuric Acid, D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2), D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)

Description

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 692.71 g/mol
• Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
• Purity: Min. 98 Area-%
• Color/Form: White Powder