Product Information
- S 18986-1
- 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (S)-
- (3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide
- 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
S 18986 is a novel molecule that binds to the glutamate receptor. It has been shown to protect neurons against glutamate-induced cell death in vitro and in vivo, as well as reversing memory deficits in aged mice. S 18986 also increases the production of neurotrophic factors and enhances neuronal function. The pharmacokinetics of S 18986 have been studied using a population modeling approach. This approach provides an asymmetric synthesis route for the preparation of this compound. S 18986 has also been shown to increase locomotor activity, which may be due to its ability to potentiate GABAergic transmission.END>
Chemical properties
Technical inquiry about: 3D-AHA34020 S 18986
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