Pirazinecarboxamide

CAS: 98-96-4

Ref. 3D-AP27270

Product Information

• Name: Pirazinecarboxamide
• Synonyms: PyrazinamidePyrazinoic acid amideD-50, 2-(Aminocarbonyl)pyrazine, 2-Carbamylpyrazine, 2-Carboxamidopyrazine, 2-​ Pyrazinecarboxamide, Aldinamid, Aldinamide, D 50, Eprazin, Farmizina, Isopas, Mk 56, Novamid, Nsc 14911, Pirazimida, Pirazinamid, Pirazinamida, Pyrafat, Pyramizade, Pyrazide, Pyrazinamid, Pyrazine carboxylamide, Pyrazine-2-Carboxamide, Pyrazinecarboxamide, Pyrazinecarboxylic acid amide, Pyrazinoic acid amide, Rifafour e-200, Rifcin, Rozide, Tebrazid, Unipyranamide, Zinamide, α-Pyrazinamide

Description

Pirazinecarboxamide is a prodrug that is converted to its active form pirazinamidetriethanolamine by nitrate reductase. It has been shown to be effective in the treatment of tuberculosis and has been shown to inhibit the growth of antibiotic-resistant strains of Mycobacterium tuberculosis. Pirazinecarboxamide has also shown efficacy in treating bowel disease and familial hypercholesterolaemia. The mechanism of action for pirazinecarboxamide is not well understood, but it may involve an effect on Toll-like receptor (TLR) signalling pathways or inhibition of nitrate reductase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 123.11 g/mol
• Formula: C₅H₅N₃O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
• InChI key: InChIKey=IPEHBUMCGVEMRF-UHFFFAOYSA-N
• SMILES: NC(=O)c1cnccn1