Roxithromycin

CAS: 80214-83-1

Ref. 3D-AR27766

Product Information

• Name: Roxithromycin
• Synonyms: (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime] erythromycinAssoralBrilid, (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2-methoxyethoxy)methoxy]imino}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one (non-preferred name), 5-(3,4,6-Trideoxy-3-Dimethylamino-Beta-D-Xylo-Hexopyranosyloxy)-3-(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-Alpha-L-Ribo-Hexopyranosyloxy)-6,11,12-Trihydroxy-9-(2-Methoxyethoxy)Methoxyimino-2,4,6,8,10,12-Hexamethylpentadecan-13-Olide, Assoral, Biaxsig, Brilid, Claramid, Erythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime], (9E)-, Forilin, Overal, Oxacyclotetradecane, erythromycin deriv., Rossitrol, Rotramin, Roxacin, Roxar, Roxeptin, Roxibest-A, Roxid, Roxid-M, Roximycin, Roxithromycin A, Roxithromycine, Roxl 150, Roxxibid, Roxythromycin, Ru 28965, Ru 965, Rulid, Rulide, Surlid, Xthrocin

Description

Roxithromycin is a macrolide antibiotic that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. It has been shown to be effective against chronic respiratory tract infections caused by gram-positive species, such as chronic cough and chronic bronchitis. Roxithromycin also has anti-inflammatory properties that may be due to its inhibition of prostaglandin synthesis. Roxithromycin is a prodrug that is converted in vivo into roxithromycin, its active form. The dextran sulfate-aided analytical method for roxithromycin has been found to be more accurate than other methods used for detecting this drug in human polymorphonuclear leukocytes and saliva samples.

• Brand: Biosynth

Chemical properties

• Molecular weight: 837.05 g/mol
• Formula: C₄₁H₇₆N₂O₁₅
• Purity: Min. 95%
• Color/Form: White Powder