Product Information
Name:A 1070722
Synonyms:
- 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea
Brand:Biosynth
Description:High affinity inhibitor of glycogen synthase kinase GSK-3 with Ki of 0.6 nM. A 1070722 showed favourable characteristics for the penetration across blood brain barrier. A 1070722 was also shown to reduce the phosphorylation of microtubule-associated protein Tau.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:362.31 g/mol
Formula:C17H13F3N4O2
Purity:Min. 95%
Color/Form:Solid
InChI:InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)
InChI key:InChIKey=VQPBIJGXSXEOCU-UHFFFAOYSA-N
SMILES:COc1ccc2c(NC(=O)Nc3cccc(C(F)(F)F)n3)ccnc2c1
Technical inquiry about: A 1070722
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