Estimated delivery in United States, on Tuesday 21 May 2024
Product Information
Name:
A 1070722
Synonyms:
- 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea
CAS:
Description:
High affinity inhibitor of glycogen synthase kinase GSK-3 with Ki of 0.6 nM. A 1070722 showed favourable characteristics for the penetration across blood brain barrier. A 1070722 was also shown to reduce the phosphorylation of microtubule-associated protein Tau.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
362.31 g/mol
Formula:
C17H13F3N4O2
Purity:
Min. 95%
Color/Form:
Solid
InChI:
InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)
InChI key:
InChIKey=VQPBIJGXSXEOCU-UHFFFAOYSA-N
SMILES:
COc1ccc2c(NC(=O)Nc3cccc(C(F)(F)F)n3)ccnc2c1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 3D-BA166127 A 1070722
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