BLU 554

CAS: 1707289-21-1

Ref. 3D-BB160379

Product Information

• Name: BLU 554
• Synonyms: N-((3S,4S)-3-((6-(2,6-Dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)tetrahydro-2H-pyran-4-yl)acrylamide
• Brand: Biosynth
• Description: A potent and selective covalent inhibitor of fibroblast growth factor receptor 4 (FGFR4). This receptor tyrosine kinase activates an oncogenic driver in hepatocellular carcinoma, the fibroblast growth factor 19 (FGF19). The FGFR4 inhibitor is therefore a promising candidate for the treatment of advanced liver cancer.

Chemical properties

• Molecular weight: 503.38 g/mol
• Formula: C₂₄H₂₄Cl₂N₄O₄
• Purity: Min. 95%
• Color/Form: White Powder