Bortezomib - Bio-X ™

CAS: 179324-69-7

Ref. 3D-BB164258

Product Information

• Name: Bortezomib - Bio-X ™
• Synonyms: [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acidRadiciol
• Brand: Biosynth
• Description: Bortezomib is a selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of protein breakdown affects several metabolic pathways and leads to cell death. The compound is effective in treating t-cell lymphomas and multiple myeloma because it prevents the binding of myeloma cells to bone marrow stroma and inhibits osteoclast differentiation.

Chemical properties

• Molecular weight: 384.24 g/mol
• Formula: C₁₉H₂₅BN₄O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
• InChI key: InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N
• SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O