Product Information
Name:BRD 3308
Synonyms:
- 4-4-Acetamido-N-(2-amino-4-fluorophenyl)benzamideBRD3308
Brand:Biosynth
Description:Inhibitor of histone deacetylase 3 (HDAC3) with IC50 in nanomolar range. BRD 9908 was shown to preserve the insulin-secreting pancreatic cells in nonobese diabetic mice. BRD 3308 supressed infiltration of mononuclear cells and prevented β-cell death in vivo as well as increased basal insulin secretion in vitro. Studies on HIV infection models showed that HDAC3 inhibition by BRD 3308 disrupts the HIV latency by increasing the gene expression from HIV promoter.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:287.29 g/mol
Formula:C15H14FN3O2
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C15H14FN3O2/c1-9(20)18-12-5-2-10(3-6-12)15(21)19-14-7-4-11(16)8-13(14)17/h2-8H,17H2,1H3,(H,18,20)(H,19,21)
InChI key:InChIKey=RRJDFENBXIEAPD-UHFFFAOYSA-N
SMILES:CC(=O)Nc1ccc(C(=O)Nc2ccc(F)cc2N)cc1
Technical inquiry about: BRD 3308
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