Product Information
Name:BT 18
Synonyms:
- ([4-[5- [(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]-2- methoxyphenyl]piperazin-1-yl]-[4-fluoro-2-(trifluoromethyl)- ph enyl]methanone)BT18
Brand:Biosynth
Description:Activator of RET signalling cascade and a derivative of a GFL mimetic compound BT 13. Molecular docking calculations and molecular dynamics simulations were performed in GDNF−GFRα1−RetA complex and showed that BT 18 binds to the allosteric site in GFRα1 as well as RetA surface interfacing GFRα1.
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Chemical properties
Molecular weight:637.64 g/mol
Formula:C30H31F4N3O6S
Purity:Min. 95%
Color/Form:Solid
Technical inquiry about: BT 18
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