BT 18

CAS: 924811-53-0

Ref. 3D-BB170419

Product Information

• Name: BT 18
• Synonyms: ([4-[5- [(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]-2- methoxyphenyl]piperazin-1-yl]-[4-fluoro-2-(trifluoromethyl)- ph enyl]methanone)BT18
• Brand: Biosynth
• Description: Activator of RET signalling cascade and a derivative of a GFL mimetic compound BT 13. Molecular docking calculations and molecular dynamics simulations were performed in GDNF−GFRα1−RetA complex and showed that BT 18 binds to the allosteric site in GFRα1 as well as RetA surface interfacing GFRα1.

Chemical properties

• Molecular weight: 637.64 g/mol
• Formula: C₃₀H₃₁F₄N₃O₆S
• Purity: Min. 95%
• Color/Form: Solid