Carmustine - Bio-X ™

CAS: 154-93-8

Ref. 3D-BC164289

Product Information

• Name: Carmustine - Bio-X ™
• Synonyms: N,N'-bis(2-chloroethyl)-N-nitrosoureaNSC-409962, 1,3-Bis(2-Chloroethyl)-1-Nitroso-Urea, 1,3-Bis(2-chlorethyl)-1-nitrosourea, 1,3-Bis(2-chloroethyl)-1-nitrosourea, 1,3-Bis(2-chloroethyl)nitrosourea, 1,3-Bis(β-chloroethyl)-1-nitrosourea, Bcnu, Becenum, Becenun, BiCNU, Carmubris, Carmustin, Carmustina, Dti 015, Fda 0345, Gliadel, Gliadel Wafer, N,N'-Bis(2-chloroethyl)-N-nitrosourea, Nitrumon, Nsc 409962, Sk 27702, Sri 1720, Urea, 1,3-bis(2-chloroethyl)-1-nitroso-, Urea, N,N'-bis(2-chloroethyl)-N'-nitroso-

Description

Carmustine is a DNA alkylating agent which also cross-links DNA. As a result, Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, means it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.

Carmustine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Brand: Biosynth

Chemical properties

• Molecular weight: 214.05 g/mol
• Formula: C₅H₉Cl₂N₃O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
• InChI key: InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N
• SMILES: O=NN(CCCl)C(=O)NCCCl