Product Information
Name:Cyclosporin G
Brand:Biosynth
Description:Cyclosporin G is an immunosuppressive agent, which is derived from fungal sources with a specific mode of action that involves inhibiting calcineurin. The source of Cyclosporin G is primarily from the fermentation of the fungus *Tolypocladium inflatum*. Its mode of action involves binding to the cytosolic protein cyclophilin in T-lymphocytes, which subsequently inhibits the phosphatase activity of calcineurin. This inhibition prevents the dephosphorylation and nuclear translocation of the nuclear factor of activated T-cells (NFAT), thereby reducing the transcription of interleukin-2 and other cytokines critical for T-cell activation.
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Chemical properties
Molecular weight:1,216.64 g/mol
Formula:C63H113N11O12
Purity:Min. 95%
Technical inquiry about: Cyclosporin G
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