Product Information
Name:DMH 1
Synonyms:
- 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinolineDMH-1
Brand:Biosynth
Description:
A specific inhibitor of Bone Morphogenetic Protein (BMP) type 1 receptors ALK2 and ALK3 (IC50 < 0.5 µM). Dorsomorphin analog that exclusively targets the BMP but not VEGF signaling. It is able to inhibit the BMP-induced Smad1/5/8 activation but not the p38/MAP kinase signaling or Activin A-induced Smad2 activation.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:380.44 g/mol
Formula:C24H20N4O
Purity:Min. 95%
Color/Form:Solid
InChI:InChI=1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChI key:InChIKey=JMIFGARJSWXZSH-UHFFFAOYSA-N
SMILES:CC(C)Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1
Technical inquiry about: DMH 1
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