DO 264

CAS: 2301866-59-9

Ref. 3D-BD167529

Product Information

• Name: DO 264
• Synonyms: DO264
• Brand: Biosynth
• Description: Inhibits lysophosphatidylserine hydrolysis by the integral membrane serine hydrolase ABHD12 (IC50 = 1.3 µM). Raised levels of lysophosphatidylserine were observed in mouse brain in vivo and in primary human macrophages. DO 264 had proinflammatory effects, following infection with lymphocytic choriomeningitis virus (LCV) clone 13 in mice, resulting in severe inflammatory lung damage.

Chemical properties

• Molecular weight: 558.4 g/mol
• Formula: C₂₃H₂₀Cl₂F₃N₅O₂S
• Purity: Min. 95%
• Color/Form: White/Off-White Solid