Product Information
Name:DO 264
Synonyms:
- DO264
Brand:Biosynth
Description:Inhibits lysophosphatidylserine hydrolysis by the integral membrane serine hydrolase ABHD12 (IC50 = 1.3 µM). Raised levels of lysophosphatidylserine were observed in mouse brain in vivo and in primary human macrophages. DO 264 had proinflammatory effects, following infection with lymphocytic choriomeningitis virus (LCV) clone 13 in mice, resulting in severe inflammatory lung damage.
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Chemical properties
Molecular weight:558.4 g/mol
Formula:C23H20Cl2F3N5O2S
Purity:Min. 95%
Color/Form:White/Off-White Solid
Technical inquiry about: DO 264
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