Product Information
Name:ES9-17
Synonyms:
- 5-Bromo-N-phenyl-2-thiophenesulfonamide
Brand:Biosynth
Description:Inhibitor of clathrin-mediated endocytosis (CME) and ligand to the clathrin heavy chain (CHC). ES9-17 is an inhibitor of the CHC function with EC50 of 13 μM in plant model Arabidopsis thaliana. ES9-17 is a non-protonophoric CME inhibitor and it does not alter the cytoplasmic pH levels substantially. In a mammalian cell line HeLa, ES9-17 reduced the uptake of transferrin, which is a CME-driven process.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:318.21 g/mol
Formula:C10H8BrNO2S2
Purity:Min. 95%
Color/Form:Off-White Powder
InChI:InChI=1S/C10H8BrNO2S2/c11-9-6-7-10(15-9)16(13,14)12-8-4-2-1-3-5-8/h1-7,12H
InChI key:InChIKey=AIZXCKZVUXCHAP-UHFFFAOYSA-N
SMILES:O=S(=O)(Nc1ccccc1)c1ccc(Br)s1
Technical inquiry about: ES9-17
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